locus-tag	class	description
AR505_0004	COG0183	Belongs to the thiolase family
AR505_0006	COG0552	protein localization to endoplasmic reticulum
AR505_0011	COG0084	hydrolase, TatD family'
AR505_0014	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AR505_0025	COG1201	RNA secondary structure unwinding
AR505_0030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_0031	COG1120	ATPase activity
AR505_0033	COG0187	DNA topoisomerase II activity
AR505_0034	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AR505_0037	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AR505_0038	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AR505_0039	COG1201	RNA secondary structure unwinding
AR505_0040	COG2181	nitrate reductase activity
AR505_0040	COG0247	lactate metabolic process
AR505_0047	COG3118	belongs to the thioredoxin family
AR505_0048	COG0492	ferredoxin-NADP+ reductase activity
AR505_0051	COG1242	4 iron, 4 sulfur cluster binding
AR505_0052	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AR505_0054	COG0085	RNA polymerase activity
AR505_0055	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AR505_0056	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AR505_0060	COG0284	orotidine-5'-phosphate decarboxylase activity
AR505_0065	COG0101	tRNA pseudouridine synthase activity
AR505_0066	COG0151	Belongs to the GarS family
AR505_0067	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AR505_0068	COG0252	asparaginase activity
AR505_0070	COG2813	Specifically methylates the guanine in position
AR505_0071	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AR505_0076	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AR505_0081	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AR505_0082	COG2017	converts alpha-aldose to the beta-anomer
AR505_0092	COG0459	protein refolding
AR505_0095	COG0484	heat shock protein binding
AR505_0100	COG0352	thiamine-phosphate diphosphorylase activity
AR505_0102	COG2022	thiamine diphosphate biosynthetic process
AR505_0106	COG3415	Transposase
AR505_0106	COG2801	Transposase and inactivated derivatives
AR505_0107	COG3415	Transposase
AR505_0107	COG2801	Transposase and inactivated derivatives
AR505_0109	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AR505_0110	COG5012	cobalamin binding
AR505_0111	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AR505_0115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AR505_0118	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AR505_0123	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AR505_0125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AR505_0127	COG0730	response to heat
AR505_0130	COG0417	DNA replication proofreading
AR505_0131	COG0012	GTP binding
AR505_0132	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AR505_0143	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AR505_0144	COG0006	proline dipeptidase activity
AR505_0145	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AR505_0152	COG0028	Belongs to the TPP enzyme family
AR505_0153	COG0028	Belongs to the TPP enzyme family
AR505_0154	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AR505_0157	COG0436	Aminotransferase
AR505_0158	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AR505_0159	COG0019	diaminopimelate decarboxylase activity
AR505_0160	COG0527	aspartate kinase activity
AR505_0161	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AR505_0162	COG1522	sequence-specific DNA binding
AR505_0163	COG3264	Mechanosensitive ion channel
AR505_0163	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AR505_0167	COG3875	lactate racemase activity
AR505_0168	COG0247	lactate metabolic process
AR505_0168	COG2181	nitrate reductase activity
AR505_0169	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AR505_0177	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AR505_0180	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AR505_0187	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AR505_0191	COG1304	FMN binding
AR505_0193	COG0477	Major facilitator Superfamily
AR505_0194	COG0298	carbon dioxide binding
AR505_0196	COG3402	PFAM membrane-flanked domain
AR505_0198	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AR505_0199	COG1522	sequence-specific DNA binding
AR505_0200	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AR505_0201	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AR505_0202	COG0154	amidase activity
AR505_0203	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AR505_0205	COG0004	ammonium transporteR
AR505_0206	COG0347	Belongs to the P(II) protein family
AR505_0209	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AR505_0215	COG0675	Transposase, IS605 OrfB family
AR505_0218	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AR505_0219	COG0088	Forms part of the polypeptide exit tunnel
AR505_0220	COG0089	rRNA binding
AR505_0221	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AR505_0222	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AR505_0223	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AR505_0224	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AR505_0225	COG0255	Belongs to the universal ribosomal protein uL29 family
AR505_0228	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AR505_0229	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AR505_0233	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AR505_0234	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AR505_0238	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AR505_0240	COG0200	Binds to the 23S rRNA
AR505_0248	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AR505_0251	COG0528	UMP kinase activity
AR505_0261	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AR505_0262	COG0563	adenylate kinase activity
AR505_0263	COG0277	FAD linked oxidase domain protein
AR505_0270	COG0612	Peptidase, M16
AR505_0274	COG2048	Heterodisulfide reductase, subunit B
AR505_0278	COG0003	Pfam Anion-transporting ATPase
AR505_0281	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AR505_0284	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AR505_0285	COG0733	neurotransmitter:sodium symporter activity
AR505_0287	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AR505_0290	COG0675	Transposase, IS605 OrfB family
AR505_0291	COG2848	UPF0210 protein
AR505_0293	COG0460	homoserine dehydrogenase
AR505_0295	COG0589	response to stress
AR505_0304	COG1120	ATPase activity
AR505_0305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_0307	COG2226	methyltransferase
AR505_0308	COG1120	ATPase activity
AR505_0309	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_0312	COG2226	methyltransferase
AR505_0359	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AR505_0364	COG0589	response to stress
AR505_0371	COG0675	Transposase, IS605 OrfB family
AR505_0377	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AR505_0381	COG1797	cobyrinic acid a,c-diamide synthase activity
AR505_0385	COG0475	glutathione-regulated potassium exporter activity
AR505_0387	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AR505_0391	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AR505_0393	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AR505_0394	COG0124	histidyl-tRNA synthetase
AR505_0397	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AR505_0405	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AR505_0408	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_0409	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_0410	COG1120	ATPase activity
AR505_0412	COG1131	(ABC) transporter
AR505_0417	COG1131	(ABC) transporter
AR505_0421	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AR505_0425	COG0516	GMP reductase activity
AR505_0425	COG0517	IMP dehydrogenase activity
AR505_0427	COG0574	Belongs to the PEP-utilizing enzyme family
AR505_0427	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AR505_0429	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AR505_0430	COG1144	Oxidoreductase
AR505_0431	COG0674	pyruvate-flavodoxin oxidoreductase activity
AR505_0432	COG1013	pyruvate-flavodoxin oxidoreductase activity
AR505_0436	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AR505_0437	COG0540	Belongs to the ATCase OTCase family
AR505_0445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AR505_0448	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AR505_0449	COG2195	Cleaves the N-terminal amino acid of tripeptides
AR505_0451	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AR505_0456	COG0697	spore germination
AR505_0457	COG0583	DNA-binding transcription factor activity
AR505_0458	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AR505_0461	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AR505_0464	COG1234	tRNA 3'-trailer cleavage
AR505_0466	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
AR505_0470	COG0148	phosphopyruvate hydratase activity
AR505_0473	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AR505_0477	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_0478	COG1120	ATPase activity
AR505_0481	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AR505_0483	COG1454	alcohol dehydrogenase
AR505_0486	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AR505_0486	COG0140	phosphoribosyl-ATP diphosphatase activity
AR505_0487	COG0107	imidazoleglycerol-phosphate synthase activity
AR505_0488	COG0131	Imidazoleglycerol-phosphate dehydratase
AR505_0490	COG1605	Chorismate mutase
AR505_0490	COG0077	Prephenate dehydratase
AR505_0493	COG3550	peptidyl-serine autophosphorylation
AR505_0494	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AR505_0496	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AR505_0497	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AR505_0498	COG0675	Transposase, IS605 OrfB family
AR505_0500	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AR505_0501	COG0505	Belongs to the CarA family
AR505_0503	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AR505_0504	COG0505	Belongs to the CarA family
AR505_0508	COG1830	Aldolase
AR505_0509	COG1465	3-dehydroquinate synthase
AR505_0510	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AR505_0511	COG0083	homoserine kinase activity
AR505_0512	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AR505_0516	COG0675	Transposase, IS605 OrfB family
AR505_0517	COG0488	(ABC) transporter
AR505_0520	COG1120	ATPase activity
AR505_0521	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_0522	COG1373	ATPase (AAA superfamily
AR505_0523	COG0675	Transposase, IS605 OrfB family
AR505_0526	COG1033	growth of symbiont in host cell
AR505_0526	COG2409	Drug exporters of the RND superfamily
AR505_0527	COG3177	Filamentation induced by cAMP protein fic
AR505_0531	COG0473	3-isopropylmalate dehydrogenase activity
AR505_0540	COG0463	Glycosyl transferase, family 2
AR505_0541	COG1088	dTDP-glucose 4,6-dehydratase activity
AR505_0542	COG0028	Belongs to the TPP enzyme family
AR505_0546	COG0402	S-adenosylhomocysteine deaminase activity
AR505_0547	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AR505_0549	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AR505_0550	COG1216	Glycosyl transferase, family 2
AR505_0553	COG1088	dTDP-glucose 4,6-dehydratase activity
AR505_0554	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AR505_0557	COG3955	Domain of unknown function (DUF1919)
AR505_0558	COG3475	LICD family
AR505_0559	COG1442	glycosyl transferase family 8
AR505_0561	COG1216	Glycosyl transferase, family 2
AR505_0561	COG1442	glycosyl transferase family 8
AR505_0578	COG0571	ribonuclease III activity
AR505_0579	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AR505_0580	COG0675	Transposase, IS605 OrfB family
AR505_0583	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AR505_0584	COG4279	zinc finger
AR505_0592	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AR505_0596	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AR505_0601	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AR505_0609	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AR505_0610	COG0083	homoserine kinase activity
AR505_0613	COG4581	dead DEAH box helicase
AR505_0615	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AR505_0616	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AR505_0617	COG1546	Belongs to the CinA family
AR505_0617	COG1058	Belongs to the CinA family
AR505_0620	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AR505_0622	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AR505_0624	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AR505_0626	COG0371	Dehydrogenase
AR505_0627	COG0655	NAD(P)H dehydrogenase (quinone) activity
AR505_0630	COG2033	superoxide reductase activity
AR505_0631	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AR505_0632	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AR505_0633	COG0066	3-isopropylmalate dehydratase activity
AR505_0634	COG0473	3-isopropylmalate dehydrogenase activity
AR505_0639	COG0675	Transposase, IS605 OrfB family
AR505_0643	COG0352	thiamine-phosphate diphosphorylase activity
AR505_0644	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AR505_0645	COG1966	Carbon starvation protein
AR505_0650	COG0351	phosphomethylpyrimidine kinase
AR505_0662	COG1401	restriction endodeoxyribonuclease activity
AR505_0669	COG3415	Transposase
AR505_0669	COG2801	Transposase and inactivated derivatives
AR505_0672	COG0137	argininosuccinate synthase activity
AR505_0673	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AR505_0674	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AR505_0675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AR505_0676	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AR505_0677	COG0675	Transposase, IS605 OrfB family
AR505_0678	COG0372	Belongs to the citrate synthase family
AR505_0680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AR505_0688	COG1335	isochorismatase
AR505_0693	COG0251	oxidation-reduction process
AR505_0694	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AR505_0695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AR505_0696	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AR505_0700	COG1773	rubredoxin
AR505_0701	COG1129	ABC transporter
AR505_0705	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AR505_0706	COG0519	Catalyzes the synthesis of GMP from XMP
AR505_0708	COG3415	Transposase
AR505_0708	COG2801	Transposase and inactivated derivatives
AR505_0709	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AR505_0709	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AR505_0710	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AR505_0710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AR505_0712	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AR505_0713	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_0714	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_0734	COG1733	regulation of RNA biosynthetic process
AR505_0737	COG0385	Bile acid
AR505_0741	COG1739	Uncharacterized protein family UPF0029
AR505_0742	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AR505_0746	COG0668	transmembrane transport
AR505_0748	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AR505_0753	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AR505_0756	COG1132	(ABC) transporter
AR505_0758	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AR505_0762	COG0277	FAD linked oxidase domain protein
AR505_0763	COG2086	electron transfer activity
AR505_0764	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AR505_0766	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AR505_0767	COG0072	phenylalanine-tRNA ligase activity
AR505_0770	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AR505_0770	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AR505_0771	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AR505_0786	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AR505_0791	COG3275	phosphorelay sensor kinase activity
AR505_0801	COG1959	2 iron, 2 sulfur cluster binding
AR505_0805	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AR505_0806	COG0477	Major facilitator Superfamily
AR505_0812	COG1283	sodium-dependent phosphate transmembrane transporter activity
AR505_0814	COG1199	ATP-dependent helicase activity
AR505_0828	COG2255	four-way junction helicase activity
AR505_0831	COG1846	Transcriptional regulator
AR505_0832	COG1119	ATPase activity
AR505_0835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AR505_0835	COG4651	solute:proton antiporter activity
AR505_0836	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AR505_0838	COG1122	ATPase activity
AR505_0841	COG0310	cobalt ion transport
AR505_0854	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AR505_0886	COG1061	Type III restriction enzyme res subunit
AR505_0891	COG1196	nuclear chromosome segregation
AR505_0893	COG1373	ATPase (AAA superfamily
AR505_0902	COG1032	radical SAM domain protein
AR505_0903	COG0675	Transposase, IS605 OrfB family
AR505_0907	COG0312	modulator of DNA gyrase
AR505_0908	COG0312	modulator of DNA gyrase
AR505_0911	COG2814	Major facilitator Superfamily
AR505_0928	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AR505_0930	COG3422	double-strand break repair
AR505_0932	COG1830	Aldolase
AR505_0935	COG0613	PHP domain protein
AR505_0939	COG0719	Fe-S assembly protein
AR505_0942	COG0588	phosphoglycerate mutase activity
AR505_0944	COG1115	amino acid carrier protein
AR505_0947	COG0523	cobalamin synthesis protein
AR505_0950	COG5012	cobalamin binding
AR505_0955	COG1733	regulation of RNA biosynthetic process
AR505_0956	COG1151	hydroxylamine reductase activity
AR505_0958	COG5377	YqaJ viral recombinase family
AR505_0963	COG1418	mRNA catabolic process
AR505_0967	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AR505_0968	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AR505_0969	COG0163	prenyltransferase activity
AR505_0972	COG0495	leucyl-tRNA aminoacylation
AR505_0973	COG3615	Tellurite resistance protein tehB
AR505_0973	COG0500	methyltransferase
AR505_0975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AR505_0981	COG2226	methyltransferase
AR505_0982	COG0640	Transcriptional regulator
AR505_0984	COG1489	DNA binding
AR505_0994	COG1489	DNA binding
AR505_0995	COG2252	PERMEase
AR505_1000	COG0300	oxidoreductase activity
AR505_1008	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AR505_1012	COG3655	Transcriptional regulator
AR505_1017	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AR505_1027	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AR505_1029	COG0167	dihydroorotate dehydrogenase activity
AR505_1030	COG0543	2 iron, 2 sulfur cluster binding
AR505_1037	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AR505_1041	COG1648	precorrin-2 dehydrogenase activity
AR505_1041	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AR505_1044	COG0113	porphobilinogen synthase activity
AR505_1047	COG0069	glutamate synthase activity
AR505_1047	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AR505_1059	COG0822	iron-sulfur transferase activity
AR505_1063	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AR505_1064	COG5012	cobalamin binding
AR505_1067	COG5012	cobalamin binding
AR505_1072	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AR505_1073	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AR505_1076	COG2814	Major facilitator Superfamily
AR505_1084	COG1722	exodeoxyribonuclease VII activity
AR505_1085	COG1570	exodeoxyribonuclease VII activity
AR505_1092	COG1857	crispr-associated protein
AR505_1095	COG1518	maintenance of DNA repeat elements
AR505_1100	COG0530	calcium, potassium:sodium antiporter activity
AR505_1101	COG0488	(ABC) transporter
AR505_1104	COG0574	Belongs to the PEP-utilizing enzyme family
AR505_1104	COG3848	Pyruvate phosphate dikinase
AR505_1115	COG1201	RNA secondary structure unwinding
AR505_1118	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AR505_1121	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AR505_1132	COG1074	ATP-dependent DNA helicase activity
AR505_1136	COG1492	cobalamin metabolic process
AR505_1139	COG0420	3'-5' exonuclease activity
AR505_1140	COG4717	serine-type aminopeptidase activity
AR505_1142	COG0358	DNA primase activity
AR505_1143	COG0606	chelatase, subunit chli
AR505_1149	COG1980	fructose-bisphosphate aldolase activity
AR505_1150	COG0017	Asparaginyl-tRNA synthetase
AR505_1155	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AR505_1159	COG0512	Glutamine amidotransferase of anthranilate synthase
AR505_1164	COG0159	tryptophan synthase activity
AR505_1165	COG1618	nucleotide phosphatase activity, acting on free nucleotides
AR505_1166	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
AR505_1168	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AR505_1169	COG3275	phosphorelay sensor kinase activity
AR505_1170	COG0745	RESPONSE REGULATOR receiver
AR505_1170	COG2972	Histidine kinase
AR505_1176	COG1309	transcriptional regulator
AR505_1177	COG2409	Drug exporters of the RND superfamily
AR505_1180	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AR505_1180	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AR505_1181	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AR505_1181	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AR505_1183	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AR505_1191	COG0215	cysteine-tRNA ligase activity
AR505_1192	COG1045	serine acetyltransferase
AR505_1194	COG2226	methyltransferase
AR505_1197	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_1198	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AR505_1199	COG0436	Aminotransferase
AR505_1204	COG0037	tRNA processing
AR505_1209	COG2255	four-way junction helicase activity
AR505_1211	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AR505_1219	COG0675	Transposase, IS605 OrfB family
AR505_1222	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AR505_1222	COG1918	ferrous iron import across plasma membrane
AR505_1223	COG1918	ferrous iron import across plasma membrane
AR505_1226	COG0640	Transcriptional regulator
AR505_1227	COG2217	Heavy metal translocating P-type atpase
AR505_1228	COG0443	Heat shock 70 kDa protein
AR505_1233	COG1187	pseudouridine synthase activity
AR505_1235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AR505_1237	COG1733	regulation of RNA biosynthetic process
AR505_1238	COG1971	Probably functions as a manganese efflux pump
AR505_1267	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AR505_1274	COG0585	pseudouridine synthase activity
AR505_1277	COG1793	dna ligase
AR505_1278	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AR505_1282	COG0045	succinate-CoA ligase (ADP-forming) activity
AR505_1282	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AR505_1282	COG1042	CoA-binding domain protein
AR505_1288	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AR505_1291	COG1120	ATPase activity
AR505_1292	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_1295	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AR505_1297	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AR505_1299	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AR505_1299	COG0551	DNA topoisomerase type I activity
AR505_1302	COG0864	Transcriptional regulator
AR505_1303	COG0367	asparagine synthase
AR505_1304	COG0285	dihydrofolate synthase activity
AR505_1305	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AR505_1310	COG2076	Multidrug Resistance protein
AR505_1311	COG2076	Multidrug Resistance protein
AR505_1314	COG3655	Transcriptional regulator
AR505_1317	COG2226	methyltransferase
AR505_1318	COG1362	aminopeptidase activity
AR505_1321	COG0513	Belongs to the DEAD box helicase family
AR505_1323	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AR505_1324	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AR505_1325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AR505_1329	COG5012	cobalamin binding
AR505_1330	COG5012	cobalamin binding
AR505_1333	COG5012	cobalamin binding
AR505_1335	COG4868	Belongs to the UPF0371 family
AR505_1336	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AR505_1337	COG0513	Belongs to the DEAD box helicase family
AR505_1341	COG0423	glycine-tRNA ligase activity
AR505_1342	COG0517	IMP dehydrogenase activity
AR505_1343	COG0589	response to stress
AR505_1346	COG0492	ferredoxin-NADP+ reductase activity
AR505_1353	COG1592	Rubrerythrin
AR505_1357	COG1253	flavin adenine dinucleotide binding
AR505_1374	COG1185	polyribonucleotide nucleotidyltransferase activity
AR505_1376	COG0473	3-isopropylmalate dehydrogenase activity
AR505_1377	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AR505_1382	COG0145	ligase activity
AR505_1392	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AR505_1401	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AR505_1407	COG1078	dGTPase activity
AR505_1412	COG0489	protein tyrosine kinase activity
AR505_1414	COG0602	queuosine metabolic process
AR505_1416	COG0720	synthase
AR505_1423	COG2801	Transposase and inactivated derivatives
AR505_1423	COG3415	Transposase
AR505_1426	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AR505_1431	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AR505_1437	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AR505_1440	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AR505_1441	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AR505_1448	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AR505_1449	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AR505_1453	COG0051	transcription antitermination factor activity, RNA binding
AR505_1454	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AR505_1455	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AR505_1456	COG0049	tRNA binding
AR505_1460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AR505_1464	COG0076	glutamate decarboxylase activity
AR505_1465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AR505_1474	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AR505_1474	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AR505_1476	COG3259	Nickel-dependent hydrogenase
AR505_1477	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
AR505_1485	COG1185	polyribonucleotide nucleotidyltransferase activity
AR505_1491	COG1131	(ABC) transporter
AR505_1494	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AR505_1495	COG3177	Filamentation induced by cAMP protein fic
AR505_1496	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AR505_1500	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AR505_1506	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_1507	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_1511	COG2217	Heavy metal translocating P-type atpase
AR505_1513	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AR505_1516	COG1185	polyribonucleotide nucleotidyltransferase activity
AR505_1525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_1526	COG1120	ATPase activity
AR505_1550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_1551	COG1120	ATPase activity
AR505_1581	COG0402	S-adenosylhomocysteine deaminase activity
AR505_1586	COG0116	Belongs to the methyltransferase superfamily
AR505_1586	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AR505_1588	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AR505_1594	COG0482	sulfurtransferase activity
AR505_1595	COG1691	(AIR) carboxylase
AR505_1599	COG1012	belongs to the aldehyde dehydrogenase family
AR505_1601	COG0430	RNA-3'-phosphate cyclase activity
AR505_1602	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AR505_1602	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AR505_1603	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AR505_1604	COG0235	Class ii aldolase
AR505_1608	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AR505_1611	COG1196	nuclear chromosome segregation
AR505_1613	COG0647	UMP catabolic process
AR505_1615	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AR505_1619	COG0142	geranyltranstransferase activity
AR505_1622	COG1007	ATP synthesis coupled electron transport
AR505_1624	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AR505_1627	COG0839	Belongs to the complex I subunit 6 family
AR505_1629	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AR505_1630	COG0649	NAD binding
AR505_1631	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AR505_1632	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AR505_1633	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AR505_1634	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AR505_1636	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AR505_1638	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AR505_1639	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AR505_1640	COG3415	Transposase
AR505_1640	COG2801	Transposase and inactivated derivatives
AR505_1641	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AR505_1642	COG1850	ribulose-bisphosphate carboxylase activity
AR505_1643	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AR505_1645	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AR505_1647	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AR505_1648	COG3958	Transketolase
AR505_1649	COG3959	Transketolase, thiamine diphosphate binding domain
AR505_1654	COG0157	Belongs to the NadC ModD family
AR505_1656	COG0138	bifunctional purine biosynthesis protein purh
AR505_1657	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AR505_1660	COG0301	tRNA thio-modification
AR505_1662	COG1199	ATP-dependent helicase activity
AR505_1664	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AR505_1670	COG1355	regulation of microtubule-based process
AR505_1671	COG0052	Belongs to the universal ribosomal protein uS2 family
AR505_1680	COG0047	phosphoribosylformylglycinamidine synthase activity
AR505_1681	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AR505_1684	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AR505_1686	COG0659	secondary active sulfate transmembrane transporter activity
AR505_1690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AR505_1692	COG0675	Transposase, IS605 OrfB family
AR505_1695	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AR505_1705	COG1120	ATPase activity
AR505_1706	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_1738	COG0464	growth
AR505_1743	COG0737	Belongs to the 5'-nucleotidase family
AR505_1745	COG0287	Prephenate dehydrogenase
AR505_1755	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AR505_1756	COG0105	UTP biosynthetic process
AR505_1764	COG2246	polysaccharide biosynthetic process
AR505_1767	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AR505_1770	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AR505_1780	COG0281	malic enzyme
AR505_1788	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AR505_1791	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AR505_1796	COG0081	regulation of translation
AR505_1802	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AR505_1802	COG0519	Catalyzes the synthesis of GMP from XMP
AR505_1810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AR505_1818	COG1394	ATPase activity, coupled to movement of substances
AR505_1825	COG1269	ATP hydrolysis coupled proton transport