locus-tag	class	description
A359_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A359_00020	COG0592	DNA-directed DNA polymerase activity
A359_00030	COG0187	DNA topoisomerase II activity
A359_00040	COG1561	YicC-like family, N-terminal region
A359_00060	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A359_00060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A359_00090	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A359_00160	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A359_00170	COG1792	Involved in formation and maintenance of cell shape
A359_00180	COG1077	Cell shape determining protein MreB Mrl
A359_00220	COG0450	alkyl hydroperoxide reductase
A359_00240	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A359_00250	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A359_00260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A359_00280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A359_00280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A359_00300	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A359_00310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A359_00320	COG1862	Preprotein translocase
A359_00330	COG0343	queuine tRNA-ribosyltransferase activity
A359_00350	COG1988	membrane-bound metal-dependent
A359_00360	COG3066	DNA modification
A359_00380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A359_00400	COG1187	pseudouridine synthase activity
A359_00410	COG1028	Short-chain dehydrogenase reductase Sdr
A359_00430	COG0569	domain protein
A359_00440	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A359_00450	COG0795	lipopolysaccharide-transporting ATPase activity
A359_00460	COG0795	lipopolysaccharide-transporting ATPase activity
A359_00480	COG0583	DNA-binding transcription factor activity
A359_00540	COG0511	ligase activity, forming carbon-carbon bonds
A359_00550	COG0439	Biotin carboxylase
A359_00560	COG3023	N-Acetylmuramoyl-L-alanine amidase
A359_00570	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
A359_00590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A359_00600	COG0165	Argininosuccinate lyase
A359_00610	COG1278	Cold shock
A359_00620	COG2918	glutathione biosynthetic process
A359_00630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A359_00650	COG3118	belongs to the thioredoxin family
A359_00660	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A359_00670	COG0567	Dehydrogenase, E1 component
A359_00680	COG0508	dehydrogenase complex catalyzes the overall conversion of
A359_00690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A359_00750	COG0857	belongs to the CobB CobQ family
A359_00750	COG0280	phosphate acetyltransferase
A359_00760	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A359_00770	COG0542	response to heat
A359_00780	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A359_00830	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A359_00870	COG0047	phosphoribosylformylglycinamidine synthase activity
A359_00870	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A359_00880	COG0670	Belongs to the BI1 family
A359_00900	COG0513	Belongs to the DEAD box helicase family
A359_00910	COG2171	N-acyltransferase activity
A359_00920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A359_00950	COG0590	tRNA wobble adenosine to inosine editing
A359_00970	COG0556	nucleotide-excision repair
A359_00980	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A359_01000	COG0360	Binds together with S18 to 16S ribosomal RNA
A359_01020	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A359_01030	COG0359	binds to the 23S rRNA
A359_01060	COG1215	transferase activity, transferring glycosyl groups
A359_01110	COG0719	Fe-S assembly protein
A359_01120	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A359_01140	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
A359_01150	COG0482	sulfurtransferase activity
A359_01160	COG2915	High frequency lysogenization protein hflD homolog
A359_01170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A359_01190	COG0745	RESPONSE REGULATOR receiver
A359_01230	COG2920	part of a sulfur-relay system
A359_01250	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A359_01260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A359_01290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A359_01300	COG0583	DNA-binding transcription factor activity
A359_01310	COG0037	tRNA processing
A359_01320	COG0564	pseudouridine synthase activity
A359_01330	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A359_01340	COG0776	regulation of translation
A359_01350	COG0539	negative regulation of cytoplasmic translation
A359_01360	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A359_01380	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A359_01410	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A359_01420	COG1011	Hydrolase
A359_01440	COG0598	Magnesium transport protein CorA
A359_01450	COG0529	Catalyzes the synthesis of activated sulfate
A359_01460	COG2895	sulfate adenylyltransferase (ATP) activity
A359_01470	COG0175	sulfate reduction
A359_01480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A359_01480	COG1648	precorrin-2 dehydrogenase activity
A359_01490	COG0175	sulfate reduction
A359_01500	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A359_01510	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A359_01520	COG0720	synthase
A359_01530	COG0602	queuosine metabolic process
A359_01540	COG0148	phosphopyruvate hydratase activity
A359_01550	COG0504	CTP synthase activity
A359_01570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A359_01590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A359_01610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A359_01610	COG0072	phenylalanine-tRNA ligase activity
A359_01620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A359_01630	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A359_01640	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A359_01660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A359_01680	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
A359_01690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A359_01700	COG0328	RNA-DNA hybrid ribonuclease activity
A359_01710	COG2226	methyltransferase
A359_01720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A359_01730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A359_01740	COG2706	6-phosphogluconolactonase activity
A359_01760	COG0018	arginyl-trna synthetase
A359_01770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A359_01830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A359_01840	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A359_01850	COG1846	Transcriptional regulator
A359_01870	COG0728	peptidoglycan biosynthetic process
A359_01880	COG1770	oligopeptidase
A359_01940	COG1051	belongs to the nudix hydrolase family
A359_01960	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A359_01970	COG0284	orotidine-5'-phosphate decarboxylase activity
A359_02000	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A359_02000	COG0316	Belongs to the HesB IscA family
A359_02030	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A359_02040	COG0259	pyridoxamine-phosphate oxidase activity
A359_02060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A359_02080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A359_02110	COG3140	Belongs to the UPF0181 family
A359_02120	COG0017	Asparaginyl-tRNA synthetase
A359_02140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A359_02150	COG0302	gtp cyclohydrolase
A359_02160	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A359_02170	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A359_02180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A359_02190	COG0745	RESPONSE REGULATOR receiver
A359_02210	COG1045	serine acetyltransferase
A359_02220	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A359_02230	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
A359_02260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A359_02280	COG2814	Major facilitator Superfamily
A359_02350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A359_02360	COG0616	signal peptide processing
A359_02370	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A359_02380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A359_02390	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A359_02410	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A359_02440	COG0751	glycine-tRNA ligase activity
A359_02450	COG0752	glycyl-tRNA synthetase alpha subunit
A359_02480	COG0588	phosphoglycerate mutase activity
A359_02500	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A359_02510	COG1181	Belongs to the D-alanine--D-alanine ligase family
A359_02530	COG2877	3-deoxy-8-phosphooctulonate synthase activity
A359_02560	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A359_02570	COG0307	riboflavin synthase, alpha
A359_02580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A359_02600	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A359_02600	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A359_02620	COG0617	tRNA 3'-terminal CCA addition
A359_02660	COG1072	(Pantothenic acid kinase))
A359_02730	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A359_02740	COG0250	Participates in transcription elongation, termination and antitermination
A359_02750	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A359_02760	COG0081	regulation of translation
A359_02770	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A359_02780	COG0222	ribosome binding
A359_02790	COG0085	RNA polymerase activity
A359_02800	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A359_02820	COG0768	penicillin binding
A359_02830	COG0772	Belongs to the SEDS family
A359_02840	COG2921	Belongs to the UPF0250 family
A359_02850	COG0321	lipoyl(octanoyl) transferase activity
A359_02860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A359_02880	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A359_02890	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A359_02900	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A359_02910	COG0617	tRNA 3'-terminal CCA addition
A359_02920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A359_02960	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A359_02970	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
A359_02980	COG3264	Mechanosensitive ion channel
A359_02980	COG1511	domain protein
A359_02990	COG0688	phosphatidylethanolamine metabolic process
A359_03000	COG2166	iron-sulfur cluster assembly
A359_03010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A359_03020	COG0719	Fe-S assembly protein
A359_03030	COG0396	ATPase activity
A359_03040	COG0719	Fe-S assembly protein
A359_03050	COG0316	Belongs to the HesB IscA family
A359_03060	COG0033	Phosphoglucomutase
A359_03080	COG0203	ribosomal protein L17
A359_03100	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A359_03110	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A359_03120	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A359_03140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A359_03150	COG0201	protein transport
A359_03160	COG0200	Binds to the 23S rRNA
A359_03170	COG1841	ribosomal large subunit assembly
A359_03180	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A359_03190	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A359_03200	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A359_03210	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A359_03220	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A359_03230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A359_03240	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A359_03250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A359_03260	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A359_03270	COG0255	Belongs to the universal ribosomal protein uL29 family
A359_03280	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A359_03290	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A359_03310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A359_03320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A359_03330	COG0089	rRNA binding
A359_03340	COG0088	Forms part of the polypeptide exit tunnel
A359_03350	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A359_03360	COG0051	transcription antitermination factor activity, RNA binding
A359_03390	COG0113	porphobilinogen synthase activity
A359_03400	COG0442	prolyl-tRNA aminoacylation
A359_03420	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A359_03430	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
A359_03440	COG0237	dephospho-CoA kinase activity
A359_03470	COG0516	GMP reductase activity
A359_03480	COG0653	protein targeting
A359_03510	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
A359_03530	COG0849	cell division
A359_03550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A359_03560	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A359_03570	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A359_03580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A359_03590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A359_03600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A359_03620	COG0275	rRNA processing
A359_03650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A359_03670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A359_03680	COG0322	excinuclease ABC activity
A359_03740	COG4208	sulfate ABC transporter
A359_03750	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A359_03760	COG4150	thiosulfate binding
A359_03790	COG1253	flavin adenine dinucleotide binding
A359_03800	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A359_03800	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A359_03810	COG3715	PTS system
A359_03820	COG3716	PTS system mannose fructose sorbose family IID component
A359_03840	COG0288	reversible hydration of carbon dioxide
A359_03850	COG0586	Pfam SNARE associated Golgi protein
A359_03860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A359_03870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A359_03880	COG1671	Belongs to the UPF0178 family
A359_03890	COG1214	PFAM Peptidase M22, glycoprotease
A359_03900	COG1278	Cold shock
A359_03950	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A359_03980	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A359_03990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A359_04000	COG0167	dihydroorotate dehydrogenase activity
A359_04020	COG0354	folic acid binding
A359_04040	COG0513	Belongs to the DEAD box helicase family
A359_04060	COG0513	Belongs to the DEAD box helicase family
A359_04070	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A359_04080	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A359_04090	COG0049	tRNA binding
A359_04100	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A359_04110	COG2168	tRNA wobble position uridine thiolation
A359_04120	COG2923	Belongs to the DsrF TusC family
A359_04130	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A359_04140	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A359_04150	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A359_04160	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A359_04170	COG1587	Uroporphyrinogen-III synthase
A359_04230	COG0438	transferase activity, transferring glycosyl groups
A359_04240	COG1519	Transferase
A359_04260	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A359_04270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A359_04280	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A359_04290	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A359_04310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A359_04320	COG1067	ATP-dependent peptidase activity
A359_04340	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A359_04350	COG0009	L-threonylcarbamoyladenylate synthase
A359_04370	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
A359_04380	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A359_04390	COG0742	ribosomal rna small subunit methyltransferase
A359_04400	COG2095	MarC family integral membrane protein
A359_04410	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A359_04420	COG0142	geranyltranstransferase activity
A359_04430	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A359_04440	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A359_04460	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A359_04470	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A359_04480	COG0456	acetyltransferase
A359_04490	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
A359_04510	COG0425	Belongs to the sulfur carrier protein TusA family
A359_04530	COG0438	transferase activity, transferring glycosyl groups
A359_04580	COG0012	GTP binding
A359_04590	COG0193	aminoacyl-tRNA hydrolase activity
A359_04600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A359_04610	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A359_04620	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
A359_04670	COG0138	bifunctional purine biosynthesis protein purh
A359_04680	COG0151	Belongs to the GarS family
A359_04710	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A359_04730	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A359_04740	COG1509	lysine 2,3-aminomutase activity
A359_04750	COG0802	atpase or kinase
A359_04780	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A359_04790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A359_04800	COG1923	regulation of RNA biosynthetic process
A359_04820	COG0330	HflC and HflK could
A359_04830	COG0330	HflC and HflK could
A359_04840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A359_04850	COG0557	exoribonuclease II activity
A359_04860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A359_04890	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
A359_04900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A359_04910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A359_04920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A359_04930	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A359_04950	COG0195	Participates in both transcription termination and antitermination
A359_04960	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A359_04970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A359_04980	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A359_05000	COG0492	ferredoxin-NADP+ reductase activity
A359_05010	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A359_05020	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
A359_05030	COG0540	Belongs to the ATCase OTCase family
A359_05040	COG1132	(ABC) transporter
A359_05050	COG1663	tetraacyldisaccharide 4'-kinase activity
A359_05060	COG2835	tetraacyldisaccharide 4'-kinase activity
A359_05070	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
A359_05080	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A359_05090	COG3115	cell septum assembly
A359_05100	COG3785	DNA binding
A359_05110	COG2823	Periplasmic or secreted lipoprotein
A359_05120	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A359_05130	COG1466	dna polymerase III delta subunit
A359_05140	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
A359_05150	COG0495	leucyl-tRNA aminoacylation
A359_05170	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A359_05180	COG1185	polyribonucleotide nucleotidyltransferase activity
A359_05190	COG0513	Belongs to the DEAD box helicase family
A359_05210	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A359_05230	COG0756	dUTP diphosphatase activity
A359_05240	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A359_05280	COG0006	proline dipeptidase activity
A359_05290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A359_05300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A359_05320	COG2925	Exonuclease
A359_05340	COG0739	heme binding
A359_05360	COG0268	Binds directly to 16S ribosomal RNA
A359_05370	COG0484	heat shock protein binding
A359_05380	COG0443	Heat shock 70 kDa protein
A359_05390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A359_05410	COG0196	riboflavin kinase activity
A359_05420	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A359_05430	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A359_05450	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A359_05470	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
A359_05480	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A359_05490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A359_05500	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A359_05510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A359_05530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A359_05540	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A359_05550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A359_05560	COG0505	Belongs to the CarA family
A359_05570	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A359_05590	COG0306	phosphate transporter
A359_05610	COG0166	Belongs to the GPI family
A359_05630	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A359_05640	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A359_05650	COG0508	dehydrogenase complex catalyzes the overall conversion of
A359_05660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A359_05670	COG0071	Belongs to the small heat shock protein (HSP20) family
A359_05690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A359_05700	COG0527	aspartate kinase activity
A359_05710	COG0735	belongs to the Fur family
A359_05740	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A359_05750	COG4535	Mg2 and Co2 transporter CorC
A359_05770	COG0815	Transfers the fatty acyl group on membrane lipoproteins
A359_05800	COG1007	ATP synthesis coupled electron transport
A359_05810	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A359_05820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A359_05830	COG0713	ATP synthesis coupled electron transport
A359_05840	COG0839	Belongs to the complex I subunit 6 family
A359_05850	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A359_05860	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A359_05870	COG1034	ATP synthesis coupled electron transport
A359_05880	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A359_05890	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
A359_05900	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A359_05900	COG0649	NAD binding
A359_05910	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A359_05920	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A359_05940	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A359_05950	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
A359_05970	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A359_05990	COG0477	Major facilitator Superfamily
A359_06000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A359_06060	COG0625	glutathione transferase activity
A359_06070	COG2969	positive regulation of protein catabolic process
A359_06100	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A359_06130	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A359_06140	COG0285	dihydrofolate synthase activity
A359_06150	COG1286	toxin biosynthetic process
A359_06160	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A359_06170	COG0163	prenyltransferase activity
A359_06180	COG0326	Molecular chaperone. Has ATPase activity
A359_06190	COG0563	adenylate kinase activity
A359_06210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A359_06250	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A359_06260	COG0215	cysteine-tRNA ligase activity
A359_06270	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A359_06290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A359_06300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A359_06310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A359_06320	COG0811	peptide transport
A359_06330	COG0848	biopolymer transport protein
A359_06350	COG0823	Involved in the tonB-independent uptake of proteins
A359_06360	COG2885	chlorophyll binding
A359_06390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A359_06400	COG0358	DNA primase activity
A359_06420	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A359_06430	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A359_06440	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A359_06450	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A359_06460	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A359_06470	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A359_06490	COG0356	it plays a direct role in the translocation of protons across the membrane
A359_06500	COG0445	tRNA wobble uridine modification
A359_06510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A359_06520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A359_06530	COG3137	Salt-induced outer membrane protein
A359_06540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A359_06550	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
A359_06560	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A359_06580	COG0126	phosphoglycerate kinase activity
A359_06600	COG0584	glycerophosphoryl diester phosphodiesterase
A359_06620	COG0204	Acyl-transferase
A359_06640	COG2937	Belongs to the GPAT DAPAT family
A359_06660	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A359_06670	COG0594	ribonuclease P activity
A359_06680	COG0706	membrane insertase activity
A359_06690	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A359_06700	COG1074	ATP-dependent DNA helicase activity
A359_06730	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A359_06740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A359_06790	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A359_06800	COG0194	GDP metabolic process
A359_06810	COG1758	RNA polymerase activity
A359_06820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A359_06890	COG0233	cytoplasmic translational termination
A359_06900	COG0528	UMP kinase activity
A359_06910	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A359_06920	COG0052	Belongs to the universal ribosomal protein uS2 family
A359_06930	COG0024	Methionine aminopeptidase
A359_06940	COG0101	tRNA pseudouridine synthase activity
A359_06950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A359_06960	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A359_07010	COG0305	Participates in initiation and elongation during chromosome replication
A359_07060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A359_07070	COG2190	(PTS) system
A359_07090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A359_07100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A359_07110	COG0149	triose-phosphate isomerase activity
A359_07130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A359_07240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A359_07250	COG4591	ABC-type transport system involved in lipoprotein release permease component
A359_07260	COG1136	(ABC) transporter
A359_07270	COG4591	ABC-type transport system involved in lipoprotein release permease component
A359_07310	COG0488	(ABC) transporter
A359_07340	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A359_07360	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A359_07380	COG2927	DNA polymerase III (CHI subunit)
A359_07410	COG0859	PFAM glycosyl transferase family 9
A359_07420	COG0859	PFAM glycosyl transferase family 9
A359_07430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A359_07460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A359_07470	COG0463	Glycosyl transferase, family 2
A359_07480	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A359_07480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A359_07490	COG0726	polysaccharide deacetylase
A359_07500	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A359_07510	COG2076	Multidrug Resistance protein
A359_07520	COG2076	Multidrug Resistance protein
A359_07560	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A359_07580	COG0133	tryptophan synthase activity
A359_07590	COG0159	tryptophan synthase activity
A359_07620	COG0187	DNA topoisomerase II activity
A359_07700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A359_07720	COG0552	protein localization to endoplasmic reticulum
A359_07740	COG0481	GTPase activity
A359_07750	COG0681	Belongs to the peptidase S26 family
A359_07760	COG0571	ribonuclease III activity
A359_07780	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A359_07790	COG0736	holo-[acyl-carrier-protein] synthase activity
A359_07810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A359_07820	COG3105	Protein conserved in bacteria
A359_07830	COG0248	Ppx GppA phosphatase
A359_07840	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A359_07850	COG0469	pyruvate kinase activity
A359_07860	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A359_07880	COG0418	dihydroorotase activity
A359_07890	COG1530	ribonuclease E activity
A359_07910	COG0494	nUDIX hydrolase
A359_07920	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
A359_07940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A359_07950	COG0254	rRNA binding
A359_07960	COG0517	IMP dehydrogenase activity
A359_07960	COG0516	GMP reductase activity
A359_07980	COG0519	Catalyzes the synthesis of GMP from XMP
A359_07980	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A359_08000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A359_08020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A359_08060	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A359_08090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A359_08100	COG0803	Belongs to the bacterial solute-binding protein 9 family
A359_08120	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A359_08130	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A359_08150	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
A359_08150	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
A359_08190	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
A359_08210	COG0537	adenosine 5'-monophosphoramidase activity
A359_08230	COG0084	hydrolase, TatD family'
A359_08240	COG0470	DNA polymerase III
A359_08250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A359_08280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A359_08290	COG1028	Short-chain dehydrogenase reductase Sdr
A359_08310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A359_08320	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A359_08350	COG0729	surface antigen
A359_08360	COG2911	Protein conserved in bacteria
A359_08370	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A359_08380	COG0564	pseudouridine synthase activity
A359_08420	COG0483	inositol monophosphate 1-phosphatase activity
A359_08450	COG1218	3'(2'),5'-bisphosphate nucleotidase
A359_08460	COG1160	GTP binding
A359_08470	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A359_08480	COG0124	histidyl-tRNA synthetase
A359_08490	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
A359_08530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A359_08540	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A359_08550	COG0762	integral membrane protein
A359_08560	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
A359_08570	COG1194	a g-specific adenine glycosylase
A359_08590	COG2867	negative regulation of translational initiation
A359_08620	COG0316	Belongs to the HesB IscA family
A359_08640	COG0742	ribosomal rna small subunit methyltransferase
A359_08670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A359_08680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A359_08700	COG2226	methyltransferase
A359_08710	COG1322	Protein conserved in bacteria
A359_08730	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A359_08750	COG0006	proline dipeptidase activity
A359_08770	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A359_08780	COG1418	mRNA catabolic process
A359_08800	COG0336	Belongs to the RNA methyltransferase TrmD family
A359_08810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A359_08820	COG0228	four-way junction DNA binding
A359_08830	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A359_08850	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A359_08860	COG5007	Belongs to the BolA IbaG family
A359_08880	COG0517	IMP dehydrogenase activity
A359_08880	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A359_08890	COG3117	lipopolysaccharide transmembrane transporter activity
A359_08900	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A359_08910	COG1137	ATPase activity
A359_08930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A359_08940	COG1660	Displays ATPase and GTPase activities
A359_08950	COG0142	geranyltranstransferase activity
A359_08960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A359_08970	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A359_08980	COG2814	Major facilitator Superfamily
A359_08990	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A359_09000	COG1845	cytochrome c oxidase, subunit III
A359_09010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A359_09020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A359_09040	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A359_09060	COG0837	glucose binding
A359_09100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A359_09100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A359_09110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A359_09130	COG2890	protein-(glutamine-N5) methyltransferase activity
A359_09150	COG0628	permease
A359_09160	COG1528	Iron-storage protein
A359_09180	COG0189	ligase activity
A359_09220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A359_09230	COG0242	peptide deformylase activity
A359_09240	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A359_09260	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A359_09290	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A359_09330	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
A359_09340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A359_09350	COG1546	Belongs to the CinA family
A359_09360	COG3263	regulation of cellular component size
A359_09390	COG0501	Belongs to the peptidase M48B family
A359_09400	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
A359_09410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A359_09430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A359_09440	COG0575	Belongs to the CDS family
A359_09450	COG0750	zinc metalloprotease
A359_09460	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A359_09470	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
A359_09480	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A359_09490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A359_09500	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A359_09510	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A359_09530	COG0825	malonyl-CoA metabolic process
A359_09560	COG0205	6-phosphofructokinase activity
A359_09570	COG2814	Major facilitator Superfamily
A359_09580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A359_09610	COG0271	Belongs to the BolA IbaG family
A359_09620	COG0544	peptidyl-prolyl cis-trans isomerase activity
A359_09640	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A359_09650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A359_09660	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity