locus-tag class description N840_0001 ENOG4105CFH Aspartokinase N840_0003 ENOG4105D98 threonine synthase N840_0004 ENOG41062C6 Protein of unknown function (DUF2502) N840_0008 ENOG4108RIR Molybdenum cofactor biosynthesis protein N840_0009 ENOG4106HK8 GPR1 FUN34 yaaH family protein N840_0010 ENOG4108QUJ UPF0174 protein YaaW N840_0013 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) N840_0014 ENOG4108SER Transposase N840_0015 ENOG4105WI6 cell killing protein encoded within cryptic prophage N840_0018 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) N840_0019 ENOG41063Z6 transcriptional regulator, lysR family N840_0023 ENOG410647N response to DNA damage stimulus N840_0024 ENOG4105DTN riboflavin biosynthesis protein ribF N840_0027 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase N840_0031 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain N840_0032 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain N840_0033 ENOG4108XNW Transcriptional activatory protein CaiF N840_0035 ENOG4106YT9 Enoyl-CoA hydratase N840_0042 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase N840_0043 ENOG4105IBM Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster- containing protein N840_0044 ENOG4105C54 Major Facilitator superfamily N840_0047 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) N840_0052 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) N840_0053 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) N840_0054 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) N840_0056 ENOG4105D3G Pseudouridine synthase N840_0058 ENOG4105CQ2 DNA polymerase N840_0059 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase N840_0060 ENOG4105CAC Catalyzes the conversion of L-arabinose to L-ribulose (By similarity) N840_0061 ENOG4105EF1 ribulokinase N840_0062 ENOG41063TF transcriptional regulator (AraC N840_0063 ENOG4108KF1 Membrane N840_0064 ENOG4107T0D ABC, transporter N840_0065 ENOG4106SMU thiamine transporter membrane protein N840_0066 ENOG4105DP9 ABC transporter N840_0067 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) N840_0070 ENOG4105S8Q sugar efflux transporter N840_0073 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) N840_0076 ENOG41064T2 transcriptional regulator, lysR family N840_0077 ENOG4105C7K acetolactate synthase N840_0078 ENOG4108ZP8 Acetolactate synthase small subunit N840_0079 ENOG4107B7Y DNA-binding transcriptional regulator FruR N840_0080 ENOG4108V6E Cell division protein mraZ N840_0082 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) N840_0083 ENOG4105CJN penicillin-binding protein N840_0084 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) N840_0085 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) N840_0087 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) N840_0088 ENOG4105CNI cell division protein FtsW N840_0091 ENOG4105CPF Cell wall formation (By similarity) N840_0092 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) N840_0093 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) N840_0094 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) N840_0098 ENOG4105M6F mutator MutT protein N840_0101 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) N840_0103 ENOG4105D7Q type ii secretion system N840_0104 ENOG4107QHF type ii secretion system protein e N840_0105 ENOG4108ZUW Major pilin subunit N840_0106 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase N840_0107 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase N840_0108 ENOG4106A72 regulatory protein AmpE N840_0109 ENOG4105C85 amino acid N840_0110 ENOG41073TP transcriptional regulator N840_0111 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) N840_0112 ENOG4107QSN dihydrolipoamide acetyltransferase N840_0113 ENOG4107QN2 dihydrolipoyl dehydrogenase N840_0114 ENOG4108NST exported protein N840_0115 ENOG4107QIJ Aconitate hydratase 2 N840_0119 ENOG4108ZRK uncharacterized protein yacC N840_0120 ENOG4105E3B Multicopper oxidase N840_0121 ENOG4105DZG Dehydrogenase N840_0122 ENOG4108UGV hypoxanthine phosphoribosyltransferase N840_0123 ENOG41077A9 carbonic anhydrase N840_0124 ENOG4105DA5 (ABC) transporter N840_0125 ENOG4105E3A (ABC) transporter N840_0126 ENOG4108YTN IIa component N840_0127 ENOG4107BJW polysaccharide deacetylase N840_0129 ENOG4108A32 Transposase N840_0132 ENOG4105P0Q fimbrial-like protein YadC N840_0133 ENOG4105SN2 fimbrial-like adhesin protein N840_0134 ENOG4105SYG Fimbrial protein N840_0135 ENOG4108XEY fimbrial-like adhesin protein N840_0136 ENOG4105CW0 outer membrane usher protein N840_0137 ENOG4108VEV chaperone N840_0139 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase N840_0140 ENOG4105DJ0 Poly(A) Polymerase N840_0142 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters N840_0144 ENOG4107XID 2'-5' rna ligase N840_0145 ENOG4105CQ7 ATP-dependent helicase N840_0146 ENOG4105BZ4 penicillin-binding protein N840_0147 ENOG4105E0K tonB-dependent siderophore receptor N840_0148 ENOG4105E0A ABC, transporter N840_0149 ENOG4105J76 Periplasmic binding protein N840_0150 ENOG4105S6R Iron-hydroxamate transporter permease subunit N840_0154 ENOG4105EN6 Membrane N840_0155 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) N840_0158 ENOG4105C0H protease N840_0161 ENOG4105DIN metallophosphoesterase N840_0164 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) N840_0170 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) N840_0171 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) N840_0172 ENOG4105KNE Phosphatidate cytidylyltransferase N840_0173 ENOG4105DZP Membrane-associated zinc metalloprotease N840_0175 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) N840_0176 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) N840_0181 ENOG4105C0B DNA polymerase III (alpha subunit) N840_0183 ENOG4105CXN decarboxylase N840_0184 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase N840_0185 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) N840_0186 ENOG4105M1T rho-binding antiterminator N840_0188 ENOG4108VWS Yaeq family N840_0189 ENOG4108YZN class I peptide chain release factor N840_0190 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion N840_0191 ENOG4108UY0 (LipO)protein N840_0193 ENOG4108R96 Methyltransferase, YaeB family N840_0194 ENOG4108R8X outer membrane lipoprotein N840_0195 ENOG4105D01 (LipO)protein N840_0196 ENOG4108UMI ABC transporter, permease N840_0197 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) N840_0198 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase N840_0205 ENOG4105CV8 reductase N840_0206 ENOG4105HEI LysR family (Transcriptional regulator N840_0208 ENOG4105F2W methyltransferase N840_0209 ENOG4105E9H Lytic Murein transglycosylase N840_0210 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) N840_0211 ENOG4105D1A Methyltransferase N840_0213 ENOG4107RZZ dna polymerase iii epsilon subunit N840_0215 ENOG410600K aminopeptidase N840_0219 ENOG4105CZ7 nitrilase cyanide hydratase and apolipoprotein n-acyltransferase N840_0220 ENOG4108WN0 inhibitor of vertebrate lysozyme N840_0221 ENOG4107QPN acyl-Coa dehydrogenase N840_0223 ENOG4105E7A Glutamine amidotransferase N840_0224 ENOG4105F7V ErfK ybiS ycfS ynhG family protein N840_0225 ENOG4105VXN addiction module toxin, RelE StbE family N840_0226 ENOG4105QHH Antitoxin component of a toxin-antitoxin (TA) module. A labile antitoxin that counteracts the effect of the YafQ toxin. YafQ and DinJ together bind their own promoter, and by analogy to other TA modules probably repress its expression N840_0227 ENOG4108YS0 lipoprotein YafL N840_0228 ENOG4108UK5 Transposase N840_0231 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) N840_0232 ENOG4105UG9 Antitoxin of the YafO-YafN toxin-antitoxin system N840_0233 ENOG41065DM this blockage is overcome by subsequent expression of antitoxin YafN. Overexpression causes cleavage of a number of mRNAs in a ribosome-dependent fashion. YafO binding to the 50S ribosomal subunit in the translation complex induces mRNA cleavage 3' to the region protected by the ribosome N840_0234 ENOG4108HYG acetyltransferase N840_0237 ENOG4105CIN aminoacyl-histidine dipeptidase N840_0241 ENOG4105FCK Membrane N840_0246 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures N840_0248 ENOG4105ZS6 Protein of unknown function (DUF987) N840_0249 ENOG4108XS9 dna repair protein N840_0250 ENOG4106549 Antirestriction protein N840_0251 ENOG4106ZN7 UPF0401 protein YkfF N840_0252 ENOG4106J9S Prophage N840_0256 ENOG4106H6R UPF0380 protein N840_0257 ENOG4108MXD gtp-binding protein N840_0258 ENOG4108PZW LysR family Transcriptional regulator N840_0260 ENOG4105F9F transposase N840_0263 ENOG4105F2I Transposase N840_0264 ENOG4108IQI permease N840_0265 ENOG4107QK5 Homocysteine s-methyltransferase N840_0266 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) N840_0268 ENOG4108MBK is1 orf2 N840_0274 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) N840_0275 ENOG4105C01 Dihydroxy-acid dehydratase N840_0276 ENOG4105CT4 transporter N840_0277 ENOG4105DSG hydrolase family 43 N840_0278 ENOG4107HP6 Transcriptional regulator N840_0279 ENOG4105DBV ornithine carbamoyltransferase N840_0281 ENOG4108MBK is1 orf2 N840_0284 ENOG4105JXR Protein of unknown function (DUF3296) N840_0285 ENOG410693A DNA-binding protein N840_0286 ENOG4106GND N840_0287 ENOG410792U CP4-6 prophage N840_0288 ENOG41067CV Integrase N840_0292 ENOG4107XAN XdhC and CoxI family N840_0293 ENOG4105C7W Xanthine dehydrogenase N840_0294 ENOG4105DIP Molybdopterin dehydrogenase FAD-binding N840_0295 ENOG4107XKX isoquinoline 1-oxidoreductase, alpha subunit N840_0296 ENOG4105R3P Inner membrane protein yagU N840_0297 ENOG4105PI0 Ferredoxin N840_0298 ENOG4108UD7 cell wall organization N840_0299 ENOG4106PYX Receptor N840_0300 ENOG4108N3D putative enzyme N840_0302 ENOG4108GWT fimbrillin MatB N840_0303 ENOG4106JB4 Represses expression of the flagellar master operon flhDC, and consequently prevents flagellum biosynthesis and motility. Acts by binding to the regulatory region of the flhDC operon N840_0306 ENOG4105NRA 50s ribosomal protein l31 type b N840_0310 ENOG41090WB Transposase is3 is911 N840_0314 ENOG4108KBJ Inner membrane protein YkgB N840_0315 ENOG41066GK UPF0379 protein ykgI N840_0316 ENOG4107QN2 dihydrolipoyl dehydrogenase N840_0317 ENOG4108K01 transcriptional regulator N840_0318 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) N840_0319 ENOG4107QR9 Iron-sulfur cluster binding protein N840_0320 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) N840_0322 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) N840_0323 ENOG4105C26 Dehydrogenase N840_0324 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) N840_0325 ENOG4105C94 Transporter N840_0326 ENOG4105BZU Histidine kinase N840_0327 ENOG4108NUU Transcriptional regulator N840_0328 ENOG4105SZ2 membrAne N840_0329 ENOG4107SNB ankyrin repeat protein YahD N840_0331 ENOG4107R1Q Membrane protein FdrA N840_0332 ENOG4107REC cytoplasmic protein N840_0333 ENOG4105C5B carbamate kinase N840_0334 ENOG4105DZC cytosine deaminase N840_0335 ENOG4105DQ4 alcohol dehydrogenase N840_0338 ENOG4105E82 cytochrome subunit of dehydrogenase N840_0339 ENOG4105TDT uncharacterized protein yahO N840_0340 ENOG4108JU7 Transcriptional regulator N840_0341 ENOG4105CR4 methylisocitrate lyase N840_0342 ENOG4105BZN citrate synthase N840_0343 ENOG4105DXD 2-methylcitrate dehydratase N840_0344 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) N840_0345 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin N840_0346 ENOG4105DZC cytosine deaminase N840_0347 ENOG4105DND Transcriptional regulator N840_0348 ENOG4107B2H carbonic anhydrase N840_0349 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) N840_0350 ENOG4105DJ2 Major Facilitator Superfamily N840_0351 ENOG4108UW5 maltose o-acetyltransferase N840_0352 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) N840_0354 ENOG4105ETE Transcriptional regulator (LacI family N840_0355 ENOG4108K2P TRANSCRIPTIONal N840_0356 ENOG4105E2Q 3-(3-hydroxy-phenyl)propionate hydroxylase N840_0357 ENOG4105MI0 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity) N840_0359 ENOG4105IKQ hydratase N840_0362 ENOG4108SC4 )-transporter N840_0363 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme N840_0364 ENOG4105C4W S-formylglutathione hydrolase N840_0365 ENOG4108I9Z alcohol dehydrogenase N840_0367 ENOG4105SRB Uncharacterized protein yaiO N840_0369 ENOG4108ZQS transposase N840_0370 ENOG4108MVM Transposase N840_0371 ENOG4108PBI Polysaccharide metabolism N840_0372 ENOG4107W19 lmbE family N840_0373 ENOG4106FTQ Taurine ABC transporter, periplasmic N840_0374 ENOG4108IY8 ABC, transporter N840_0375 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component N840_0376 ENOG4105E2B Taurine dioxygenase N840_0377 ENOG4105D52 delta-aminolevulinic acid dehydratase N840_0380 ENOG41090WB Transposase is3 is911 N840_0381 ENOG4108PNB DNA-binding transcriptional regulator N840_0382 ENOG4107R6D beta-lactam binding protein AmpH N840_0383 ENOG4108DQG in Escherichia coli SbmA is involved in uptake of microcin J25 N840_0384 ENOG4107QS8 (LipO)protein N840_0385 ENOG4105FR5 inner membrane protein YaiY N840_0386 ENOG4105UNH Membrane N840_0387 ENOG4105CPF Cell wall formation (By similarity) N840_0389 ENOG4105G6Z alkaline phosphatase N840_0390 ENOG4105VIF phosphate starvation-inducible protein N840_0391 ENOG4105BZU Histidine kinase N840_0392 ENOG4105II7 pyrroline-5-carboxylate reductase N840_0395 ENOG4105SS3 N840_0396 ENOG4105HBA AroM protein N840_0400 ENOG4105DKQ ROK family N840_0401 ENOG4105F27 Major Facilitator N840_0402 ENOG4105EYH Exonuclease N840_0403 ENOG4107RH8 nuclease SbcCD subunit D N840_0404 ENOG4105CK6 Two component transcriptional regulator (Winged helix family N840_0405 ENOG4105BZU Histidine kinase N840_0406 ENOG4105CWM branched-chain amino acid transport system II carrier protein N840_0407 ENOG4105C85 amino acid N840_0408 ENOG4107R28 alpha amylase, catalytic region N840_0412 ENOG4105VIE preprotein translocase, subunit YajC N840_0413 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) N840_0414 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) N840_0415 ENOG4105N1F Hnh endonuclease N840_0416 ENOG4105DRB nucleoside-specific channel-forming protein N840_0417 ENOG4108KIC (LipO)protein N840_0419 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) N840_0420 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) N840_0422 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) N840_0423 ENOG4108ZAI phosphatidylglycerophosphatase a N840_0424 ENOG4105CPC Aldo Keto reductase N840_0426 ENOG4105CTB Polyprenyl synthetase N840_0429 ENOG4107S0N DJ-1 family N840_0430 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) N840_0432 ENOG4107RDB Major Facilitator N840_0434 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) N840_0435 ENOG4105CCU oxidase (Subunit III) N840_0436 ENOG4105BZ9 Cytochrome C oxidase, subunit I N840_0437 ENOG4105E2S oxidase) subunit II N840_0438 ENOG4105EYM Major Facilitator superfamily N840_0439 ENOG4105IEY (LipO)protein N840_0440 ENOG4105M85 Bola protein N840_0444 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) N840_0445 ENOG4105K70 DNA-binding protein N840_0446 ENOG4105EIN peptidylprolyl cis-trans isomerase N840_0447 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein N840_0448 ENOG4108TGP Thioesterase superfamily protein N840_0450 ENOG4108NFA extracellular solute-binding protein N840_0452 ENOG4108XM1 transcriptional regulator AsnC family N840_0453 ENOG4105BZ1 (ABC) transporter N840_0454 ENOG4105BZ1 (ABC) transporter N840_0455 ENOG4108YZA Nitrogen regulatory protein pii N840_0456 ENOG4105BZU Histidine kinase N840_0457 ENOG4105C29 acyl-CoA thioesterase N840_0458 ENOG4108MNP Glycoprotein polysaccharide metabolism N840_0459 ENOG41080UX Methyltransferase N840_0461 ENOG4105KCV RNA signal recognition particle 4.5S RNA N840_0462 ENOG41066DG (EAL) domain protein N840_0463 ENOG4105GSJ Inner membrane protein ylaC N840_0464 ENOG4108UW5 maltose o-acetyltransferase N840_0465 ENOG4105KF5 hemolysin expression-modulating protein N840_0466 ENOG4108UKR Biofilm formation regulator YbaJ N840_0467 ENOG4105BZS acriflavin resistance protein N840_0468 ENOG4105C1P efflux transporter, rnd family, mfp subunit N840_0469 ENOG4108IG5 Transcriptional regulator N840_0470 ENOG4105EGS Mechanosensitive ion channel N840_0471 ENOG4106428 Protein of unknown function (DUF2496) N840_0472 ENOG4108URS primosomal replication protein n'' N840_0473 ENOG4105WD1 Membrane N840_0475 ENOG4107QMP dna polymerase iii subunits gamma and tau N840_0478 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) N840_0482 ENOG4107RE1 Inosine-guanosine kinase N840_0483 ENOG4105CKD glutathione-regulated potassium-efflux system protein N840_0484 ENOG4105EU0 Major facilitator Superfamily N840_0485 ENOG4105CGH 5'-nucleotidase N840_0486 ENOG4108Z66 YbaK ebsC protein N840_0488 ENOG4105MBR gumn family N840_0489 ENOG41081XE plasmid maintenance system antidote protein, xre family N840_0490 ENOG4105C59 p-type ATPase N840_0491 ENOG4105CSV Glutaminase N840_0492 ENOG4107RY6 amino acid N840_0493 ENOG4108Z6Z Transcriptional regulator N840_0494 ENOG4105G5H Membrane N840_0495 ENOG4107QX8 SPFH domain, Band 7 family protein N840_0496 ENOG41083J0 (ABC) transporter N840_0497 ENOG4105C4B ABC transporter, permease N840_0498 ENOG4107QR8 Thioredoxin N840_0499 ENOG4105E1F short-chain dehydrogenase reductase N840_0500 ENOG4108UJV acyl-CoA thioesterase i N840_0501 ENOG4108I0Y (ABC) transporter N840_0502 ENOG4105CV6 ABC transporter, permease N840_0503 ENOG4105CNA YD repeat protein N840_0510 ENOG4107653 Transcriptional regulator N840_0512 ENOG4108N16 Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region N840_0513 ENOG41060W2 glyoxylate carboligase N840_0514 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) N840_0515 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase N840_0516 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease N840_0518 ENOG4105DTE Xanthine uracil vitamin C permease N840_0519 ENOG4105BZW Glycerate kinase N840_0520 ENOG4105S0E allantoin catabolism protein N840_0521 ENOG4105CE7 Amidase, hydantoinase carbamoylase family N840_0522 ENOG4105DG4 malate L-lactate dehydrogenase N840_0523 ENOG4107R1Q Membrane protein FdrA N840_0525 ENOG4105G5A Protein of unknown function (DUF2877) N840_0526 ENOG4105C5B carbamate kinase N840_0527 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit N840_0528 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) N840_0530 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) N840_0532 ENOG4105S2T inner membrane protein YbcI N840_0533 ENOG4105WQ3 Rna-binding protein N840_0535 ENOG4108WDE Fimbrial protein N840_0536 ENOG4108AF8 Chaperone N840_0537 ENOG4105CW0 outer membrane usher protein N840_0538 ENOG4108M66 Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity) N840_0539 ENOG4108ZI2 Fimbrial protein N840_0540 ENOG4108Q9V regulatoR N840_0542 ENOG4108KU3 Integrase N840_0547 ENOG41090WB Transposase is3 is911 N840_0549 ENOG410814C multidrug resistance protein N840_0550 ENOG4107TII Recombinase N840_0551 ENOG4108V1U phospholipid-binding protein N840_0552 ENOG4108UQN AraC family transcriptional regulator N840_0554 ENOG4108V2F protein ybcN in lambdoid DLP12 prophage regi N840_0555 ENOG410757E Protein NinE homolog from lambdoid prophage DLP12 N840_0556 ENOG4105RWQ Protein of unknown function (DUF1364) N840_0559 ENOG4105HRS Antitermination protein N840_0561 ENOG4105F2I Transposase N840_0562 ENOG4105QFS Lysis protein S homolog from lambdoid prophage N840_0563 ENOG4105KUS lysozyme N840_0564 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 N840_0566 ENOG4105QYK bacteriophage lambda Bor protein homolog N840_0569 ENOG4106YSC N840_0570 ENOG4105FKG DNA packaging protein N840_0575 ENOG4108MIW Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions N840_0576 ENOG4108NC2 Outer membrane protease N840_0579 ENOG4105QUW N840_0580 ENOG41090FC Bacteriophage N4 receptor, outer membrane subunit N840_0581 ENOG410802X bacteriophage n4 adsorption protein b N840_0582 ENOG4105GR3 Histidine kinase N840_0583 ENOG4105CK6 Two component transcriptional regulator (Winged helix family N840_0584 ENOG4105ENJ RND efflux system, outer membrane lipoprotein N840_0585 ENOG410624V efflux system protein N840_0586 ENOG4105EP1 Efflux transporter rnd family, mfp subunit N840_0587 ENOG4108IJF Heavy metal efflux pump, CzcA N840_0588 ENOG4105C85 amino acid N840_0589 ENOG4105CUY Mechanosensitive ion channel N840_0590 ENOG4108RCM Nitroreductase N840_0591 ENOG4105MSB protein, conserved in bacteria N840_0592 ENOG4105WQ6 Membrane N840_0595 ENOG4107635 Hok Gef family protein N840_0596 ENOG4108SER Transposase N840_0597 ENOG4108TSE Transferase N840_0598 ENOG4107RNH Outer membrane receptor FepA N840_0599 ENOG4105E93 esterase N840_0600 ENOG41085A6 mbth domain-containing protein N840_0601 ENOG4105C0W non-ribosomal peptide synthetase N840_0602 ENOG4108QY5 Ferric enterobactin transport protein N840_0603 ENOG4105E0A ABC, transporter N840_0604 ENOG4105TVJ transport system, permease N840_0605 ENOG4105DQ5 transport system permease protein N840_0607 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein N840_0608 ENOG4105E4F Isochorismate synthase N840_0609 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase N840_0610 ENOG4105WQI isochorismatase N840_0611 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase N840_0612 ENOG4108TZA Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity) N840_0613 ENOG4105D22 carbon starvation protein N840_0614 ENOG4105VCD cytoplasmic protein N840_0615 ENOG4107SCQ Iron-containing alcohol dehydrogenase N840_0616 ENOG4105CHM Aminotransferase N840_0617 ENOG4105GTN ParB Domain Protein Nuclease N840_0618 ENOG4105BZV Phosphoadenosine phosphosulfate reductase N840_0619 ENOG4105DQS Transcriptional regulator N840_0620 ENOG4108KHN disulfide isomerase, thiol-disulfide oxidase N840_0621 ENOG4105D3R alkyl hydroperoxide reductase N840_0622 ENOG4108JU3 Alkyl hydroperoxide reductase N840_0623 ENOG4108U51 Universal stress protein N840_0624 ENOG4105E2A Dehydrogenase N840_0625 ENOG4105NXH GreA GreB family elongation factor N840_0626 ENOG4105KTS ribonuclease N840_0627 ENOG4107QPK )-transporter N840_0630 ENOG4105CHY citrate lyase, alpha N840_0631 ENOG4105CI0 Citrate lyase N840_0633 ENOG4105DUA (citrate (pro-3S)-lyase ligase N840_0634 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism N840_0635 ENOG4106YYS transcriptional regulatory protein N840_0636 ENOG4105CEE C4-dicarboxylate transporter N840_0637 ENOG41079UR PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity) N840_0638 ENOG4105VEQ Cold shock protein N840_0641 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) N840_0643 ENOG41064T2 transcriptional regulator, lysR family N840_0646 ENOG4105DZ1 carboxypeptidase N840_0647 ENOG4105K6T rare lipoprotein A N840_0648 ENOG4105CNI cell division protein FtsW N840_0649 ENOG4105CJN penicillin-binding protein N840_0651 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) N840_0652 ENOG4108TGR phosphatase N840_0654 ENOG4105DJF DNA polymerase III, delta' subunit N840_0657 ENOG4107PAI alpha helical protein N840_0659 ENOG41069CF Protein of unknown function (DUF1266) N840_0660 ENOG4105QFC Hsc56 co-chaperone of HscC N840_0661 ENOG4107JFD Sel1 repeat N840_0662 ENOG41069CF Protein of unknown function (DUF1266) N840_0663 ENOG4105QFC Hsc56 co-chaperone of HscC N840_0664 ENOG4105F7F Chaperone N840_0666 ENOG4105CDA abc transporter atp-binding protein N840_0667 ENOG4105DRP amino acid AbC transporter N840_0668 ENOG4105EAD ABC transporter N840_0669 ENOG4107RP9 extracellular solute-binding protein, family 3 N840_0670 ENOG4105F2I Transposase N840_0671 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) N840_0672 ENOG4108JU5 Magnesium and cobalt efflux protein N840_0674 ENOG4105C9A Phoh family N840_0676 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family N840_0684 ENOG4105CAQ asparagine synthetase N840_0685 ENOG4105D4U had-superfamily hydrolase, subfamily iia N840_0686 ENOG4105E2R ROK family N840_0687 ENOG4105CE4 GlcNAc 6-P deacetylase N840_0689 ENOG4105CI1 PTS System N840_0692 ENOG4105GX6 (LipO)protein N840_0693 ENOG41090R7 Ferric uptake N840_0695 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) N840_0696 ENOG4105NNH LexA regulated protein N840_0697 ENOG4105EV9 Alpha Beta Hydrolase N840_0698 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) N840_0699 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 N840_0703 ENOG4105D5Q Arginine ornithine antiporter N840_0704 ENOG4105CXN decarboxylase N840_0706 ENOG4105EEX Two component transcriptional regulator (Winged helix family N840_0712 ENOG4105XIQ Protein of unknown function (DUF2517) N840_0713 ENOG4105CNA YD repeat protein N840_0714 ENOG41079JQ Membrane N840_0716 ENOG4106R09 N840_0719 ENOG410600T transposase N840_0720 ENOG4107SEY Conserved Protein N840_0721 ENOG4105CVP deoxyribo-dipyrimidine photolyase N840_0722 ENOG4105DUX Transporter N840_0723 ENOG4107QNR UPF0135 protein N840_0724 ENOG4105P4J Allophanate hydrolase, subunit 1 N840_0725 ENOG4107R7A Allophanate hydrolase subunit 2 N840_0728 ENOG4108KK1 membrane protein AbrB duplication N840_0729 ENOG4108MY7 Fimbrial N840_0730 ENOG4108TTM chaperone N840_0731 ENOG4106PG1 outer membrane usher protein N840_0732 ENOG4106UBK fimbrial-like adhesin protein N840_0733 ENOG4105BZN citrate synthase N840_0734 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit N840_0735 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein N840_0736 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) N840_0737 ENOG4105E33 succinate dehydrogenase N840_0738 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 N840_0739 ENOG4105C7S Dehydrogenase N840_0741 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha N840_0742 ENOG4105FDP GntR family transcriptional regulator N840_0743 ENOG4105DM4 PTS System N840_0744 ENOG4105C8I hydrolase, family 38 N840_0745 ENOG4105C4M (Ubiquinol oxidase) subunit I N840_0746 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii N840_0748 ENOG4105KJB cyd operon protein YbgE N840_0749 ENOG4107YD3 Thioesterase N840_0750 ENOG4105E02 MotA TolQ exbB proton channel N840_0751 ENOG4105M8F Biopolymer transport protein exbD tolR N840_0752 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA N840_0754 ENOG4105KCK Peptidoglycan-associated lipoprotein N840_0755 ENOG4105UFD tol-pal system protein YbgF N840_0764 ENOG4106Z1T Nicotinamide Mononucleotide Transporter N840_0765 ENOG4105PGM cation diffusion facilitator family transporter N840_0766 ENOG4105JND homeobox protein N840_0767 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) N840_0769 ENOG4105F0Z galactose-1-phosphate uridylyltransferase N840_0770 ENOG4105CMR udp-glucose 4-epimerase N840_0771 ENOG4105DKW ABC transporter N840_0772 ENOG4105F4R Transcriptional regulator mode N840_0773 ENOG410680R Protein of unknown function (DUF2592) N840_0774 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein N840_0775 ENOG4105E0C molybdate abc transporter N840_0776 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) N840_0777 ENOG4108K4B hydrolase N840_0779 ENOG4105F04 LysR family Transcriptional regulator N840_0780 ENOG4105C7F AcnD-accessory protein PrpF N840_0781 ENOG4107QPK )-transporter N840_0782 ENOG4107QM5 aconitate hydratase N840_0783 ENOG4105NBR Pectinesterase N840_0784 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) N840_0785 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) N840_0786 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) N840_0788 ENOG4105CHW UPF0052 protein N840_0790 ENOG4108RIR Molybdenum cofactor biosynthesis protein N840_0792 ENOG4105M00 molybdopterin converting factor, subunit 1 N840_0793 ENOG4108ZAF Molybdopterin N840_0794 ENOG4105HFZ Membrane N840_0795 ENOG410733J conserved inner membrane protein N840_0796 ENOG4107UXM Membrane N840_0797 ENOG4105DZQ phospholipase D Transphosphatidylase N840_0798 ENOG4105X23 Endonuclease Exonuclease phosphatase N840_0799 ENOG4105I9U inner membrane protein ybhQ N840_0800 ENOG4107QWP ABC-2 type transporter N840_0801 ENOG4107QWP ABC-2 type transporter N840_0802 ENOG4105CJ1 ABC, transporter N840_0804 ENOG4107MVR Transcriptional regulator N840_0805 ENOG4105C1J atp-dependent rna helicase N840_0806 ENOG4108UV1 cellular component movement N840_0807 ENOG4105DVT helicase N840_0808 ENOG4108MTB glycosyl transferase family N840_0809 ENOG4105DG4 malate L-lactate dehydrogenase N840_0810 ENOG4105VR4 UPF0379 protein ybiJ N840_0811 ENOG4105KSC Transcriptional regulator, TraR DksA family N840_0813 ENOG4108IU3 tonb-dependent siderophore receptor N840_0814 ENOG4105ZY9 UPF0379 protein ybiM N840_0816 ENOG4105D8X mechanosensitive ion channel N840_0817 ENOG4105CDA abc transporter atp-binding protein N840_0818 ENOG4105E5Q amino acid AbC transporter N840_0819 ENOG4107R0W ABC transporter N840_0821 ENOG4107AQZ Membrane N840_0822 ENOG4108T1M outer membrane protein x N840_0823 ENOG4108I6E Sulfatase N840_0825 ENOG4105KST dependent repressor N840_0826 ENOG4105F4P )-transporter N840_0827 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein N840_0828 ENOG4105C5H ABC transporter N840_0829 ENOG41072TH Protein of unknown function (DUF1479) N840_0830 ENOG4108HCJ Hydrolase N840_0831 ENOG4105C6N Formate acetyltransferase N840_0832 ENOG4105F1A Pyruvate formate-lyase N840_0833 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) N840_0834 ENOG4105D06 uba thif-type nad fad binding protein N840_0835 ENOG4105CVM Molybdenum cofactor synthesis domain protein N840_0836 ENOG4105D44 asparaginase N840_0837 ENOG4108JQ6 ABC transporter N840_0838 ENOG4105DEF Extracellular solute-binding protein, family 5 N840_0840 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component N840_0841 ENOG4105BZU Histidine kinase N840_0842 ENOG41064RH membrane protein YliF N840_0844 ENOG4105UFT Represses biofilm formation in M9C glu and LB glu media but not in M9C and LB media. Seems to act as a global regulator of several genes involved in catabolite repression and stress response and regulation of the uptake and export of signaling pathways. Could be involved the regulation of indole as well as uptake and export of AI-2 through a cAMP-dependent pathway N840_0845 ENOG4105D8V Glucose sorbosone dehydrogenase N840_0846 ENOG4108TGY Glutathione S-transferase N840_0847 ENOG4105DZ1 carboxypeptidase N840_0848 ENOG4107FB0 transcriptional regulator DeoR family N840_0849 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase N840_0850 ENOG4107QF7 multi-drug N840_0852 ENOG4108HCJ Hydrolase N840_0853 ENOG4106UW1 Major Facilitator superfamily N840_0854 ENOG4108RFG Tetr family transcriptional regulator N840_0857 ENOG4105GWF inner membrane protein YbjM N840_0858 ENOG41090BQ Glutaredoxin N840_0859 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress N840_0860 ENOG4108DBC nitroreductase N840_0862 ENOG4108RMJ sensory transduction regulator N840_0863 ENOG4107RUE extracellular solute-binding protein family 1 N840_0864 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) N840_0865 ENOG4105F38 ABC transporter, permease N840_0866 ENOG4105D38 putrescine abc transporter N840_0867 ENOG4105RBQ inner membrane protein ybjO N840_0869 ENOG4106TNF Periplasmic binding protein N840_0870 ENOG4105DMR ABC, transporter N840_0871 ENOG4105GBT ABC transporter N840_0872 ENOG4106PMH Extracellular solute-binding protein family 3 N840_0873 ENOG4105E5Z arginine transporter ATP-binding subunit N840_0874 ENOG41064MM (LipO)protein N840_0876 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase N840_0877 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase N840_0878 ENOG4105CGD Nad-dependent epimerase dehydratase N840_0879 ENOG4105C5W Aldolase N840_0880 ENOG4105C7K acetolactate synthase N840_0881 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) N840_0883 ENOG4105DWU Membrane N840_0884 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) N840_0885 ENOG4105CPB ATP-dependent endonuclease of the OLD family N840_0886 ENOG4108MJ5 VirK protein N840_0887 ENOG4105DJY efflux transporter, rnd family, mfp subunit N840_0888 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) N840_0889 ENOG4105VEQ Cold shock protein N840_0891 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit N840_0893 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) N840_0895 ENOG4108JJ8 (ABC) transporter N840_0896 ENOG4108JJ9 ABC, transporter N840_0897 ENOG4105C3M thioredoxin reductase N840_0898 ENOG4105EW9 transcriptional regulator AsnC family N840_0899 ENOG4105CNU cell division protein FtsK N840_0901 ENOG4105D1H recombination factor protein RarA N840_0903 ENOG4107QY8 reductase N840_0904 ENOG4105QAX Iron-sulfur N840_0905 ENOG4107KGK dmso reductase anchor subunit N840_0906 ENOG4105CHJ isochorismatase hydrolase N840_0908 ENOG4105E5D amino acid N840_0909 ENOG410642W LysR family Transcriptional regulator N840_0910 ENOG4108X0B nad(p)h dehydrogenase (quinone) N840_0911 ENOG4105F1A Pyruvate formate-lyase N840_0912 ENOG4105C6N Formate acetyltransferase N840_0913 ENOG4105TMB Formate nitrite transporter N840_0914 ENOG4105DDY UPF0142 protein ycaO N840_0915 ENOG4107VMU Membrane N840_0918 ENOG4108K0D peptidase, M48 N840_0920 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) N840_0922 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 N840_0923 ENOG4105BZ1 (ABC) transporter N840_0924 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) N840_0925 ENOG4105T0Z Conserved Protein N840_0928 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups N840_0929 ENOG4107S90 membrAne N840_0930 ENOG4106371 Methyltransferase N840_0932 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) N840_0934 ENOG4105DIT ErfK YbiS YcfS YnhG family protein N840_0935 ENOG4105EAQ (twin-arginine translocation) pathway signal N840_0936 ENOG4105C5X domain protein N840_0937 ENOG4105CGF Aromatic amino acid aminotransferase N840_0938 ENOG4105FCK Membrane N840_0941 ENOG4105CD8 aminopeptidase N N840_0942 ENOG4105E2Y ABC, transporter N840_0943 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component N840_0945 ENOG4105GVF (ABC) transporter N840_0946 ENOG4108UZX fmn reductase N840_0947 ENOG41071VI Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. ElfA is the major fimbrial subunit produced by this operon N840_0948 ENOG4106JJN Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be required for the biogenesis of the ElfA fimbriae N840_0949 ENOG4105CW0 outer membrane usher protein N840_0950 ENOG4108MDY Fimbrial N840_0951 ENOG4105Q7J Fimbrial N840_0952 ENOG4105MX3 Fimbrial N840_0953 ENOG4106PH7 chaperone N840_0956 ENOG4105QVC MOSC domain-containing protein N840_0957 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) N840_0958 ENOG4105C5H ABC transporter N840_0959 ENOG4105F1S paraquat-inducible protein a N840_0960 ENOG4105DY2 Paraquat-inducible protein b N840_0961 ENOG4108Q2G (LipO)protein N840_0962 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) N840_0964 ENOG4105DAN ATP-dependent protease N840_0966 ENOG4105UYK outer membrane protein a N840_0968 ENOG4108RZ1 DNA transformation protein N840_0969 ENOG4105EM2 membrane N840_0970 ENOG410901E Membrane N840_0971 ENOG41088T4 Helicase IV N840_0974 ENOG4105K4P CoA-binding domain protein N840_0977 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 N840_0978 ENOG4108Z0T Part of a sulfur-relay system (By similarity) N840_0979 ENOG4108MN8 Membrane N840_0981 ENOG4105E3S small subunit N840_0982 ENOG4105DPX Hydrogenase, large subunit N840_0983 ENOG4105X7T Ni Fe-hydrogenase, b-type cytochrome subunit N840_0984 ENOG4108USZ hydrogenase N840_0985 ENOG4108VXY Hydrogenase-1 operon protein HyaE N840_0986 ENOG4105MVP hydrogenase-1 operon protein HyaF N840_0987 ENOG4105C4M (Ubiquinol oxidase) subunit I N840_0988 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii N840_0990 ENOG4105D6F Phosphatase N840_0991 ENOG4105D75 Capsular exopolysaccharide family N840_0992 ENOG4107ZF2 Phosphatase N840_0993 ENOG4105DAY polysaccharide export protein N840_0994 ENOG4105E3R (LipO)protein N840_0995 ENOG4108W78 Pfam:DUF1017 N840_0996 ENOG4108Y9B (LipO)protein N840_1000 ENOG41060EU Cold shock-like protein N840_1001 ENOG4105VEQ Cold shock protein N840_1003 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation N840_1004 ENOG4105HEE Binding Domain protein N840_1005 ENOG4105BZU Histidine kinase N840_1006 ENOG4108SV3 Tmao reductase system periplasmic protein tort N840_1007 ENOG4106WF9 DNA-binding transcriptional regulator TorR N840_1008 ENOG4105CUW cytochrome C-TYPE protein N840_1009 ENOG4107QY8 reductase N840_1010 ENOG4108SBI Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity) N840_1014 ENOG4105D6F Phosphatase N840_1015 ENOG4105XH3 N840_1017 ENOG4105XF5 Escherichia coli IMT2125 genomic chromosome, IMT2125 N840_1018 ENOG4105C2W permease N840_1021 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) N840_1025 ENOG4108R86 Transcriptional regulator N840_1026 ENOG4105C26 Dehydrogenase N840_1027 ENOG4105CK7 Sodium proline symporter N840_1029 ENOG410650H (LipO)protein N840_1030 ENOG4105DBE peroxidase N840_1031 ENOG4105D5M phosphate starvation-inducible protein N840_1032 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD N840_1033 ENOG4105CND Glycosyl transferase, family 2 N840_1034 ENOG4107BJW polysaccharide deacetylase N840_1035 ENOG4108TUY outer membrane protein PgaA N840_1036 ENOG4105BZU Histidine kinase N840_1038 ENOG41090WB Transposase is3 is911 N840_1040 ENOG4108T85 Membrane N840_1044 ENOG4107XHZ cytoplasmic chaperone TorD family protein N840_1045 ENOG4108UQ5 membrane protein YcdZ N840_1046 ENOG4105P8Q Curli production assembly transport component CsgG N840_1047 ENOG4108WYR Curli production assembly transport component, CsgF N840_1048 ENOG4108XDW curli assembly protein CsgE N840_1049 ENOG41086KC Transcriptional regulator N840_1050 ENOG4108U0V Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. The minor subunit is the nucleation component of curlin monomers N840_1051 ENOG4105G76 Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin N840_1052 ENOG4105RK8 Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity) N840_1054 ENOG4108UVJ appr-1-p processing domain protein N840_1055 ENOG4107RZC phospholipase d N840_1058 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) N840_1059 ENOG4105NAC (LipO)protein N840_1060 ENOG4108W47 Acidic protein msyB N840_1062 ENOG4105D1S lipid A biosynthesis N840_1064 ENOG4108YYC ycei family N840_1065 ENOG4105DS1 cytochrome b561 N840_1066 ENOG4106974 biofilm formation N840_1068 ENOG4105PVA Biofilm formation regulatory protein BssS N840_1069 ENOG4105MEA DNA damage-inducible protein i N840_1071 ENOG4105F3T (LipO)protein N840_1072 ENOG4105E9S glutaredoxin 2 N840_1074 ENOG4105D9U N-acetyltransferase N840_1076 ENOG4105EP9 oxidoreductase N840_1077 ENOG4105CJR Integral membrane protein (MviN N840_1078 ENOG4105QVD Flagella synthesis protein FlgN N840_1079 ENOG4105M9M anti-sigma28 factor FlgM N840_1080 ENOG4105CKS Flagella basal body P-ring formation protein flgA N840_1081 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) N840_1082 ENOG4108ZC9 flagellar basal-body rod protein flgc N840_1083 ENOG4105W00 Flagellar hook capping protein N840_1084 ENOG4105BZE flagellar hook protein, FlgE N840_1085 ENOG4108KPB Flagellar basal-body rod protein FlgF N840_1086 ENOG4105CGA flagellar basal-body rod protein FlgG N840_1089 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj N840_1090 ENOG4105E1Q flagellar hook-associated protein N840_1091 ENOG4105DTJ flagellar hook-associated protein N840_1092 ENOG4107QQB Ribonuclease E N840_1093 ENOG41071G1 Uncharacterized protein YceQ N840_1094 ENOG4105EI2 Pseudouridine synthase N840_1095 ENOG4108UHJ MAF-like protein N840_1097 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein N840_1101 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase N840_1102 ENOG4105CHR reductase N840_1103 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) N840_1104 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) N840_1105 ENOG4105YAZ 4-amino-4-deoxychorismate lyase N840_1106 ENOG4105HHA aminodeoxychorismate lyase N840_1108 ENOG4107QRG dna polymerase iii N840_1109 ENOG4105F8V Hydrolase, tatD family N840_1110 ENOG4105CI1 PTS System N840_1111 ENOG4105CNM Receptor N840_1112 ENOG4105K59 histidine triad (HIT) protein N840_1113 ENOG41090DQ Lipoprotein N840_1114 ENOG4108WEF Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity) N840_1118 ENOG4105CEP NADH dehydrogenase N840_1119 ENOG4107MBR 17 kDa surface antigen N840_1121 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction N840_1122 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein N840_1123 ENOG4108JA2 transcriptioN-repair coupling factor N840_1124 ENOG4105IQC Inner membrane protein YcfT N840_1125 ENOG4105D60 lipoprotein releasing system transmembrane protein N840_1126 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) N840_1127 ENOG4105D60 lipoprotein releasing system transmembrane protein N840_1129 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) N840_1132 ENOG4107RUE extracellular solute-binding protein family 1 N840_1133 ENOG4105D38 putrescine abc transporter N840_1134 ENOG4105F38 ABC transporter, permease N840_1135 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) N840_1137 ENOG4105EZE Cupin 4 family protein N840_1138 ENOG4105IFJ Histidine kinase N840_1139 ENOG4105XJC Two component transcriptional regulator (Winged helix family N840_1140 ENOG4107QTF adenylosuccinate lyase N840_1144 ENOG4108R99 pseudouridine synthase N840_1145 ENOG4108HMX isocitrate dehydrogenase (NADP) N840_1146 ENOG4106JA9 N840_1147 ENOG4106J3D N840_1148 ENOG4106VW7 Interacts with a short DNA sequence about one-quarter of the way into the major capsid protein gene 23 of T4, and the inhibition occurs when this late gene of the virus is expressed N840_1149 ENOG4108I1J Integrase N840_1150 ENOG4105QYW Excisionase-like protein from lambdoid prophage 14 N840_1152 ENOG4107712 N840_1153 ENOG4105RDA repressor N840_1154 ENOG41078CG DNA-binding transcriptional regulator N840_1155 ENOG4108S1U N840_1162 ENOG4105Y0G tail protein N840_1163 ENOG4105Y9F tail fiber protein N840_1167 ENOG4108C33 Resolvase N840_1168 ENOG4108R4U Hnh endonuclease N840_1171 ENOG41064WM Uncharacterized protein YcgX N840_1172 ENOG4108XDN Transcriptional regulator N840_1173 ENOG4105BZU Histidine kinase N840_1174 ENOG4105WKE Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component N840_1175 ENOG41077SS Probably a connector protein for RcsB C regulation of biofilm formation, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay. Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB N840_1177 ENOG410738I uncharacterized protein ymgC N840_1178 ENOG4105BZU Histidine kinase N840_1181 ENOG410658X N840_1187 ENOG4107QMS site-determining protein N840_1189 ENOG4105S66 prophage protein N840_1190 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium N840_1192 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase N840_1194 ENOG4106PXS Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells N840_1195 ENOG4105KT5 UmuD protein N840_1196 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) N840_1197 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) N840_1200 ENOG4105ED1 spovr family N840_1202 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) N840_1204 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A N840_1206 ENOG4108T7K Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity) N840_1207 ENOG4105Y3U Transglycosylase-associated protein N840_1210 ENOG4105VDH Dihydroxyacetone kinase N840_1211 ENOG4108UTZ Dihydroxyacetone kinase N840_1213 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family N840_1214 ENOG4105I1J Autotransporter N840_1215 ENOG4105C3G gtp-binding protein N840_1217 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria N840_1218 ENOG4105CHH sulfate transporter N840_1219 ENOG4105C5T Phosphoribosyl pyrophosphate synthase N840_1220 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) N840_1222 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) N840_1223 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) N840_1224 ENOG4108YY7 Invasion gene expression up-regulator SirB N840_1225 ENOG41063JG Transcriptional regulator N840_1233 ENOG4105EWV Sodium calcium exchanger membrane region N840_1234 ENOG4105WS7 Cation transport regulator N840_1235 ENOG4108NH8 Cation transport protein N840_1236 ENOG41090EX DsrE family N840_1237 ENOG4105ID0 Putative invasin N840_1238 ENOG4105WH1 Two component transcriptional regulator luxr family N840_1239 ENOG4105BZU Histidine kinase N840_1240 ENOG4105DQQ Major facilitator superfamily MFS_1 N840_1241 ENOG4105CRU nitrate reductase, alpha subunit N840_1242 ENOG4108IUE nitrate reductase beta subunit N840_1243 ENOG4105R3A Nitrate reductase N840_1244 ENOG41076YT nitrate reductase, gamma subunit N840_1249 ENOG4105CIY formyltetrahydrofolate deformylase N840_1251 ENOG4105D78 K07001 NTE family protein N840_1252 ENOG4105I93 response regulator N840_1253 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase N840_1254 ENOG4108SAU DNA-binding protein H-ns N840_1255 ENOG4107104 thymidine kinase N840_1257 ENOG4108EKI Dehydrogenase N840_1258 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein N840_1259 ENOG4108J59 Extracellular solute-binding protein, family 5 N840_1261 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component N840_1262 ENOG4105C3U ABC transporter N840_1263 ENOG4108JQ7 (ABC) transporter N840_1267 ENOG4107SVH Potassium channel protein N840_1268 ENOG4105K9H YciI-like protein N840_1269 ENOG410822N TonB family N840_1270 ENOG4105NAU thioesterase Superfamily protein N840_1273 ENOG4105EIF outer membrane protein W N840_1274 ENOG4108N8X transition metal ion binding N840_1275 ENOG4108Z9Z response to DNA damage stimulus N840_1279 ENOG4105DK0 Indole-3-glycerol phosphate synthase N840_1280 ENOG4108EFP Anthranilate synthase component II N840_1281 ENOG4105CRQ synthase (Component I) N840_1283 ENOG4105DB7 PHP domain protein N840_1284 ENOG4107RTD sua5 ycio yrdc ywlc family protein N840_1285 ENOG4105EG3 transmembrane signal peptide protein N840_1286 ENOG4105FE9 pseudouridine synthase N840_1287 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase N840_1288 ENOG4105UBK short-chain dehydrogenase reductase N840_1289 ENOG4105ERU peptidase N840_1290 ENOG4105RKX Protein of unknown function (DUF2498) N840_1291 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) N840_1292 ENOG4107R11 Transcriptional regulator N840_1295 ENOG4107QM5 aconitate hydratase N840_1297 ENOG4105EYK Phosphatidylglycerophosphatase B N840_1298 ENOG4105Q4A inner membrane protein yciS N840_1299 ENOG4105CFV Tetratricopeptide repeat protein N840_1301 ENOG4108ZJT translation initiation factor, Sui1 N840_1302 ENOG41061RM osmotically inducible lipoprotein N840_1303 ENOG4105N2W Transcriptional regulator N840_1305 ENOG4105BZU Histidine kinase N840_1308 ENOG4105Q4T oxidoreductase N840_1309 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH N840_1310 ENOG4105WDY DNA (cytosine-5-)-methyltransferase N840_1311 ENOG4108JQ2 peptide transport system atp-binding protein N840_1312 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein N840_1313 ENOG4108EU3 peptide transport system, permease N840_1314 ENOG4108I5W peptide transport system, permease protein N840_1315 ENOG4108HIY periplasmic N840_1316 ENOG4105N0E Protein of unknown function (DUF2543) N840_1317 ENOG4105CUB amino acid N840_1318 ENOG4105CFQ glutamine synthetase N840_1319 ENOG4108Z86 Glutamine amidotransferase N840_1320 ENOG4107VRI Transcriptional regulator N840_1321 ENOG4105C26 Dehydrogenase N840_1322 ENOG4105CJP fad dependent oxidoreductase N840_1323 ENOG4108JPW Aminotransferase N840_1324 ENOG4105E51 psp operon transcriptional activator N840_1325 ENOG41087YS Phage shock protein A N840_1326 ENOG4105YYT phage shock protein B N840_1327 ENOG4105FM1 phage shock protein C N840_1328 ENOG4105NNG Peripheral inner membrane phage-shock protein N840_1329 ENOG4105K8Z Phage shock protein N840_1330 ENOG4107QW3 Sucrose phosphorylase N840_1331 ENOG4105WEM extracellular solute-binding protein N840_1332 ENOG4105HS6 binding-protein-dependent transport systems inner membrane Component N840_1333 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component N840_1334 ENOG4107RRD Dehydrogenase N840_1335 ENOG4107TYA transient receptor potential locus N840_1336 ENOG4105CK5 oxidoreductase N840_1337 ENOG4105C71 hydrolase family 65, central catalytic N840_1338 ENOG4107URF beta-phospho-glucomutase N840_1340 ENOG4107EFV Outer membrane protein G N840_1341 ENOG4105FKQ transcriptional regulator N840_1342 ENOG4105CM6 amino acid regulated cytosolic protein N840_1344 ENOG4108JU8 Transcriptional regulator N840_1345 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) N840_1347 ENOG4105KXI murein peptide amidase A N840_1350 ENOG4105ENX hydrolase N840_1351 ENOG4105EQ2 LysR family Transcriptional regulator N840_1352 ENOG4107QSI ABC, transporter N840_1353 ENOG4105D64 Mechanosensitive ion channel N840_1354 ENOG4105F2I Transposase N840_1355 ENOG4105S5I Membrane N840_1356 ENOG4105Q9Y Universal stress protein N840_1357 ENOG4105DS0 Transcriptional regulator, Crp Fnr family N840_1358 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) N840_1359 ENOG4105CFC Transporter N840_1360 ENOG4107RT5 aminobenzoyl-glutamate utilization protein B N840_1361 ENOG4105CH2 amidohydrolase N840_1362 ENOG4106KR7 LysR family Transcriptional regulator N840_1364 ENOG4108DG9 Smr protein MutS2 N840_1365 ENOG4105BZU Histidine kinase N840_1368 ENOG4105C1J atp-dependent rna helicase N840_1370 ENOG4107R08 Integrase N840_1371 ENOG4107160 Rac prophage N840_1372 ENOG41070YT Rac prophage N840_1373 ENOG4106YAH restriction alleviation and modification enhancement N840_1374 ENOG4108PNI recT protein N840_1375 ENOG41076J9 exonuclease VIII N840_1377 ENOG4107C82 Rac prophage N840_1382 ENOG410649Z repressor N840_1383 ENOG4105W7J DNA binding N840_1385 ENOG4105ZTP Protein of unknown function (DUF1376) N840_1386 ENOG4105JBR DNA replication protein N840_1390 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) N840_1391 ENOG4108ES9 ParB domain protein nuclease N840_1396 ENOG4108X9F tail fiber protein N840_1397 ENOG4105UZW Tail fiber assembly protein N840_1398 ENOG4105MN3 Resolvase N840_1399 ENOG4105W3V DNA-binding, transcriptional regulator N840_1401 ENOG4108RW8 Universal stress protein F N840_1402 ENOG4105FCK Membrane N840_1404 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) N840_1406 ENOG41090X5 Heat shock protein hslJ N840_1407 ENOG4105C5I Dehydrogenase N840_1408 ENOG4107H52 Dicarboxylate transport N840_1409 ENOG410689M (LipO)protein N840_1410 ENOG4105WXT Conserved Protein N840_1411 ENOG4108WFR AraC Family Transcriptional Regulator N840_1412 ENOG4105C26 Dehydrogenase N840_1413 ENOG4105F11 amine oxidase N840_1414 ENOG4105DXM phenylacetic acid degradation protein N840_1415 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit N840_1416 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit N840_1417 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit N840_1418 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit N840_1419 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) N840_1420 ENOG4105E39 Enoyl-CoA hydratase N840_1421 ENOG4108UKI Enoyl-CoA hydratase N840_1422 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase N840_1423 ENOG4108ZJI phenylacetic acid degradation protein N840_1424 ENOG4105CHU acetyl-coa acetyltransferase N840_1425 ENOG4105DZS Phenylacetate-CoA ligase N840_1426 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein N840_1427 ENOG4108Z0R Transferase N840_1430 ENOG4108MVM Transposase N840_1431 ENOG4108ZQS transposase N840_1432 ENOG4105F9F transposase N840_1433 ENOG4107S5I aldo keto reductase N840_1435 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase N840_1436 ENOG4108HPI phosphatidate Cytidylyltransferase N840_1437 ENOG4105E8V Alpha Beta Hydrolase Fold protein N840_1438 ENOG41077RS Phosphatase N840_1440 ENOG4105CQ7 ATP-dependent helicase N840_1441 ENOG4107DB1 DUF218 domain N840_1442 ENOG4105C26 Dehydrogenase N840_1444 ENOG4105CPW cytochrome b561 N840_1446 ENOG4105UPP uncharacterized protein ydcA N840_1447 ENOG4107NK6 Hok/gef family N840_1450 ENOG4105C8Q Methyl-accepting chemotaxis N840_1451 ENOG4105DDW LysR family Transcriptional regulator N840_1452 ENOG4105E32 cytoplasmic protein N840_1454 ENOG4105Z2P Protein of unknown function (DUF465) N840_1455 ENOG4108Z9I -acetyltransferase N840_1456 ENOG4107WE3 acetyltransferase YdcK N840_1457 ENOG4108NKP c4-dicarboxylate transporter malic acid transport protein N840_1458 ENOG41088CC tellurite resistance protein tehB N840_1459 ENOG4108KKZ (LipO)protein N840_1461 ENOG4105D7V transposase N840_1462 ENOG4105DKK Benzoate N840_1463 ENOG4108JCI Transcriptional regulator N840_1464 ENOG4105CFP Peptidase U32 N840_1465 ENOG4105RR0 Protein of unknown function (DUF2554) N840_1467 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin N840_1468 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family N840_1469 ENOG4107TYH extracellular solute-binding protein family 1 N840_1470 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) N840_1471 ENOG4105D81 ABC transporter, permease N840_1472 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component N840_1475 ENOG410654E Membrane N840_1476 ENOG4105R71 cytoplasmic protein N840_1477 ENOG4108T9Y Inner membrane protein ydcZ N840_1478 ENOG4108Z7F N-acetyltransferase N840_1479 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein N840_1480 ENOG4108WYP Transcriptional regulator N840_1481 ENOG4105CHB tonB-dependent Receptor N840_1482 ENOG4108NS2 receptor N840_1483 ENOG4105C85 amino acid N840_1484 ENOG4108N27 Glutathione S-transferase N840_1489 ENOG410600T transposase N840_1491 ENOG4108MEJ flavin reductase domain protein N840_1492 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase N840_1493 ENOG4105JAB phenazine biosynthesis protein, phzf family N840_1494 ENOG4105D0D Nitrate reductase 2, gamma subunit N840_1495 ENOG4108NZN Respiratory nitrate reductase 2 delta chain N840_1496 ENOG4108IUE nitrate reductase beta subunit N840_1497 ENOG4105CRU nitrate reductase, alpha subunit N840_1498 ENOG4107QND Nitrite extrusion protein N840_1501 ENOG4105RPH Inner membrane protein YddG N840_1503 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein N840_1504 ENOG4108MG3 formate dehydrogenase N840_1505 ENOG41084S7 Plasmid maintenance system antidote protein N840_1506 ENOG4105DQ4 alcohol dehydrogenase N840_1508 ENOG4107AV5 Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein N840_1509 ENOG4105TPS biofilm-dependent modulation protein N840_1510 ENOG4108Z9K Osmotically inducible protein N840_1511 ENOG4107H6U ABC transporter N840_1512 ENOG4105C3U ABC transporter N840_1513 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component N840_1514 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component N840_1515 ENOG4105DEF Extracellular solute-binding protein, family 5 N840_1516 ENOG4108UQS dipeptidase N840_1517 ENOG4105BZU Histidine kinase N840_1518 ENOG4105BZU Histidine kinase N840_1519 ENOG4105F32 YngK protein N840_1520 ENOG4105E5D amino acid N840_1521 ENOG4105CVK Glutamate decarboxylase N840_1522 ENOG4107RAN Peptidase, M16 N840_1523 ENOG4105PE1 Receptor N840_1524 ENOG4105CQ0 ABC transporter N840_1525 ENOG4105C4X radical SAM domain protein N840_1526 ENOG4105ENH Sulfatase N840_1527 ENOG4105Z68 AraC Family Transcriptional Regulator N840_1529 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit N840_1530 ENOG4106PIH fimbrial-like protein ydeQ N840_1531 ENOG4106318 fimbrial-like protein YdeR N840_1532 ENOG4108WDE Fimbrial protein N840_1535 ENOG4105CAF HipA N-terminal domain protein N840_1536 ENOG41061P8 Persistence to inhibition of murein or DNA biosynthesis regulatory protein N840_1538 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) N840_1539 ENOG4105DKT Transcriptional regulator N840_1540 ENOG4105C2J ABC transporter N840_1541 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane N840_1542 ENOG4105F5R ABC transporter N840_1543 ENOG4105D4B ABC, transporter N840_1544 ENOG41061GT Aldolase N840_1545 ENOG4105K34 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound N840_1547 ENOG4105FFC UPF0187 protein N840_1548 ENOG4107QZW Altronate oxidoreductase N840_1549 ENOG4105BZU Histidine kinase N840_1550 ENOG4105M0C cytoplasmic protein N840_1551 ENOG4105CSV Glutaminase N840_1552 ENOG4105C26 Dehydrogenase N840_1553 ENOG4105EGI Transcriptional regulator N840_1557 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes N840_1558 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF N840_1559 ENOG4106DNR multiple antibiotic resistance protein N840_1560 ENOG4108594 Permease of the drug metabolite transporter N840_1561 ENOG4105E5W Transporter N840_1564 ENOG4105FSR swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria N840_1566 ENOG4108WTK competence damage-inducible protein N840_1567 ENOG4105DGW oligopeptidase A N840_1568 ENOG4105EMU Dehydrogenase N840_1569 ENOG4107XBN GntR Family Transcriptional Regulator N840_1570 ENOG41061EV selenium-binding protein YdfZ N840_1571 ENOG4105DEI Mannitol dehydrogenase N840_1573 ENOG4105W3V DNA-binding, transcriptional regulator N840_1574 ENOG4105MN3 Resolvase N840_1575 ENOG4105UZW Tail fiber assembly protein N840_1576 ENOG410685N tail fiber protein N840_1578 ENOG4106YSC N840_1579 ENOG41064WM Uncharacterized protein YcgX N840_1580 ENOG4106H71 Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation N840_1581 ENOG4106IAW N840_1582 ENOG4105VEQ Cold shock protein N840_1583 ENOG4108YV9 Protein of unknown function (DUF2514) N840_1584 ENOG410762J Rz1-like lipoprotein, Qin prophage N840_1587 ENOG4105QFS Lysis protein S homolog from lambdoid prophage N840_1588 ENOG4105VEQ Cold shock protein N840_1590 ENOG4105HGD Antitermination protein N840_1591 ENOG4108MXB Protein of unknown function (DUF968) N840_1593 ENOG4105WI6 cell killing protein encoded within cryptic prophage N840_1594 ENOG4105K4U addiction module toxin, RelE StbE family N840_1601 ENOG41087BU transcriptional repressor DicA N840_1607 ENOG4106G8A Qin prophage N840_1611 ENOG4105CPQ Dehydrogenase N840_1612 ENOG4105CXK mandelate racemase muconate lactonizing N840_1615 ENOG4108MK9 spermidine N(1)-acetyltransferase N840_1617 ENOG4105KBG Protein of unknown function (DUF1161) N840_1618 ENOG4107QY8 reductase N840_1619 ENOG4105C3J Cysteine desulfurase N840_1620 ENOG4105QAX Iron-sulfur N840_1621 ENOG4107KGK dmso reductase anchor subunit N840_1622 ENOG4108NEM leader-binding protein dmsD N840_1624 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) N840_1625 ENOG4105DAG ROK family N840_1626 ENOG4106NZI LysR family Transcriptional regulator N840_1627 ENOG4105D94 Major Facilitator Superfamily N840_1630 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap N840_1633 ENOG4105DSF transport protein N840_1634 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) N840_1635 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) N840_1636 ENOG4105C5D exported protein N840_1637 ENOG4105D5Q Arginine ornithine antiporter N840_1638 ENOG410642E Short chain dehydrogenase N840_1639 ENOG4105RA2 Membrane N840_1640 ENOG4107EXC regulatoR N840_1641 ENOG4105JJR Histidine kinase N840_1644 ENOG4107GFK fumarate N840_1645 ENOG4105EIP mannose-6-phosphate isomerase N840_1646 ENOG4106J39 exported protein N840_1647 ENOG4108QNI outer membrane porin protein N840_1648 ENOG4105CT4 transporter N840_1649 ENOG4105CNT hydrolase family 2 N840_1650 ENOG4105XEA Tetr family transcriptional regulator N840_1651 ENOG4107ZQV short-chain dehydrogenase reductase N840_1652 ENOG4107P2S Transcriptional regulator N840_1654 ENOG4105C87 Aminotransferase class I and II N840_1656 ENOG4105D9R oxidoreductase N840_1657 ENOG4106C6R beta-lactam resistance protein N840_1658 ENOG4105QZ5 OriC-binding nucleoid-associated protein N840_1659 ENOG4105M9B inner membrane protein ydgK N840_1664 ENOG4108UQQ Electron transport complex N840_1666 ENOG4105CSM endonuclease III N840_1667 ENOG4105DUX Transporter N840_1668 ENOG4108K3A Glutathione S-transferase N840_1669 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) N840_1672 ENOG410642K Lysozyme inhibitor N840_1674 ENOG4108XTF Outer Membrane Lipoprotein N840_1677 ENOG4105Y49 secretion protein, HlyD family N840_1678 ENOG4105DSW Fusaric acid resistance protein N840_1679 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) N840_1680 ENOG4107RGM aldo keto reductase N840_1681 ENOG4105XZD Fe-S protein N840_1682 ENOG4108WUH Transcriptional regulator, TetR family N840_1683 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase N840_1684 ENOG4108UYE Lactoylglutathione lyase N840_1685 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) N840_1686 ENOG4107QRT dEAD DEAH box helicase N840_1687 ENOG4105M2J Glutaredoxin N840_1688 ENOG4105K4H Nlp p60 protein N840_1689 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) N840_1690 ENOG4105F27 Major Facilitator N840_1693 ENOG4105F52 Transcriptional regulator N840_1694 ENOG4105CZQ inner membrane transport protein YdhC N840_1695 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase N840_1696 ENOG4108R6K riboflavin synthase, subunit alpha N840_1701 ENOG4105N0V mono-oxygenase ydhR N840_1702 ENOG4108KTU conserved protein with FAD NAD(P)-binding domain N840_1703 ENOG4108Y7C Conserved Protein N840_1704 ENOG4108NWD Cytochrome N840_1705 ENOG4108393 oxidoreductase Fe-S subunit N840_1706 ENOG4105JVW N840_1707 ENOG4105WE2 aldehyde ferredoxin oxidoreductase N840_1708 ENOG4108PU5 4fe-4S ferredoxin, iron-sulfur binding domain protein N840_1709 ENOG4105RFR Protein of unknown function (DUF2767) N840_1710 ENOG4105CA9 Pyruvate kinase N840_1711 ENOG4105KMX major outer membrane lipoprotein N840_1715 ENOG4105JRK feS assembly protein SufD N840_1716 ENOG4105C3K feS assembly ATPase SufC N840_1718 ENOG4108Z4V iron-sulfur cluster assembly N840_1720 ENOG410671Z uncharacterized protein ydiH N840_1721 ENOG4105KA0 thioesterase Superfamily protein N840_1722 ENOG4105CQB FAD linked oxidase domain protein N840_1723 ENOG4105IPI Membrane N840_1725 ENOG4105SUA Ydil protein N840_1726 ENOG4105EMV Major Facilitator N840_1727 ENOG4105EMV Major Facilitator N840_1730 ENOG4107R0K CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity) N840_1731 ENOG4105C1G acyl-Coa dehydrogenase N840_1732 ENOG4105W4W Transcriptional regulator N840_1733 ENOG4105CV7 Electron transfer flavoprotein N840_1734 ENOG4105C10 Electron transfer flavoprotein N840_1735 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase N840_1736 ENOG41090P5 ferredoxin-like protein N840_1737 ENOG4105CEY Amp-dependent synthetase and ligase N840_1738 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) N840_1740 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) N840_1741 ENOG4106EDX Hemin uptake protein N840_1743 ENOG4108TC0 Diguanylate phosphodiesterase N840_1744 ENOG4108QBX (LipO)protein N840_1746 ENOG4108V06 Glutathione peroxidase N840_1749 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) N840_1752 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) N840_1753 ENOG41082NX 50s ribosomal protein l35 N840_1758 ENOG4108NE3 Salt-induced outer membrane protein N840_1759 ENOG4105DE4 1-phosphofructokinase N840_1760 ENOG4105P10 Uncharacterized protein ydiZ N840_1761 ENOG4105FGM Fructosamine kinase N840_1762 ENOG4107PN8 YfeABCD locus regulator N840_1763 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 N840_1764 ENOG4107K5X Membrane-bound metal-dependent hydrolase N840_1765 ENOG4108ETY sodium dicarboxylate symporter N840_1768 ENOG4105CH6 catalase N840_1770 ENOG4105F8D glycoside hydrolase family 4 N840_1771 ENOG4105EZV Transcriptional regulator N840_1772 ENOG4105VCP PTS System N840_1773 ENOG4105CK1 PTS System N840_1774 ENOG4105VZJ PTS System N840_1775 ENOG4105KKI DNA-binding transcriptional activator OsmE N840_1777 ENOG4105DKD Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity) N840_1779 ENOG4108SPG Periplasmic Protein N840_1783 ENOG4105F4X arginine N840_1785 ENOG4105CGK Exodeoxyribonuclease III N840_1786 ENOG4108RSN SNARE associated Golgi N840_1787 ENOG4108KCW iron-sulfur cluster binding N840_1788 ENOG4108N5C SNARE associated Golgi protein-related protein N840_1789 ENOG4107ZN8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) N840_1790 ENOG4105VNH ABC transporter solute-binding protein N840_1791 ENOG4105CXZ ABC transporter, permease N840_1792 ENOG4108VGW abc transporter atp-binding protein N840_1793 ENOG4107RM6 sulfurtransferase N840_1794 ENOG4108T9J Cdp-alcohol phosphatidyltransferase N840_1795 ENOG4105M6F mutator MutT protein N840_1796 ENOG4105MTM Protein of unknown function (DUF1496) N840_1797 ENOG4105D82 Glutamate dehydrogenase N840_1798 ENOG41065FB inner membrane protein ynji N840_1799 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) N840_1801 ENOG41069NU Nitroreductase N840_1802 ENOG4105D07 Signal peptide peptidase, SppA N840_1803 ENOG4105HDK L-asparaginase N840_1804 ENOG4108RWI nicotinamidase N840_1805 ENOG4108KUU Inner membrane metabolite transport protein ydjE N840_1806 ENOG4105E98 transcriptional regulator DeoR family N840_1807 ENOG4105CPC Aldo Keto reductase N840_1808 ENOG4107UH8 sugar kinase N840_1809 ENOG4105D2N Aldolase N840_1810 ENOG4105CPQ Dehydrogenase N840_1811 ENOG4107TE1 transport protein N840_1812 ENOG4105CPQ Dehydrogenase N840_1813 ENOG4105VUT cytoplasmic protein N840_1815 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase N840_1816 ENOG4105DSB aldose 1-epimerase N840_1817 ENOG4105CV8 reductase N840_1818 ENOG4105GNX MltA-interacting MipA family protein N840_1819 ENOG4105CYN Serine protein kinase N840_1821 ENOG4106KTS Inner membrane protein yeaI N840_1822 ENOG4108KHP Diguanylate cyclase N840_1823 ENOG4108KXH Ybak prolyl-tRNA synthetase associated N840_1827 ENOG4105DJ2 Major Facilitator Superfamily N840_1828 ENOG4105K78 MarR family Transcriptional regulator N840_1829 ENOG4105UCG Domain of unknown function (DUF333) N840_1830 ENOG410620I Diguanylate cyclase N840_1831 ENOG4106G4W N840_1833 ENOG4105Y3U Transglycosylase-associated protein N840_1834 ENOG4105YP6 Domain of unknown function (DUF1869) N840_1835 ENOG4108YS1 cytoplasmic protein N840_1837 ENOG4105EJC lysr family transcriptional regulator N840_1838 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) N840_1839 ENOG4105C94 Transporter N840_1840 ENOG4105DVW rieske (2Fe-2S) N840_1841 ENOG4105E3J oxidoreductase N840_1842 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) N840_1843 ENOG4105CEY Amp-dependent synthetase and ligase N840_1844 ENOG4105Y4Z Outer Membrane Lipoprotein N840_1845 ENOG41072GX Peptidase M22 Glycoprotease N840_1846 ENOG4105DVT helicase N840_1847 ENOG4105M4H endoribonuclease L-psp N840_1848 ENOG4105V2F Uncharacterized protein yoac N840_1850 ENOG4105CRQ synthase (Component I) N840_1852 ENOG4105EJQ L-serine dehydratase N840_1853 ENOG4107XTP (EAL) domain protein N840_1854 ENOG4105EE5 Membrane protein terC N840_1855 ENOG4108EQA pts system N840_1856 ENOG4105ETZ PTS System N840_1857 ENOG4105F3R pts system mannose fructose sorbose family iid N840_1860 ENOG4105DHI Methyltransferase N840_1861 ENOG4105VEQ Cold shock protein N840_1862 ENOG410610J Protein of unknown function (DUF2627) N840_1863 ENOG4105Q3Y exported protein N840_1865 ENOG4105TIK N840_1866 ENOG4105J4Q Transcriptional regulator N840_1867 ENOG4105C0R drug resistance transporter emrb qaca subfamily N840_1869 ENOG4105CN1 protease N840_1871 ENOG4108ZGC gaf domain protein N840_1872 ENOG4105H2K paraquat-inducible protein a N840_1873 ENOG4105DY2 Paraquat-inducible protein b N840_1875 ENOG4105WT8 Protein of unknown function (DUF1480) N840_1876 ENOG4105UVW uncharacterized protein yebW N840_1877 ENOG4108R1E Serine threonine protein phosphatase 1 N840_1880 ENOG4105NKT exported protein N840_1881 ENOG4108PNC copper resistance N840_1882 ENOG4105FXM Copper resistance protein N840_1883 ENOG4105MPK DNA polymerase III subunit theta N840_1884 ENOG4108YGA nitrilase cyanide hydratase and apolipoprotein n-acyltransferase N840_1885 ENOG4105UMD exodeoxyribonuclease X N840_1886 ENOG4105CUG Oligopeptidase b N840_1887 ENOG4108Q2J Inner membrane protein YebE N840_1888 ENOG4105RSZ secreted protein N840_1889 ENOG4105X2V dna damage-inducible protein N840_1891 ENOG4108UHU Aldolase N840_1892 ENOG4105C01 Dihydroxy-acid dehydratase N840_1893 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase N840_1894 ENOG4106KNT transcriptional regulator N840_1895 ENOG4105CA9 Pyruvate kinase N840_1896 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase N840_1897 ENOG4105DR5 peptidase N840_1898 ENOG4105NXV High-affinity zinc uptake system protein N840_1899 ENOG4105FDK ABC transporter N840_1900 ENOG4105FAV ABC, transporter N840_1904 ENOG4107S01 Repressor protein MetJ N840_1906 ENOG4105CDY transcriptional regulatory protein N840_1907 ENOG4108TIT dATP pyrophosphohydrolase N840_1909 ENOG4105D3W isochorismatase N840_1910 ENOG41081XQ Conserved Protein N840_1911 ENOG4105WJG Glutathione N840_1914 ENOG4107QY8 reductase N840_1915 ENOG4105CUW cytochrome C-TYPE protein N840_1917 ENOG4106ZCM YecM protein N840_1920 ENOG4105W13 flagellar protein N840_1921 ENOG4105D7B Flagellar biosynthesis protein flha N840_1922 ENOG4105D00 flagellar biosynthetic protein flhB N840_1923 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) N840_1924 ENOG4108VYJ response regulator receiver protein N840_1925 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) N840_1926 ENOG4105BZU Histidine kinase N840_1927 ENOG4105C8Q Methyl-accepting chemotaxis N840_1928 ENOG4105C8Q Methyl-accepting chemotaxis N840_1929 ENOG4108V3W Chemotaxis protein, CheW N840_1930 ENOG4105CBS Chea signal transduction histidine kinase N840_1931 ENOG4105ER2 Ompa motb domain protein N840_1932 ENOG4107RD7 Flagellar Motor Protein, MotA N840_1933 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region N840_1935 ENOG4108VA4 Universal stress protein N840_1937 ENOG4108K4C ec 3.1.3.12 N840_1938 ENOG4105CNN ABC, transporter N840_1939 ENOG4105C2J ABC transporter N840_1940 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator N840_1941 ENOG4108UEC Ferritin-like protein N840_1942 ENOG4105N4N Protein of unknown function (DUF2766) N840_1944 ENOG4105P23 (LipO)protein N840_1945 ENOG41090A1 ferritin N840_1946 ENOG4105VVZ metal-binding protein N840_1947 ENOG4105E0U tyrosine-specific transport protein N840_1948 ENOG4106RHG Yeca family N840_1952 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase N840_1954 ENOG4105WH1 Two component transcriptional regulator luxr family N840_1955 ENOG4105XVG cytoplasmic protein N840_1956 ENOG4105VJY transcriptional regulator N840_1957 ENOG4105CDA abc transporter atp-binding protein N840_1958 ENOG4105E5Q amino acid AbC transporter N840_1960 ENOG4105EAB amino acid AbC transporter N840_1961 ENOG4108M9K flagella biosynthesis protein FliZ N840_1962 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) N840_1963 ENOG4105I03 Flagellin N840_1964 ENOG4105DTS flagellar hook-associated N840_1965 ENOG4105MQ3 flagellar protein FliS N840_1966 ENOG4105YXP it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity) N840_1967 ENOG4105E5K Alpha-amylase N840_1968 ENOG4108W9D (LipO)protein N840_1969 ENOG41066VF YeeE YedE family protein N840_1970 ENOG4105KSU Redox protein N840_1971 ENOG4108RAV Conserved protein N840_1972 ENOG4108HF7 Gcn5-related n-acetyltransferase N840_1976 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) N840_1977 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) N840_1978 ENOG41090PJ Flagellar assembly protein N840_1979 ENOG4108JIR Flagellum-specific ATP synthase N840_1980 ENOG4105GSA Flagellar export protein flij N840_1981 ENOG4105WF4 Flagellar hook-length control protein N840_1982 ENOG4107ZI8 flagellar basal body-associated protein flil N840_1983 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) N840_1984 ENOG4105DD5 Flagellar motor switch protein N840_1985 ENOG4105K0P flagellar biosynthesis protein N840_1986 ENOG4105CN7 Flagellar biosynthetic protein FliP N840_1987 ENOG4105VS8 Flagellar biosynthetic protein fliq N840_1988 ENOG4105D19 Role in flagellar biosynthesis (By similarity) N840_1989 ENOG4107TKS colanic acid capsular biosynthesis activation protein A N840_1991 ENOG4105YX3 cellular response to acidity N840_1994 ENOG4105BZU Histidine kinase N840_1995 ENOG4105VNZ cytoplasmic protein N840_1996 ENOG4105CKW Inner membrane protein yedI N840_1997 ENOG4105FDR Membrane N840_1998 ENOG41090BB DNA mismatch endonuclease (vsr) N840_1999 ENOG4105DVF Cytosine-specific methyltransferase N840_2000 ENOG4105EST Metal Dependent Phosphohydrolase N840_2001 ENOG4105Y0K Inner membrane protein YedR N840_2005 ENOG4107ZY3 Histidine kinase N840_2006 ENOG4105CK6 Two component transcriptional regulator (Winged helix family N840_2007 ENOG4105VT2 5-hydroxyisourate hydrolase N840_2008 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) N840_2010 ENOG4108MEK Metal-binding protein YodA N840_2011 ENOG4108VKM cytochrome b561 N840_2013 ENOG4105EXZ Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity) N840_2015 ENOG4105TNG K13735 adhesin invasin N840_2017 ENOG4105CSH Transporter N840_2018 ENOG4105FYV Amp nucleosidase N840_2019 ENOG4105CDY transcriptional regulatory protein N840_2021 ENOG4105UQX Mate efflux family protein N840_2023 ENOG4107R11 Transcriptional regulator N840_2024 ENOG4106P55 Transcriptional regulator N840_2026 ENOG4108PXI ErfK YbiS YcfS YnhG N840_2029 ENOG4108YZT Adenosylcobinamide kinase N840_2031 ENOG4105F2I Transposase N840_2035 ENOG4108MVM Transposase N840_2036 ENOG4108ZQS transposase N840_2039 ENOG4105F4K antigen 43 N840_2040 ENOG4108PZQ Inner membrane protein YeeR N840_2041 ENOG4108YGG dna repair protein N840_2042 ENOG4106WJE Protein of unknown function (DUF987) N840_2043 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles N840_2049 ENOG4105DR8 Membrane N840_2050 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) N840_2051 ENOG4105DZ1 carboxypeptidase N840_2052 ENOG4105CJB Exodeoxyribonuclease I N840_2054 ENOG4105CUC YeeE YedE family protein N840_2055 ENOG4105CUB amino acid N840_2057 ENOG4105EQ1 Transcriptional regulator N840_2058 ENOG4108535 NAD dependent epimerase/dehydratase family N840_2059 ENOG4105KRQ Addiction module toxin, Txe YoeB family N840_2060 ENOG4105VTW prevent-host-death family N840_2063 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) N840_2065 ENOG4105ECC imidazole-glycerol-phosphate dehydratase N840_2066 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) N840_2069 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase N840_2070 ENOG4108KPN Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111 M92) and of 17 (in strain K12) N840_2071 ENOG4105C6Y Udp-glucose 6-dehydrogenase N840_2072 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) N840_2074 ENOG4105F2I Transposase N840_2075 ENOG4108TMJ glycosyl transferase N840_2076 ENOG4108UW5 maltose o-acetyltransferase N840_2077 ENOG4105GH9 galactofuranosyltransferase N840_2078 ENOG4107B0W May link the O-antigen tetrasaccharide units into long chains, giving rise to typical smooth LPS N840_2079 ENOG4105D5D udp-galactopyranose mutase N840_2080 ENOG4105ER6 polysaccharide biosynthesis protein N840_2081 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase N840_2082 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) N840_2083 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase N840_2084 ENOG4105C1B dTDP-glucose 4-6-dehydratase N840_2085 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase N840_2086 ENOG4105G1A colanic acid biosynthesis protein N840_2087 ENOG4107T8Q Glycosyl transferase (Group 1 N840_2088 ENOG4105C74 pyruvyl transferase N840_2089 ENOG4105PSV Polysaccharide Biosynthesis Protein N840_2090 ENOG4105D3Q Sugar transferase N840_2091 ENOG4107QKV phosphomannomutase N840_2092 ENOG4105CJT Mannose-1-phosphate guanylyltransferase N840_2093 ENOG4106CD9 glycosyl transferase group 1 N840_2094 ENOG4105FGF GDP-mannose mannosyl hydrolase N840_2095 ENOG4105C30 Nad-dependent epimerase dehydratase N840_2096 ENOG4105C0K Gdp-mannose 4,6-dehydratase N840_2097 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF N840_2098 ENOG4105ECJ Glycosyl Transferase N840_2099 ENOG4108NYJ Colanic acid N840_2100 ENOG4107RXY Glycosyl transferase N840_2101 ENOG41068PY Colanic acid biosynthesis acetyltransferase wcaB N840_2102 ENOG41090RK glycosyl transferase N840_2103 ENOG4105D75 Capsular exopolysaccharide family N840_2104 ENOG4105KJF protein tyrosine phosphatase N840_2105 ENOG4105DAY polysaccharide export protein N840_2106 ENOG4105EE5 Membrane protein terC N840_2107 ENOG4108GAE asmA family N840_2109 ENOG4105DBI uridine monophosphokinase N840_2110 ENOG4105BZU Histidine kinase N840_2111 ENOG4105D03 DNA-3-methyladenine glycosylase II N840_2112 ENOG4105R8A Heat shock protein N840_2113 ENOG4106E1W protein with protein kinase and helix-hairpin-helix DNA-binding N840_2114 ENOG4105ZD5 Uncharacterized protein conserved in bacteria (DUF2314) N840_2115 ENOG4105UM3 Inherit from NOG: serine threonine phosphoprotein phosphatase N840_2116 ENOG4108M24 von Willebrand factor, type A N840_2125 ENOG4105EB3 Histidine kinase N840_2126 ENOG4105E3W Two component transcriptional regulator (Winged helix family N840_2127 ENOG4105KWI UPF0339 protein N840_2128 ENOG4105CFP Peptidase U32 N840_2130 ENOG4105ZTC transcriptional activator, Ogr delta N840_2132 ENOG41076Z6 Uncharacterized protein yegR N840_2135 ENOG41090WB Transposase is3 is911 N840_2137 ENOG4107WTH Galactitol-1-phosphate dehydrogenase N840_2138 ENOG4105DT3 PTS system, galactitol-specific IIc component N840_2139 ENOG41090UW PTS System N840_2140 ENOG41082GB PTS system galactitol-specific transporter subunit IIA N840_2143 ENOG4105EIE fructose-bisphosphate aldolase N840_2144 ENOG4105EAA nucleoside N840_2145 ENOG4108KD5 ADP-ribosylation crystallin J1 N840_2146 ENOG4108TFM Kinase, PfkB family N840_2147 ENOG4105FDP GntR family transcriptional regulator N840_2148 ENOG4108UQ1 hydrolase, family 25 N840_2149 ENOG4105DWF phosphomethylpyrimidine kinase N840_2152 ENOG41061MD high-affinity nickel-transporter N840_2153 ENOG4108Z1S Influences nickel and cobalt homeostasis. May act by modulating RcnA-mediated export of these ions to avoid excess efflux. Not involved in nickel import and does not bind nickel or cobalt ions directly N840_2154 ENOG410662B Type-1 fimbrial protein N840_2155 ENOG4105CW0 outer membrane usher protein N840_2156 ENOG4108MQF Chaperone N840_2157 ENOG41063W2 Fimbrial protein N840_2158 ENOG41067AK Protein of unknown function (DUF2574) N840_2159 ENOG4105D1F ATP-binding protein N840_2164 ENOG4105KKX ATPase associated with various cellular activities aaa_5 N840_2165 ENOG4105RD5 N840_2166 ENOG4105DEG Vwa containing coxe family protein N840_2168 ENOG4108YCW (LipO)protein N840_2169 ENOG4108W15 Protein of unknown function (DUF1456) N840_2170 ENOG4108NEV two component transcriptional regulator, LytTR family N840_2172 ENOG4108XDN Transcriptional regulator N840_2174 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component N840_2175 ENOG4108IJ8 ABC transporter N840_2176 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component N840_2177 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system N840_2178 ENOG4107QK4 glycoside hydrolase, family 3 domain protein N840_2179 ENOG4105CXG d-lactate dehydrogenase N840_2180 ENOG41061WM D-Alanyl-D-Alanine N840_2181 ENOG41069YE inner membrane protein yohC N840_2182 ENOG4105KHU inner membrane protein YohD N840_2183 ENOG4105H9W Short-chain dehydrogenase reductase Sdr N840_2186 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) N840_2188 ENOG41067MG lrgb family N840_2190 ENOG4107GZ4 SanA protein N840_2191 ENOG4105Y9N Membrane N840_2192 ENOG4105BZ8 glutamate synthase N840_2193 ENOG4107SJI Dehydrogenase N840_2194 ENOG4108HWV )-transporter N840_2195 ENOG4105C2J ABC transporter N840_2196 ENOG4105EMA Periplasmic binding protein LacI transcriptional regulator N840_2198 ENOG4105DHF Membrane N840_2200 ENOG4105C4W S-formylglutathione hydrolase N840_2201 ENOG4105D05 Receptor N840_2202 ENOG4108IQI permease N840_2203 ENOG4105DUM transcriptional regulator, lysR family N840_2204 ENOG4105HMI Membrane N840_2205 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) N840_2206 ENOG4105DD7 kinase (PfkB family N840_2207 ENOG4105D9N nucleoside N840_2209 ENOG4108Y4K DNA-binding transcriptional activator N840_2210 ENOG4105D9N nucleoside N840_2211 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) N840_2212 ENOG4105DD7 kinase (PfkB family N840_2213 ENOG4105DM4 PTS System N840_2214 ENOG4105DE4 1-phosphofructokinase N840_2215 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein N840_2216 ENOG4105S8Q sugar efflux transporter N840_2217 ENOG4105KRS Proteinase inhibitor N840_2219 ENOG4105DEI Mannitol dehydrogenase N840_2220 ENOG4105CKI cobalamin synthesis protein N840_2221 ENOG41076MN Phosphoesterase, PA-phosphatase related N840_2222 ENOG4107TT5 NLP P60 protein N840_2223 ENOG4105CXC rtn protein N840_2224 ENOG4105E43 Extracellular solute-binding protein, family 5 N840_2225 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component N840_2226 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component N840_2227 ENOG4108JQ5 ABC transporter N840_2228 ENOG4105HG6 N840_2229 ENOG4105C2C drug resistance transporter, Bcr CflA N840_2230 ENOG4105I08 Pseudouridine synthase N840_2231 ENOG4105CFI type iii restriction protein res subunit N840_2235 ENOG4105E68 Sulfatase N840_2238 ENOG4105F2I Transposase N840_2239 ENOG4105WH1 Two component transcriptional regulator luxr family N840_2240 ENOG4105KWW Biogenesis protein N840_2241 ENOG4107QX9 Thiol disulfide interChange protein N840_2242 ENOG4105DA4 cytochrome c-type biogenesis protein N840_2244 ENOG4105X3C heme exporter protein N840_2245 ENOG41060IM Heme exporter protein N840_2246 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) N840_2247 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) N840_2248 ENOG4105CUW cytochrome C-TYPE protein N840_2249 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) N840_2250 ENOG4105GXZ Ferredoxin-type protein NapH N840_2251 ENOG4108BGM Quinol dehydrogenase periplasmic component N840_2253 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase N840_2254 ENOG4108ZNS ferredoxin-type protein NapF N840_2258 ENOG4105IBP Cyclic peptide transporter N840_2259 ENOG4105CF1 Alkylated DNA repair protein N840_2260 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) N840_2261 ENOG4105CJ2 (LipO)protein N840_2262 ENOG4105FCK Membrane N840_2264 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC N840_2265 ENOG41068CG regulatoR N840_2266 ENOG4105BZU Histidine kinase N840_2267 ENOG4105BZU Histidine kinase N840_2268 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family N840_2269 ENOG4107QP7 CoA-transferase subunit A N840_2270 ENOG4107QNJ CoA-transferase subunit B N840_2271 ENOG4105CRW Short chain fatty acid transporter N840_2272 ENOG4105CHU acetyl-coa acetyltransferase N840_2273 ENOG4105EDV vault protein N840_2274 ENOG41081SK signal peptide protein N840_2276 ENOG4108QJJ Protein of unknown function (DUF1175) N840_2277 ENOG4107FKF Uncharacterized protein conserved in bacteria (DUF2138) N840_2278 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) N840_2280 ENOG4107GHC outer membrane autotransporter N840_2281 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) N840_2282 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) N840_2283 ENOG4105XPH Ferredoxin N840_2284 ENOG4105FQR PH-inducible protein involved in stress response N840_2286 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase N840_2287 ENOG4105CXY transporter N840_2288 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A N840_2290 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) N840_2291 ENOG4105DNE Transposase N840_2294 ENOG4105CSP Major Facilitator Superfamily N840_2296 ENOG4107258 Transcriptional regulator N840_2298 ENOG4108UII YfaZ family N840_2305 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) N840_2307 ENOG4105U65 Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) N840_2308 ENOG4106GZG polymyxin resistance protein B N840_2309 ENOG4105CEY Amp-dependent synthetase and ligase N840_2311 ENOG4108IPT Naphthoate synthase N840_2314 ENOG4105E4F Isochorismate synthase N840_2315 ENOG4105TNS Conserved Protein N840_2316 ENOG4107YB6 acetyltransferase, (GNAT) family N840_2318 ENOG4105Z6G Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is N840_2319 ENOG4105CP2 von willebrand factor, type a N840_2320 ENOG4107VAM peptidase, m28 N840_2321 ENOG4105GDX Domain of unknown function (DUF1877) N840_2322 ENOG4105ZD8 N840_2323 ENOG4106EES N840_2324 ENOG4106HDC N840_2326 ENOG4105C8S subunit m N840_2327 ENOG4105D65 subunit l N840_2328 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) N840_2329 ENOG4107UFS subunit j N840_2330 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) N840_2332 ENOG4107R0R NADH dehydrogenase subunit g N840_2333 ENOG4107QIZ NADH dehydrogenase N840_2334 ENOG4105GKE subunit e N840_2335 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) N840_2338 ENOG4107NQ8 LysR family Transcriptional regulator N840_2339 ENOG4105CHM Aminotransferase N840_2341 ENOG4107QWE )-transporter N840_2342 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 N840_2345 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) N840_2346 ENOG4105C6K Malic enzyme N840_2347 ENOG4105CSX c4-dicarboxylate anaerobic carrier N840_2348 ENOG4105PTV Nudix Hydrolase N840_2349 ENOG4108RE9 Phosphodiesterase N840_2350 ENOG4108SHQ Glutathione S-transferase N840_2351 ENOG4105CYM Glutathione S-transferase N840_2352 ENOG4105KKP D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase N840_2353 ENOG4105ECP epimerase N840_2354 ENOG4105DNE Transposase N840_2355 ENOG4108JEH abc transporter atp-binding protein N840_2356 ENOG4106YG3 ABC transporter N840_2357 ENOG4105DSP amino acid AbC transporter N840_2358 ENOG4105E89 ABC transporter N840_2359 ENOG4105E89 ABC transporter N840_2360 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase N840_2361 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase N840_2362 ENOG4105E96 Colicin v production protein N840_2363 ENOG4108S3P Sporulation domain protein N840_2364 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase N840_2366 ENOG4105DQR SNARE associated Golgi N840_2368 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) N840_2370 ENOG4106WZ1 flagella biosynthesis regulator N840_2371 ENOG4105F9N Major Facilitator Superfamily N840_2372 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) N840_2373 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) N840_2374 ENOG4105MH2 YfcL protein N840_2375 ENOG4108BPE -transporting atpase N840_2376 ENOG4105EJ9 Membrane N840_2379 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) N840_2382 ENOG4105US4 fimbrial-like protein yfcP N840_2383 ENOG4105UGQ Fimbrial N840_2384 ENOG4105NEV Fimbrial N840_2385 ENOG4108FZ9 Chaperone N840_2388 ENOG4108BY2 phosphohistidine phosphatase N840_2391 ENOG4105KZW UPF0381 protein N840_2392 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation N840_2394 ENOG410903C (LipO)protein N840_2395 ENOG4105S64 Formate nitrite transporter N840_2397 ENOG4105DFP Integrase N840_2398 ENOG4105IHM Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity) N840_2399 ENOG4105CKK Glycosyl transferase, family 2 N840_2402 ENOG4105PTU response to oxidative stress N840_2407 ENOG4105H40 N840_2408 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) N840_2409 ENOG4108R7K Metal Dependent Phosphohydrolase N840_2410 ENOG41077V0 CPS-53 (KpLE1) prophage N840_2413 ENOG41065VV Transcription inhibitory protein for the torCAD operon. Also acts as an excisionase and plays an essential role in the defective prophage CPS53 excision N840_2415 ENOG4105W8I Transcriptional regulator N840_2416 ENOG4105C6Z Gluconate N840_2418 ENOG4105C0R drug resistance transporter emrb qaca subfamily N840_2419 ENOG4105CW7 secretion protein, HlyD family N840_2420 ENOG4108WQH regulatoR N840_2422 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F N840_2423 ENOG4108N2Y auxin Efflux N840_2424 ENOG4105CFN oxalyl-CoA decarboxylase N840_2426 ENOG4108V08 YfdX protein N840_2428 ENOG4105W9M Membrane N840_2429 ENOG4105D1S lipid A biosynthesis N840_2431 ENOG4105CHM Aminotransferase N840_2432 ENOG4108HRK Histidine kinase N840_2433 ENOG4105DY9 regulatoR N840_2434 ENOG4108CIP transcriptional regulator N840_2435 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) N840_2436 ENOG4105CN9 Peptidase m42 family protein N840_2437 ENOG4105DC7 peptidase M24 N840_2438 ENOG410863U PTS System N840_2439 ENOG4105R6B The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) N840_2441 ENOG4105VCT ion-transport protein YfeO N840_2442 ENOG4109076 Conserved Protein N840_2444 ENOG4105D9N nucleoside N840_2445 ENOG4108SER Transposase N840_2446 ENOG4108KMM Diguanylate cyclase N840_2449 ENOG4105HZG regulatoR N840_2450 ENOG4105GXM Putative transcription regulator (DUF1323) N840_2456 ENOG4105CN8 Transcriptional regulator N840_2457 ENOG4105EAA nucleoside N840_2458 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) N840_2459 ENOG4108NFH Sugar hydrolase N840_2460 ENOG4108M0I Transcriptional regulator N840_2461 ENOG4105DHU Bile acid N840_2462 ENOG4105VRT cytoplasmic protein N840_2463 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) N840_2466 ENOG4105C6T cysteine synthase N840_2467 ENOG4105KZ7 phosphocarrier protein hpr N840_2468 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) N840_2469 ENOG4105C5Y PTS System N840_2471 ENOG4105M0Y N840_2472 ENOG4105WEC Molybdate metabolism regulator N840_2473 ENOG4105C6T cysteine synthase N840_2474 ENOG4108IJ6 ABC transporter N840_2475 ENOG4105ECW sulfate abc transporter N840_2476 ENOG4108I5D sulfate abc transporter N840_2477 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein N840_2478 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr N840_2481 ENOG4105C5Y PTS System N840_2482 ENOG4107S1E Beta-lactamase N840_2483 ENOG4105EZR dyp-type peroxidase family protein N840_2484 ENOG4105E7K (LipO)protein N840_2485 ENOG4105QZU Inner membrane protein YfeZ N840_2486 ENOG4108R6G acetyltransferase N840_2487 ENOG4108KNB n-acetylmuramoyl-l-alanine amidase N840_2489 ENOG4108K3Z AraC family transcriptional regulator N840_2490 ENOG4108X49 Ethanolamine utilization protein EutK N840_2491 ENOG4106D67 ethanolamine utilization protein N840_2493 ENOG4105CPD ethanolamine ammonia-lyase N840_2494 ENOG4105DFP Integrase N840_2503 ENOG4105DYY Reactivating factor for ethanolamine ammonia lyase N840_2504 ENOG4105ENY Ethanolamine utilization protein eutH N840_2505 ENOG4105C0A alcohol dehydrogenase N840_2506 ENOG4107RWI ethanolamine utilization protein eutJ N840_2507 ENOG4108EKI Dehydrogenase N840_2508 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml N840_2509 ENOG4105KNY Microcompartments protein N840_2510 ENOG4107WUY phosphate acetyltransferase N840_2511 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase N840_2512 ENOG4105NDK ethanolamine utilization protein N840_2513 ENOG4106S4J ethanolamine utilization protein EutP N840_2514 ENOG4108VJN May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place N840_2515 ENOG4105C6K Malic enzyme N840_2516 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) N840_2517 ENOG4105CV1 Transketolase (EC 2.2.1.1) N840_2518 ENOG4108PVD exported protein N840_2519 ENOG4107VIJ nudix hydrolase N840_2520 ENOG4105BZ8 glutamate synthase N840_2521 ENOG4105BZU Histidine kinase N840_2522 ENOG4105BZS acriflavin resistance protein N840_2524 ENOG4105KUZ arsenate reductase N840_2527 ENOG4106KED esterase YpfH N840_2528 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) N840_2529 ENOG4105CGZ zinc metallopeptidase N840_2531 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) N840_2533 ENOG4105RH4 Glycine cleavage system transcriptional repressor N840_2535 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) N840_2536 ENOG4108JPZ Monovalent cation H antiporter subunit D N840_2537 ENOG4107TDF Formate hydrogenlyase subunit 4 N840_2538 ENOG4105D65 subunit l N840_2539 ENOG4107WQX hydrogenase 4 membrane subunit N840_2540 ENOG4108JPZ Monovalent cation H antiporter subunit D N840_2541 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) N840_2543 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit N840_2544 ENOG4105I6X formate hydrogenlyase maturation N840_2545 ENOG4108JUA Transcriptional regulator N840_2547 ENOG4105C02 permease N840_2548 ENOG4105ERG peptidase m48, ste24p N840_2549 ENOG4105K89 arsenate reductase N840_2551 ENOG4105C2W permease N840_2554 ENOG4108V3E phosphoribosylglycinamide formyltransferase N840_2555 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) N840_2556 ENOG4105C9X ppx gppa phosphatase N840_2557 ENOG4105BZU Histidine kinase N840_2558 ENOG41062G3 Protein of unknown function (DUF2633) N840_2559 ENOG4108ZMA Outer membrane lipoprotein N840_2560 ENOG41066DY Membrane N840_2562 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) N840_2564 ENOG4105VPD cellular component movement N840_2566 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) N840_2567 ENOG4105N21 Membrane N840_2573 ENOG4108JQB penicillin-binding protein 1C N840_2574 ENOG4105DN3 alpha-2-macroglobulin domain protein N840_2575 ENOG4105KHC sulfurtransferase N840_2577 ENOG4105YYA enhanced serine sensitivity protein SseB N840_2579 ENOG4105WVQ Fe-S assembly protein IscX N840_2580 ENOG4108ZIT Ferredoxin, 2FE-2S N840_2584 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins N840_2589 ENOG4107XM9 (LipO)protein N840_2590 ENOG4108MN2 Stationary phase inducible protein CsiE N840_2591 ENOG4105D8G Major Facilitator superfamily N840_2592 ENOG4108W5M transcriptional regulator N840_2593 ENOG4108W5M transcriptional regulator N840_2594 ENOG4105FUY alpha subunit N840_2599 ENOG4108SB3 DoxX Family N840_2600 ENOG4108ZKT aldose 1-epimerase N840_2601 ENOG4105CPQ Dehydrogenase N840_2602 ENOG4105CNN ABC, transporter N840_2603 ENOG4108F37 ATP-binding component of a transport system N840_2604 ENOG4105FCA ABC transporter periplasmic-binding protein YphF N840_2605 ENOG4107HQ7 repeat protein N840_2606 ENOG4108NZE NAGC-like transcriptional regulator N840_2608 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) N840_2609 ENOG4108YZA Nitrogen regulatory protein pii N840_2610 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family N840_2611 ENOG4108SKK alpha helix protein N840_2612 ENOG4107WP9 Histidine kinase N840_2614 ENOG4107QIK phosphoribosylformylglycinamidine synthase N840_2616 ENOG4108Z6B deaminase N840_2617 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB N840_2618 ENOG4106G6Q Transcriptional regulator N840_2619 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding N840_2623 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) N840_2627 ENOG4105C3F Signal peptidase i N840_2629 ENOG4105WMJ Positive regulator of sigma E, RseC MucC N840_2630 ENOG4105VQK sigma E regulatory protein, MucB RseB N840_2631 ENOG41069PW sigma-e factor negative regulatory protein N840_2632 ENOG4105EMN RNA polymerase sigma factor N840_2633 ENOG4108IYU L-aspartate oxidase N840_2634 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) N840_2635 ENOG4105C1J atp-dependent rna helicase N840_2636 ENOG41090KR LysR family transcriptional Regulator N840_2640 ENOG4105EIB trna rrna methyltransferase N840_2641 ENOG4105K63 Thioredoxin N840_2642 ENOG4106IUH DTW domain containing protein N840_2643 ENOG4105CD5 CoA-binding domain protein N840_2644 ENOG4105JIM Phosphatidylserine synthase N840_2645 ENOG4105T42 (LipO)protein N840_2646 ENOG4105CSH Transporter N840_2651 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit N840_2653 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase N840_2654 ENOG4105C34 Pseudouridine synthase N840_2655 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane N840_2656 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA N840_2658 ENOG4105CQC Prephenate dehydratase N840_2659 ENOG4105EHE chorismate mutase- prephenate dehydrogenase N840_2660 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) N840_2661 ENOG4105QP9 Protein of unknown function (DUF2799) N840_2662 ENOG4108WS1 N840_2663 ENOG4108KHX Diguanylate cyclase N840_2664 ENOG41090EK ompa motb domain protein N840_2669 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY N840_2670 ENOG4106KVJ cytochrome C assembly protein N840_2671 ENOG4108JU6 CBS domain protein N840_2674 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) N840_2675 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) N840_2676 ENOG4105VDB UPF0125 protein N840_2677 ENOG4108Z1B Cyclase dehydrase N840_2680 ENOG4105DFP Integrase N840_2681 ENOG4106QCB CP4-57 prophage N840_2682 ENOG410679B prophage CP4-57 regulatory protein alpA N840_2683 ENOG4108P8R N840_2684 ENOG4105H5P transposase N840_2685 ENOG4107UNZ domain protein N840_2686 ENOG4105JPW Domain of unknown function (DUF1837) N840_2687 ENOG4107NPW Protein of unknown function (DUF1524) N840_2688 ENOG4106K8T Toxic component of a toxin-antitoxin (TA) module. A stable (half-life 27.6 minutes) endoribonuclease that in the absence of cognate antitoxin RnlB causes generalized RNA degradation. Degrades late enterobacteria phage T4 mRNAs, protecting the host against T4 reproduction. Activity is inhibited by cognate antitoxin RnlB and by enterobacteria phage T4 protein Dmd. Targets cyaA mRNA N840_2689 ENOG4106BHJ Antitoxin component of a toxin-antitoxin (TA) module. A labile antitoxin (half-life of 2.1 minutes) that inhibits the endonuclease activity of cognate toxin RnlA but not that of non- cognate toxin LsoA N840_2690 ENOG4105TS0 gtp-binding protein N840_2691 ENOG4106H6R UPF0380 protein N840_2692 ENOG4108KZE transcriptional regulator N840_2695 ENOG4106J9S Prophage N840_2700 ENOG4105MFG Antirestriction protein N840_2701 ENOG4108XS9 dna repair protein N840_2703 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles N840_2704 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures N840_2706 ENOG4108MGN ATP-binding component of a transport system N840_2712 ENOG4105D5U fad dependent oxidoreductase N840_2713 ENOG4105C26 Dehydrogenase N840_2714 ENOG4108JPW Aminotransferase N840_2715 ENOG4105C85 amino acid N840_2716 ENOG4108PVQ transcriptional regulator N840_2717 ENOG4109066 lysm domain bon superfamily protein N840_2718 ENOG4105VPI YqaE family transport protein N840_2719 ENOG41080HT Transcriptional regulator, arsr family N840_2720 ENOG4108V62 Rhodanese domain protein N840_2721 ENOG4108X73 DNA- binding protein N840_2722 ENOG4108RNS Exports L-alanine (By similarity) N840_2723 ENOG4108WMJ Protein of unknown function (DUF2002) N840_2724 ENOG4108ZQZ Bacterial protein of unknown function (DUF883) N840_2725 ENOG4105WAZ (Glutaredoxin-like protein) NrdH N840_2726 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) N840_2727 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) N840_2728 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) N840_2729 ENOG4108IJ7 Glycine betaine N840_2730 ENOG4108HQS Glycine betaine N840_2731 ENOG4105GIJ Glycine betaine N840_2733 ENOG4108UMN azlc family N840_2734 ENOG4105ZED uncharacterized protein ygaH N840_2735 ENOG4105NTK Transcriptional repressor Mpra N840_2736 ENOG4105CW7 secretion protein, HlyD family N840_2737 ENOG4105C0R drug resistance transporter emrb qaca subfamily N840_2741 ENOG4105W39 Membrane N840_2742 ENOG4107VXZ Hydrolase N840_2748 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) N840_2749 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) N840_2752 ENOG4107TH8 cina domain protein N840_2754 ENOG410787A Pts system, glucitol sorbitol-specific N840_2755 ENOG4105DZY Pts system, glucitol sorbitol-specific N840_2756 ENOG4105VI0 Pts system, glucitol sorbitol-specific N840_2757 ENOG4107QMF Sorbitol-6-phosphate dehydrogenase N840_2758 ENOG4105J92 DNA-binding transcriptional activator GutM N840_2759 ENOG410804X Transcriptional regulator N840_2760 ENOG4105C2X Arabinose 5-phosphate isomerase N840_2762 ENOG4108ESE uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center N840_2764 ENOG4105C8H hydrogenase maturation protein Hypf N840_2765 ENOG4108RC0 Electron transport protein N840_2766 ENOG4105DDV Transcriptional regulator (LacI family N840_2767 ENOG4105C5Y PTS System N840_2768 ENOG4105CS2 ec 3.2.1.21 N840_2769 ENOG4108MG9 hydrogenase 3 maturation protease N840_2770 ENOG4105I6X formate hydrogenlyase maturation N840_2771 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit N840_2772 ENOG4108RG7 formate hydrogenlyase complex iron-sulfur subunit N840_2773 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) N840_2774 ENOG4107TDF Formate hydrogenlyase subunit 4 N840_2775 ENOG4107R30 NADH dehydrogenase N840_2776 ENOG4108MFN small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) N840_2777 ENOG4108VRC Formate hydrogenlyase regulatory protein hycA N840_2778 ENOG410816D Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) N840_2779 ENOG4107RSS Hydrogenase accessory protein HypB N840_2780 ENOG41083WG hydrogenase assembly chaperone N840_2781 ENOG4105CQS hydrogenase expression formation protein HypD N840_2782 ENOG4105C45 hydrogenase expression formation protein (HypE) N840_2783 ENOG4108JUA Transcriptional regulator N840_2784 ENOG4105VXR cytoplasmic protein N840_2786 ENOG4105MEW serine threonine protein phosphatase N840_2787 ENOG4105MVE transcriptional regulator N840_2788 ENOG4105ZXK Dehydrogenase N840_2789 ENOG4105G63 Type III effector Hrp-dependent N840_2790 ENOG4105FB2 class II Aldolase N840_2791 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) N840_2792 ENOG4105C6Z Gluconate N840_2793 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) N840_2794 ENOG4108K5P (LipO)protein N840_2801 ENOG4105N0Z inner membrane protein ygbE N840_2805 ENOG4108MXK alkaline phosphatase isozyme conversion N840_2806 ENOG4105PWE CRISPR-associated protein cas2 N840_2807 ENOG4105TZK CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) N840_2808 ENOG4108Y7V CRISPR-associated protein, Cse3 family N840_2809 ENOG4108VWQ crispr-associated protein N840_2810 ENOG41060M0 Crispr-associated protein, cse4 family N840_2811 ENOG41061HK CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) N840_2812 ENOG4105CYR Crispr-associated protein, cse1 family N840_2813 ENOG4105DTT CRISPR-associated helicase, cas3 N840_2817 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) N840_2818 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase N840_2819 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase N840_2820 ENOG4105WQV ferredoxin-like protein N840_2821 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator N840_2822 ENOG4105YBM electron transfer flavoprotein subunit ygcQ N840_2823 ENOG4106IKH Electron transfer flavoprotein N840_2824 ENOG4105C54 Major Facilitator superfamily N840_2825 ENOG4107R3A FAD linked oxidase domain protein N840_2826 ENOG4105CHR reductase N840_2827 ENOG4108ITV Inner membrane protein yqcE N840_2828 ENOG4108CWB sugar kinase ygcE N840_2829 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) N840_2831 ENOG4105HA9 of methanol dehydrogenase type N840_2834 ENOG4105DXN mazG family N840_2835 ENOG4105MZG transcriptional modulator of maze toxin, mazf N840_2836 ENOG4106A2Z transcriptional regulator antitoxin, MazE N840_2837 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) N840_2838 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) N840_2839 ENOG4105BZU Histidine kinase N840_2840 ENOG4105EQX glucarate dehydratase N840_2841 ENOG4105EQX glucarate dehydratase N840_2842 ENOG4105DJB Major Facilitator Superfamily N840_2843 ENOG4105QDK Flavodoxin N840_2844 ENOG4105DR9 pseudouridine synthase N840_2845 ENOG4105WP7 tRNA pseudouridine synthase C N840_2849 ENOG4105EWT decarboxylase family N840_2850 ENOG4105C44 Serine transporter N840_2851 ENOG4105EJQ L-serine dehydratase N840_2853 ENOG4105C0A alcohol dehydrogenase N840_2854 ENOG4107W7X Aldolase N840_2855 ENOG4105EDR glucose galactose transporter N840_2857 ENOG4105CMG Carbohydrate kinase N840_2859 ENOG4107EDW L-fucose operon activator N840_2861 ENOG4105M08 Membrane N840_2862 ENOG4105ETT transcriptional Regulator, LysR family N840_2864 ENOG4105M5B (LipO)protein N840_2865 ENOG4105C9B Cysteine desulfurase N840_2866 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) N840_2867 ENOG4105CUZ uba thif-type nad fad binding protein N840_2868 ENOG4105CA3 membrane-bound lytic murein transglycosylase N840_2872 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase N840_2873 ENOG4107QZM n-acetylglutamate synthase N840_2874 ENOG4107QYX exodeoxyribonuclease v alpha N840_2875 ENOG4107QKA exodeoxyribonuclease V beta N840_2876 ENOG4107QXK peptidase N840_2877 ENOG4105DSY exodeoxyribonuclease V, gamma N840_2878 ENOG4105RVB Prepilin peptidase dependent protein c N840_2879 ENOG4105SEN Protein of unknown function (DUF2509) N840_2880 ENOG4105JCS prepilin peptidase dependent protein N840_2881 ENOG4105IPU prepilin peptidase dependent protein A N840_2884 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase N840_2887 ENOG4105EE5 Membrane protein terC N840_2888 ENOG4105SUV lipoprotein YgdR N840_2889 ENOG4105CPC Aldo Keto reductase N840_2894 ENOG41060NJ transcriptional regulator N840_2895 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) N840_2896 ENOG4105RQF LysR family Transcriptional regulator N840_2897 ENOG4105CG9 aspartate racemase N840_2898 ENOG4107QNK )-transporter N840_2899 ENOG4105CHR reductase N840_2901 ENOG4105CHU acetyl-coa acetyltransferase N840_2902 ENOG4108MHD transport protein N840_2903 ENOG4105ISV protein with bipartite regulator domain N840_2904 ENOG4108TC1 Transcriptional regulator N840_2905 ENOG4105FV3 N840_2910 ENOG4108YAB Invasion protein N840_2916 ENOG4108MVM Transposase N840_2917 ENOG4108ZQS transposase N840_2920 ENOG4108K5P (LipO)protein N840_2921 ENOG4105C7W Xanthine dehydrogenase N840_2922 ENOG4108HR6 Dehydrogenase N840_2923 ENOG4108UTP (2Fe-2S)-binding domain protein N840_2924 ENOG4108JUB Transcriptional regulator N840_2925 ENOG4105IW6 Carbamoyltransferase N840_2926 ENOG4107RCH Diaminopropionate ammonia-lyase N840_2927 ENOG4107S4Y M20 DapE family protein YgeY N840_2929 ENOG4105C5B carbamate kinase N840_2930 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family N840_2931 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC N840_2932 ENOG4105MFX 4-diphosphocytidyl-2c-methyl-d-erythritol synthase N840_2933 ENOG4105BZ8 glutamate synthase N840_2934 ENOG4107UUR Chlorohydrolase aminohydrolase N840_2935 ENOG410873Y FAD binding domain in molybdopterin dehydrogenase N840_2936 ENOG4105C7W Xanthine dehydrogenase N840_2937 ENOG4105C2W permease N840_2938 ENOG4107QUY Guanine deaminase N840_2939 ENOG4105C7N Xanthine uracil vitamin C permease N840_2940 ENOG4108R8B oxidoreductase Fe-S subunit N840_2941 ENOG4105BZ8 glutamate synthase N840_2942 ENOG4105C2W permease N840_2945 ENOG4105CRK lysyL-tRNA synthetase N840_2947 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) N840_2948 ENOG4105T95 Thiol disulfide interChange protein N840_2949 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) N840_2950 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) N840_2951 ENOG4108YDB Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB N840_2952 ENOG4105Y75 tpr repeat protein N840_2954 ENOG4108UT2 hemolysin iii N840_2955 ENOG4105N5Z UPF0267 protein N840_2956 ENOG4105CS2 ec 3.2.1.21 N840_2957 ENOG4105CYX Short-chain dehydrogenase reductase Sdr N840_2961 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family N840_2962 ENOG4105D0A hydroxylase N840_2963 ENOG4107RAQ aminopeptidase N840_2967 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase N840_2970 ENOG4108JQ1 Dehydrogenase N840_2974 ENOG4105D5P Methylmalonyl-coA mutase N840_2975 ENOG4105DJT lAO AO transport system ATPase N840_2976 ENOG4108M7F enoyl-CoA hydratase isomerase N840_2977 ENOG4105CYC Transferase N840_2978 ENOG4105DEQ transcriptional regulator N840_2979 ENOG4105MPN Membrane N840_2980 ENOG4108ZUB Lysine exporter protein (Lyse ygga) N840_2981 ENOG4105D64 Mechanosensitive ion channel N840_2982 ENOG4105D2N Aldolase N840_2985 ENOG4107Z1W Fructose transport system kinase N840_2986 ENOG4108R4K DNA-binding, transcriptional regulator N840_2987 ENOG4108Q8A Fructose-1,6-bisphosphatase N840_2988 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein N840_2989 ENOG4105CTS PTS system mannitol-specific N840_2990 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia N840_2991 ENOG4105CV1 Transketolase (EC 2.2.1.1) N840_2992 ENOG4108K0D peptidase, M48 N840_2994 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) N840_2998 ENOG4107QNK )-transporter N840_3000 ENOG4105RWS endonuclease I N840_3001 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) N840_3002 ENOG4105D7Z glutathione synthase N840_3005 ENOG4105CZX twitching motility protein N840_3006 ENOG4105DFA alanine racemase domain protein N840_3007 ENOG4108VIA integral membrane protein N840_3009 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) N840_3010 ENOG4105CSA Coproporphyrinogen iii oxidase N840_3011 ENOG4106MH3 alpha helix chain N840_3012 ENOG4105HDK L-asparaginase N840_3013 ENOG4105K33 Periplasmic Protein N840_3014 ENOG41090ED Protein with unknown function (DUF469) N840_3016 ENOG4105CEN a g-specific adenine glycosylase N840_3019 ENOG4105EAA nucleoside N840_3020 ENOG4105CXN decarboxylase N840_3021 ENOG4108UQV Membrane N840_3023 ENOG4105U1E general secretion pathway protein M N840_3026 ENOG410765S (LipO)protein N840_3027 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) N840_3028 ENOG4105F88 accessory colonization factor AcfD N840_3029 ENOG4105DAA L-lactate N840_3030 ENOG4107QP3 malate synthase g N840_3031 ENOG4108ZJF Glcg protein N840_3032 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) N840_3033 ENOG4105EU8 FAD linked oxidase domain protein N840_3034 ENOG4105CQB FAD linked oxidase domain protein N840_3035 ENOG4108KWP DNA-binding transcriptional regulator GlcC N840_3037 ENOG4105F2I Transposase N840_3038 ENOG4108S55 polysaccharide biosynthesis protein N840_3039 ENOG4106FPV ATP-binding protein YghR N840_3040 ENOG4108NDC ATP-binding protein yghS N840_3042 ENOG4105CJ3 phosphate transporter N840_3043 ENOG4106032 Glutathionylspermidine synthase N840_3044 ENOG4105CYM Glutathione S-transferase N840_3045 ENOG41082MF Hydrogenase assembly chaperone hypC hupF N840_3046 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) N840_3047 ENOG4108WGS hydrogenase 2-specific chaperone N840_3048 ENOG4108USZ hydrogenase N840_3049 ENOG4105DPX Hydrogenase, large subunit N840_3050 ENOG4105CJ5 hydrogenase 2 b cytochrome subunit N840_3051 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein N840_3052 ENOG4105E3S small subunit N840_3053 ENOG410900S Protein of unknown function (DUF2623) N840_3055 ENOG4105CPC Aldo Keto reductase N840_3057 ENOG4105CYX Short-chain dehydrogenase reductase Sdr N840_3058 ENOG4108ZZF transport protein (ExbD) N840_3059 ENOG4105CWK Biopolymer transport protein, ExbB N840_3060 ENOG4105C28 cystathionine N840_3061 ENOG4108K81 inner membrane protein YghB N840_3062 ENOG4105CF7 AraC family transcriptional regulator N840_3063 ENOG4108I6A alcohol dehydrogenase N840_3064 ENOG4105CV8 reductase N840_3065 ENOG4105ZKC Conserved Protein N840_3067 ENOG4105CCT upf0313 protein N840_3068 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) N840_3069 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase N840_3070 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) N840_3071 ENOG4108J59 Extracellular solute-binding protein, family 5 N840_3072 ENOG4105WJ3 XRE family Transcriptional regulator N840_3073 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation N840_3074 ENOG4105F4I Transcriptional regulator N840_3075 ENOG4105H4F exported protein N840_3076 ENOG4105XJC Two component transcriptional regulator (Winged helix family N840_3077 ENOG4105DHQ Histidine kinase N840_3078 ENOG4107DEU Inner membrane protein YgiZ N840_3079 ENOG4105NF4 modulator of drug activity N840_3080 ENOG4105VRH Antibiotic biosynthesis monooxygenase N840_3081 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) N840_3082 ENOG4105IPS esterase N840_3083 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) N840_3084 ENOG4108SX3 cytoplasmic protein N840_3085 ENOG41087AY ADP-Ribose pyrophosphatase N840_3087 ENOG4106032 Glutathionylspermidine synthase N840_3088 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b N840_3091 ENOG4105W0Z cytoplasmic protein N840_3092 ENOG4105H8W Fimbrial protein N840_3094 ENOG4108ZQS transposase N840_3095 ENOG4108MVM Transposase N840_3096 ENOG4108TTM chaperone N840_3097 ENOG4108MY7 Fimbrial N840_3099 ENOG4105PV3 Inner membrane protein yqiJ N840_3100 ENOG4107S78 Band 7 protein N840_3107 ENOG4105I7R Adenylate cyclase N840_3108 ENOG4106MWK domain protein N840_3110 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) N840_3111 ENOG4107ZVW dihydroneopterin aldolase N840_3113 ENOG4105EJC lysr family transcriptional regulator N840_3114 ENOG4106DSS Tartrate dehydratase subunit alpha N840_3115 ENOG4107GFK fumarate N840_3116 ENOG4107QPK )-transporter N840_3118 ENOG4105VCC 30S ribosomal protein S21 N840_3119 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) N840_3120 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) N840_3123 ENOG4105Q26 Siderophore-interacting protein N840_3124 ENOG4105NTW Transcriptional regulator N840_3125 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor N840_3127 ENOG4108Y51 tRNA-binding protein N840_3128 ENOG4105CQ4 Transcriptional regulator N840_3129 ENOG4105CNT hydrolase family 2 N840_3130 ENOG4105FK9 beta-D-galactosidase beta subunit N840_3131 ENOG4105E5D amino acid N840_3132 ENOG4107W6W Conserved Protein N840_3133 ENOG4107WCA isomerase N840_3134 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase N840_3135 ENOG4108Z3N Transcriptional regulator N840_3136 ENOG4105R48 this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase N840_3137 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) N840_3138 ENOG4108VKG metal-dependent hydrolase N840_3139 ENOG4108UB4 uncharacterized protein ygjQ N840_3140 ENOG4105EE0 oxidoreductase N840_3141 ENOG4105DU1 integral membrane protein, terc N840_3143 ENOG4105P66 Membrane N840_3144 ENOG4105CTX dehydratase N840_3146 ENOG4105DPW Major facilitator superfamily MFS_1 N840_3147 ENOG4107YCY Transcriptional regulator N840_3148 ENOG4106W5V Membrane N840_3149 ENOG4105IYR Modulates the activity of the EnvZ OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR (By similarity) N840_3150 ENOG4105WAY exported protein N840_3151 ENOG4105NE1 Conserved Protein N840_3152 ENOG41090KG Inner membrane protein YqjE N840_3153 ENOG4105YJD N840_3154 ENOG4108VBZ doxx family N840_3155 ENOG4105CHF Glutathione S-transferase N840_3156 ENOG4105KAF membrAne N840_3157 ENOG4105KAF membrAne N840_3158 ENOG4105CWB LysR family transcriptional Regulator N840_3159 ENOG4108CNN domain protein N840_3160 ENOG4106D80 Uncharacterized protein YhaL N840_3162 ENOG4105C44 Serine transporter N840_3163 ENOG4105EJQ L-serine dehydratase N840_3164 ENOG4105KME endoribonuclease L-psp N840_3165 ENOG4105C6N Formate acetyltransferase N840_3166 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) N840_3168 ENOG4105C7B Threonine dehydratase N840_3169 ENOG410811B TRANSCRIPTIONal N840_3174 ENOG4105BZW Glycerate kinase N840_3175 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase N840_3177 ENOG4105DJB Major Facilitator Superfamily N840_3178 ENOG4105CTX dehydratase N840_3179 ENOG4105ZEG Suppressor protein N840_3180 ENOG4108R8Z these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression N840_3181 ENOG4105E98 transcriptional regulator DeoR family N840_3183 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB N840_3186 ENOG4105E70 isomerase N840_3188 ENOG4108UZY PTS System N840_3189 ENOG4105ETZ PTS System N840_3190 ENOG4105F3R pts system mannose fructose sorbose family iid N840_3191 ENOG4106HBN Galactosamine-6-phosphate isomerase N840_3192 ENOG4105Q10 Fimbrial-like protein N840_3193 ENOG4108VCD Chaperone N840_3194 ENOG4105CW0 outer membrane usher protein N840_3195 ENOG4105I74 Fimbrial protein N840_3196 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) N840_3197 ENOG4105E1C Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity) N840_3199 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) N840_3200 ENOG4105W4M Transport-associated protein N840_3201 ENOG4107S21 permease N840_3202 ENOG4105K4T epimerase N840_3203 ENOG4107R7Y intracellular protease Pfpi family N840_3206 ENOG4108YYD acetyltransferase N840_3207 ENOG4105XPQ lipid carrier protein N840_3208 ENOG4105CFP Peptidase U32 N840_3209 ENOG4106RZ4 Peptidase U32 N840_3210 ENOG4105DEN Luciferase family N840_3211 ENOG4105CIC tryptophan-specific transport protein N840_3212 ENOG4105C1J atp-dependent rna helicase N840_3214 ENOG4105RT1 May be involved in cell division (By similarity) N840_3218 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) N840_3221 ENOG4105CHV Transcription elongation factor NusA N840_3225 ENOG4105DIJ Phosphoethanolamine transferase N840_3229 ENOG4105EEI dihydropteroate synthase N840_3230 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) N840_3231 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) N840_3232 ENOG4105HBR Rna-binding protein N840_3233 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) N840_3235 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control N840_3236 ENOG4105QYV Membrane N840_3239 ENOG4105EAH synthase N840_3240 ENOG4105HVQ Regulatory factor of maltose metabolism N840_3242 ENOG4105VFK BolA family N840_3243 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane N840_3244 ENOG4105E3I toluene tolerance N840_3245 ENOG4107PE3 Mammalian cell entry related domain protein N840_3246 ENOG4105CY3 ABC transporter, permease N840_3247 ENOG4105DHJ ABC, transporter N840_3248 ENOG4105FEU K -dependent Na -Ca exchanger N840_3249 ENOG4105C2X Arabinose 5-phosphate isomerase N840_3250 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase N840_3251 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) N840_3252 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA N840_3253 ENOG4108IUZ ABC transporter N840_3254 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) N840_3255 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA N840_3256 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN N840_3258 ENOG41080Z8 PHOSPHOCARRIER protein N840_3259 ENOG4108NIH transferase activity, transferring phosphorus-containing groups N840_3261 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain N840_3263 ENOG4105BZU Histidine kinase N840_3264 ENOG4105N5T Radical SAM Protein N840_3265 ENOG4105CBC glutamate synthase N840_3266 ENOG4105BZ8 glutamate synthase N840_3267 ENOG4106AJS Involved in induction of the so-called NTR enzymes in response to nitrogen deprivation, as well as in glutamate biosynthesis. May mediate the glutamate-dependent repression of the GLT operon N840_3268 ENOG4108S1B Periplasmic chaperone protein N840_3269 ENOG4105E6S usher protein( N840_3271 ENOG4105F2I Transposase N840_3272 ENOG4105UMR response to DNA damage stimulus N840_3273 ENOG4105DFS Conserved Protein N840_3274 ENOG4108R66 Conserved Protein N840_3280 ENOG4105CEE C4-dicarboxylate transporter N840_3281 ENOG4105KB2 stringent starvation protein b N840_3282 ENOG4107MKT Stringent starvation protein a N840_3283 ENOG4108UJD 30S ribosomal protein S9 N840_3285 ENOG4105D6Z AFG1 family ATPase N840_3286 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III N840_3287 ENOG4105C0H protease N840_3288 ENOG4105C0H protease N840_3291 ENOG4105RID UPF0379 protein yhcN N840_3292 ENOG4105UNR (Barnase) inhibitor N840_3293 ENOG4107Z11 Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity) N840_3296 ENOG4105CR8 Transcriptional regulator N840_3297 ENOG4105D1U peptidase U62 modulator of DNA gyrase N840_3298 ENOG4105QD6 exported protein N840_3299 ENOG4105C03 ribonuclease N840_3300 ENOG4108Z03 MAF-like protein N840_3301 ENOG4105VQ7 Rod shape-determining protein MreD N840_3302 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) N840_3303 ENOG4105DFF Rod shape-determining protein mreb N840_3304 ENOG41062P1 Diguanylate cyclase phosphodiesterase N840_3305 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family N840_3308 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein N840_3309 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase N840_3310 ENOG4105RG0 Membrane N840_3311 ENOG4108IA2 Sodium pantothenate symporter N840_3313 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) N840_3314 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) N840_3315 ENOG4105CEC DNA methylase N-4 N-6 N840_3316 ENOG41061ME transport protein N840_3317 ENOG4108XG4 DNA-binding transcriptional regulator N840_3318 ENOG4105C1P efflux transporter, rnd family, mfp subunit N840_3319 ENOG4105BZS acriflavin resistance protein N840_3320 ENOG4105XCM membrane LIPOPROTEIN N840_3322 ENOG4105EZ7 amino acid ABC transporter N840_3323 ENOG4105DRP amino acid AbC transporter N840_3324 ENOG4105CDA abc transporter atp-binding protein N840_3332 ENOG4108Z0R Transferase N840_3333 ENOG4105SG3 Protein of unknown function (DUF1488) N840_3335 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) N840_3336 ENOG4108WI1 Dna topoisomerase N840_3338 ENOG4105C79 DNA protecting protein DprA N840_3342 ENOG4105C1A potassium transporter peripheral membrane N840_3344 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system N840_3345 ENOG4105W1Y Transcriptional regulator N840_3346 ENOG4105VTS DnaJ-like, subfamily C N840_3348 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) N840_3349 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) N840_3351 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits N840_3352 ENOG41067V7 50S ribosomal protein L36 N840_3353 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) N840_3356 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) N840_3357 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) N840_3359 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) N840_3362 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) N840_3364 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal N840_3366 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) N840_3367 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) N840_3368 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) N840_3369 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) N840_3371 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) N840_3372 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) N840_3375 ENOG4107ACA Calcium-binding protein required for initiation of chromosome replication N840_3376 ENOG410899B May play a regulatory role under conditions of derepressed gsp gene expression N840_3377 ENOG4107KSE General secretion pathway protein C N840_3378 ENOG4105GVR general secretion pathway protein D N840_3379 ENOG4107QHF type ii secretion system protein e N840_3380 ENOG4105D7Q type ii secretion system N840_3381 ENOG4108VAU general secretion pathway protein G N840_3382 ENOG41069X0 general secretion pathway protein h N840_3385 ENOG4105R04 type II secretion system protein K N840_3386 ENOG41063JA Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity) N840_3388 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) N840_3389 ENOG4108UQY Iron-storage protein N840_3390 ENOG4105W53 bacterioferritin-associated ferredoxin N840_3391 ENOG4108NNZ chitinase N840_3399 ENOG4105WWK YheO domain protein N840_3400 ENOG4108V1T peptidylprolyl cis-trans isomerase N840_3402 ENOG4108YZY peptidylprolyl cis-trans isomerase N840_3403 ENOG4105VKU nucleicacid-binding protein N840_3406 ENOG4105C5H ABC transporter N840_3407 ENOG4105DNZ Alpha Beta Hydrolase N840_3409 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) N840_3410 ENOG4108UKZ OsmC family N840_3411 ENOG4107RYR Transcriptional regulator, Crp Fnr family N840_3412 ENOG410613R integral membrane protein, YccS YhfK family N840_3413 ENOG4105C8Y Acetylornithine aminotransferase N840_3414 ENOG4105DDQ anthranilate synthase N840_3415 ENOG4105MZU cell filamentation protein N840_3416 ENOG4106195 uncharacterized protein yhfG N840_3417 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) N840_3419 ENOG4107QZF nitrite reductase NADPH large subunit N840_3420 ENOG4105WZK nitrite reductase NADPH small subunit N840_3421 ENOG4107V9H nitrite transporter N840_3423 ENOG4105VYH N840_3424 ENOG4107QHQ amino acid N840_3425 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine N840_3426 ENOG4107Y0V Not clear, may be involved in an isomerization step N840_3427 ENOG4108KPW sugar kinase N840_3428 ENOG4105FDP GntR family transcriptional regulator N840_3429 ENOG4106PKC pyridoxal phosphate binding N840_3430 ENOG4106M0N transport system permease protein N840_3431 ENOG4105MUZ Protein of unknown function DUF2620 N840_3433 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) N840_3434 ENOG4108626 Racemase N840_3435 ENOG4105RMW regulation of transcription, DNA-dependent N840_3437 ENOG4105C31 Tryptophanyl-tRNA synthetase N840_3438 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) N840_3439 ENOG4105DJV ribulose-phosphate 3-epimerase N840_3440 ENOG4105DFE Dna adenine methylase N840_3441 ENOG4105EGB membrane protein DamX N840_3444 ENOG4105E4G Type IV pilus N840_3445 ENOG4105ITY Required for the use of extracellular DNA as a nutrient N840_3446 ENOG4105XPX DNA utilization protein HofO N840_3447 ENOG41065NF Fimbrial assembly family protein N840_3448 ENOG4108U1Q Pilus assembly protein N840_3449 ENOG4108JQC penicillin-binding protein 1A N840_3450 ENOG4107RK2 ADP-ribose diphosphatase NudE N840_3451 ENOG4105DQY intracellular growth attenuator N840_3452 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 N840_3453 ENOG4105VEJ Heat shock protein N840_3455 ENOG4108MAJ Membrane N840_3457 ENOG4105E0F Histidine kinase N840_3458 ENOG4105DPZ Two component transcriptional regulator (Winged helix family N840_3459 ENOG4108RRZ Transcription elongation factor GreB N840_3460 ENOG4105BZM domain protein N840_3461 ENOG4105XFK Ferrous iron transport protein A N840_3462 ENOG4105CE1 Ferrous iron transport protein b N840_3464 ENOG4105DNE Transposase N840_3466 ENOG4105MJ2 Competence protein N840_3468 ENOG4105C6Z Gluconate N840_3469 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) N840_3470 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) N840_3473 ENOG4105E0Y RtcB Protein N840_3474 ENOG4105CYB regulatoR N840_3475 ENOG4105E98 transcriptional regulator DeoR family N840_3478 ENOG4105C6V Glycerol-3-phosphate dehydrogenase N840_3480 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) N840_3485 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) N840_3486 ENOG41076UM multiple antibiotic resistance (MarC)-related protein N840_3487 ENOG4105C6Z Gluconate N840_3488 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family N840_3489 ENOG4105DIQ Transcriptional regulator N840_3490 ENOG4105C2I pirin domain protein N840_3491 ENOG4105D9R oxidoreductase N840_3493 ENOG4105WCN acetyltransferase N840_3494 ENOG4105GMB type VI secretion system effector, hcp1 family N840_3499 ENOG4106FA4 N840_3500 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) N840_3501 ENOG4105WC8 Conserved Protein N840_3502 ENOG4107T6V glycerophosphoryl diester phosphodiesterase N840_3503 ENOG4108IJ9 (ABC) transporter N840_3504 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component N840_3505 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component N840_3506 ENOG4105BZ7 extracellular solute-binding protein family 1 N840_3507 ENOG4108IV0 ABC, transporter N840_3508 ENOG4105C0Z ABC transporter N840_3509 ENOG4105CF8 branched-chain amino acid ABC transporter, permease N840_3510 ENOG4105C32 Amino acid ABC transporter (Permease) N840_3511 ENOG4105CP9 extracellular ligand-binding receptor N840_3512 ENOG4105U59 -acetyltransferase N840_3514 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) N840_3515 ENOG4105CRP Part of the ABC transporter FtsEX involved in N840_3516 ENOG4105CAK Cell division ATP-binding protein ftsE N840_3517 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) N840_3518 ENOG4106H78 methyltransferase N840_3519 ENOG4105MG3 Membrane N840_3521 ENOG4107FS9 Membrane N840_3522 ENOG4105C59 p-type ATPase N840_3524 ENOG4105EX9 Membrane N840_3525 ENOG4108W1V Lipoprotein N840_3526 ENOG4105F9N Major Facilitator Superfamily N840_3527 ENOG4105DSF transport protein N840_3528 ENOG4107YAK holo-(acyl carrier protein) synthase 2 N840_3529 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein N840_3530 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component N840_3531 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component N840_3532 ENOG4106665 Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) N840_3533 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) N840_3535 ENOG4105CNA YD repeat protein N840_3538 ENOG410600T transposase N840_3539 ENOG4105CMI transporter N840_3540 ENOG4105CJ1 ABC, transporter N840_3541 ENOG4105D0S secretion protein (HlyD N840_3544 ENOG4107UNS conserved inner membrane protein N840_3545 ENOG4105CBX hi0933 family N840_3546 ENOG4105CJ3 phosphate transporter N840_3548 ENOG4108M6U Universal stress protein A N840_3549 ENOG4105DUX Transporter N840_3550 ENOG4105FFN Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity) N840_3551 ENOG4105DGW oligopeptidase A N840_3552 ENOG4105D6S protein involved in catabolism of external DNA N840_3553 ENOG4105DC8 reductase N840_3555 ENOG4105KBH arsR family transcriptional regulator N840_3556 ENOG4107R5R arsenical pump membrane protein N840_3557 ENOG4105K89 arsenate reductase N840_3559 ENOG4105F2I Transposase N840_3560 ENOG4105Y4Z Outer Membrane Lipoprotein N840_3562 ENOG4105KT7 mgtC SapB transporter N840_3563 ENOG4105XXV Acid-resistance protein N840_3564 ENOG41060V2 Acid-resistance protein N840_3565 ENOG4108YK4 Acid-resistance membrane protein N840_3567 ENOG4106WJ0 Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci N840_3568 ENOG4105C1P efflux transporter, rnd family, mfp subunit N840_3569 ENOG4105BZS acriflavin resistance protein N840_3570 ENOG4105D3F AraC Family Transcriptional Regulator N840_3572 ENOG4108NKV transcriptional regulator N840_3573 ENOG4105CVK Glutamate decarboxylase N840_3574 ENOG4105CA0 peroxidase N840_3575 ENOG4105E53 ec 3.2.1.28 N840_3576 ENOG4106S2D Transcriptional regulator N840_3577 ENOG4105CBN LysR family transcriptional regulator N840_3578 ENOG4107H3J ribonuclease N840_3579 ENOG4105CSH Transporter N840_3580 ENOG41066T0 asmA family N840_3581 ENOG4105CMB EAL domain-containing protein N840_3582 ENOG4107SS6 2-dehydro-3-deoxygluconokinase N840_3583 ENOG4105CS0 peptidase N840_3585 ENOG4105BZU Histidine kinase N840_3586 ENOG4105EJG cellulose synthase N840_3587 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) N840_3588 ENOG4107EEX Cellulose synthase regulator protein N840_3589 ENOG4107QZ7 Cellulose synthase catalytic subunit N840_3591 ENOG410661M cytoplasmic protein N840_3592 ENOG4105U74 cellulose biosynthesis protein BcsE N840_3593 ENOG4105WQA Cellulose biosynthesis protein BcsF N840_3594 ENOG4105D1V cellulose synthase operon protein YhjU N840_3597 ENOG4105C44 Serine transporter N840_3598 ENOG4108JQ7 (ABC) transporter N840_3599 ENOG4105C3U ABC transporter N840_3600 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component N840_3601 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component N840_3602 ENOG4105DEF Extracellular solute-binding protein, family 5 N840_3605 ENOG4105FCD Major Facilitator N840_3606 ENOG4105EAX Putative lipase N840_3607 ENOG4108R3E Dna-3-methyladenine glycosylase i N840_3608 ENOG4105HNP -acetyltransferase N840_3609 ENOG4107QY8 reductase N840_3610 ENOG4108ZG0 Ompa motb domain protein N840_3612 ENOG4106JH6 (LipO)protein N840_3613 ENOG4105MVF Transcriptional regulator N840_3614 ENOG4105VEQ Cold shock protein N840_3616 ENOG41060TC Hok gef cell toxic protein N840_3617 ENOG410698F IS150 protein InsA N840_3618 ENOG4105DQ6 Transposase N840_3622 ENOG4105RGS lipoprotein ysaB N840_3623 ENOG4105MEV Acyl-transferase N840_3624 ENOG4108Z12 YiaAB two helix domain-containing protein N840_3625 ENOG410688U Inner membrane protein yiaB N840_3628 ENOG4105DFW ABC transporter N840_3629 ENOG4105C2J ABC transporter N840_3630 ENOG4107RNG ABC transporter N840_3631 ENOG4105T16 Transcriptional regulator (AraC family) N840_3632 ENOG4108UR8 BAX protein N840_3633 ENOG4107T9C Alpha amylase catalytic region N840_3634 ENOG4105JKW Valine--pyruvate aminotransferase N840_3635 ENOG4108XIB electron transport protein ysaA N840_3636 ENOG4105J4Q Transcriptional regulator N840_3638 ENOG4108R66 Conserved Protein N840_3639 ENOG4105XDZ Tripartite ATP-independent periplasmic transporter N840_3640 ENOG4105CG6 trap dicarboxylate transporter dctm subunit N840_3641 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit N840_3642 ENOG4105CMG Carbohydrate kinase N840_3643 ENOG4105H6Q decarboxylase N840_3644 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase N840_3645 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase N840_3648 ENOG4105GNX MltA-interacting MipA family protein N840_3649 ENOG4108Q2M Transcriptional regulator N840_3650 ENOG4105EFX secretion protein, HlyD family N840_3651 ENOG4105KK7 inner membrane protein YiaW N840_3652 ENOG4105C26 Dehydrogenase N840_3653 ENOG4105C0A alcohol dehydrogenase N840_3654 ENOG4105EM7 Selenocysteine-specific translation elongation factor N840_3656 ENOG4108U78 Glutathione S-transferase N840_3657 ENOG4105CNA YD repeat protein N840_3658 ENOG4105NUP lyase containing HEAT-repeat N840_3665 ENOG4105EFX secretion protein, HlyD family N840_3666 ENOG4105FP6 Protein of unknown function (DUF3302) N840_3667 ENOG4105CTS PTS system mannitol-specific N840_3669 ENOG4105E61 Mannitol repressor protein N840_3671 ENOG4108YYI Protein of unknown function (DUF2810) N840_3672 ENOG4105DAA L-lactate N840_3673 ENOG41073TP transcriptional regulator N840_3675 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) N840_3676 ENOG4105D7W serine acetyltransferase N840_3679 ENOG4105VW4 glutaredoxin 3 N840_3680 ENOG4107YZP Rhodanese domain protein N840_3681 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) N840_3682 ENOG41063SB peptidase N840_3683 ENOG4105PXI polysaccharide deacetylase N840_3684 ENOG4105K64 Glycosyl transferase, family 2 N840_3686 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) N840_3687 ENOG4108SEH involved in lipopolysaccharide biosynthesis N840_3689 ENOG4105XA0 heptosyltransferase ii N840_3690 ENOG4105D16 lipopolysaccharide heptosyltransferase i N840_3691 ENOG41068PG O-Antigen polymerase N840_3692 ENOG4108XNZ glycosyl transferase N840_3693 ENOG4108QD8 lipopolysaccharide core biosynthesis protein N840_3694 ENOG4108PDR lipopolysaccharide core biosynthesis protein N840_3695 ENOG4105X1N Glycosyl transferase family 8 N840_3696 ENOG4106AH0 Glycosyl Transferase N840_3697 ENOG4107XU6 Glycosyl transferase (Group 1 N840_3698 ENOG410650X lipopolysaccharide core region biosynthetic process N840_3699 ENOG4107543 (lipo)polysaccharide N840_3700 ENOG4107RJ7 Glycosyl transferase (Group 1 N840_3701 ENOG4105DKP glycosyl transferase, family 9 N840_3702 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase N840_3705 ENOG4105W0E 50S ribosomal protein L33 N840_3708 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase N840_3712 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) N840_3713 ENOG4105DSJ YicC domain protein N840_3714 ENOG4105F5P DNA-damage-inducible protein d N840_3715 ENOG4105EN6 Membrane N840_3717 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) N840_3718 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) N840_3719 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) N840_3720 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase N840_3721 ENOG4105CB5 ATP-dependent DNA helicase recG N840_3722 ENOG4105D6U Sodium Glutamate Symporter N840_3723 ENOG4105C2W permease N840_3724 ENOG4105JV1 AsmA family N840_3725 ENOG4105CJQ hydrolase, family 31 N840_3726 ENOG4105CT4 transporter N840_3729 ENOG4105S8Q sugar efflux transporter N840_3730 ENOG4108UZ3 Transporter N840_3731 ENOG4105D01 (LipO)protein N840_3732 ENOG4105T8A Uncharacterized protein YicS N840_3734 ENOG4108SAJ Protein of unknown function (DUF1198) N840_3735 ENOG4105C7N Xanthine uracil vitamin C permease N840_3737 ENOG4105CXY transporter N840_3738 ENOG4105CXY transporter N840_3739 ENOG4105BZU Histidine kinase N840_3740 ENOG4108KX4 response regulator N840_3741 ENOG4105M71 acetolactate synthase 1 regulatory subunit N840_3742 ENOG4105C7K acetolactate synthase N840_3746 ENOG4105E5M Multidrug resistance protein D N840_3747 ENOG4105J13 transcriptional regulator N840_3748 ENOG4105JP4 Inner membrane protein yidG N840_3749 ENOG4105VG5 Membrane N840_3750 ENOG4106DRA Inner membrane protein YidI N840_3751 ENOG4105CBG Sulfatase N840_3752 ENOG4107RUZ Sss sodium solute transporter superfamily N840_3753 ENOG4108AHD Transcriptional regulator N840_3756 ENOG4105FDP GntR family transcriptional regulator N840_3760 ENOG4105R2A (LipO)protein N840_3761 ENOG4105D99 atp gtp-binding protein N840_3762 ENOG4107WAP fad NAD(P)-binding domain N840_3763 ENOG4105DJB Major Facilitator Superfamily N840_3765 ENOG4108RTU Aldolase N840_3766 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 N840_3767 ENOG4105EMF GntR family transcriptional regulator N840_3768 ENOG410657R replicase EC 2.7 N840_3769 ENOG410667J hydrolase N840_3770 ENOG4105VP5 Bacterial protein of unknown function (DUF937) N840_3771 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) N840_3773 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) N840_3782 ENOG4108P6C Tryptophan transporter of low affinity N840_3785 ENOG4105E8Q phosphopantetheinyl transferase N840_3786 ENOG4108YYH Nadph-dependent fmn reductase N840_3787 ENOG4105C7N Xanthine uracil vitamin C permease N840_3789 ENOG4106HGK Inner membrane protein yieI N840_3790 ENOG4106611 bacteriocin immunity N840_3791 ENOG4107VKM 6-phosphogluconolactonase N840_3792 ENOG4105DYC esterase N840_3793 ENOG4108P68 Outer membrane porin N840_3794 ENOG4105CS2 ec 3.2.1.21 N840_3795 ENOG4105C5Y PTS System N840_3796 ENOG4105CID antiterminator N840_3797 ENOG4108UTW Plays a role in the regulation of phosphate uptake N840_3798 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) N840_3799 ENOG4105E2Z phosphate ABC transporter (Permease N840_3800 ENOG4105C8U phosphate abc transporter N840_3801 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) N840_3802 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) N840_3810 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) N840_3812 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation N840_3815 ENOG4105QTB Flavodoxin N840_3816 ENOG4108VVK transcriptional Regulator, AsnC N840_3818 ENOG4105EV2 VWA domain protein interacting with AAA ATPase N840_3821 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) N840_3822 ENOG4105C2J ABC transporter N840_3823 ENOG4105CNN ABC, transporter N840_3824 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator N840_3825 ENOG4108RVA ribokinase N840_3826 ENOG4105ETE Transcriptional regulator (LacI family N840_3827 ENOG4105C0R drug resistance transporter emrb qaca subfamily N840_3828 ENOG4107EJG GntR family transcriptional regulator N840_3836 ENOG4108WFC UPF0438 protein yifE N840_3837 ENOG4105C0P Mg chelatase subunit ChlI N840_3841 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit N840_3842 ENOG4105CM2 brancheD-chain amino acid aminotransferase N840_3844 ENOG4105C7B Threonine dehydratase N840_3845 ENOG4105EMY transcriptional regulator N840_3847 ENOG4105KQ5 peptidylprolyl cis-trans isomerase N840_3849 ENOG4105C4R Atp-dependent dna helicase N840_3850 ENOG4105C9X ppx gppa phosphatase N840_3852 ENOG4105K63 Thioredoxin N840_3854 ENOG4105ESV Glycosyl transferase, family 4 N840_3856 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase N840_3857 ENOG4108IJ1 Dehydrogenase N840_3858 ENOG4105C1B dTDP-glucose 4-6-dehydratase N840_3859 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) N840_3860 ENOG4108WJ1 acetyltransferase N840_3861 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase N840_3862 ENOG4105EGZ biosynthesis protein N840_3871 ENOG4105C4X radical SAM domain protein N840_3872 ENOG4105ENH Sulfatase N840_3874 ENOG410601J HemY protein N840_3875 ENOG4105ECF c-methyltransferase N840_3876 ENOG41076E6 Uroporphyrinogen-III Synthase N840_3878 ENOG4107T0K Adenylate cyclase N840_3880 ENOG4105S7Z (LipO)protein N840_3882 ENOG4105CT0 Protein of unknown function, DUF484 N840_3884 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant N840_3885 ENOG4105C4R Atp-dependent dna helicase N840_3886 ENOG4108T58 Mg2 transport protein CorA N840_3887 ENOG4107QUT magnesium and cobalt transport protein CorA N840_3888 ENOG4105NRM Membrane N840_3889 ENOG4106WR8 Inner membrane protein YigG N840_3890 ENOG4105FR1 rard protein N840_3891 ENOG4108VUY thioesterase Superfamily protein N840_3892 ENOG4105HDD phospholipase N840_3893 ENOG4105C9U ATP-dependent DNA helicase RecQ N840_3896 ENOG4108EUD Lysophospholipase N840_3897 ENOG4105DQF Hydrolase N840_3898 ENOG4105EMK carboxylate amino acid amine transporter N840_3899 ENOG4105DZ2 Transcriptional regulator N840_3900 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) N840_3901 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) N840_3902 ENOG4108I5U Uridine phosphorylase N840_3903 ENOG4105CGY Dna recombination protein N840_3905 ENOG4105JC1 sterol-binding domain protein N840_3906 ENOG4105JC1 sterol-binding domain protein N840_3908 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) N840_3909 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) N840_3910 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) N840_3911 ENOG4105F8V Hydrolase, tatD family N840_3912 ENOG4105MDZ Transcriptional activator rfaH N840_3913 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) N840_3914 ENOG4107QK7 reductase N840_3915 ENOG4105CHU acetyl-coa acetyltransferase N840_3918 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein N840_3919 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) N840_3920 ENOG4108RR8 protoporphyrinogen oxidase N840_3926 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b N840_3927 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) N840_3928 ENOG4105PC1 Conserved Protein N840_3929 ENOG4105E27 serine threonine protein kinase N840_3930 ENOG4108Z33 Thiol disulfide Interchange Protein N840_3932 ENOG4106HNH Acyl-transferase N840_3933 ENOG4105C2M dna polymerase I N840_3938 ENOG4105D4P Coproporphyrinogen iii oxidase N840_3939 ENOG4106FIY N840_3940 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family N840_3941 ENOG4105CUX Signal transduction histidine kinase N840_3942 ENOG4105C5F glutamine synthetase N840_3944 ENOG4108K85 Transcriptional regulator N840_3945 ENOG4108KHF Resistance protein N840_3946 ENOG4105R9B Major Facilitator N840_3947 ENOG4108KUC Outer membrane channel protein that allows an efficient diffusion of low-molecular-weight solutes such as small sugars and tetraglycine. However, the specific substrate recognized by the OmpL channel is N840_3948 ENOG4105CT4 transporter N840_3949 ENOG4105CT4 transporter N840_3950 ENOG4105CJQ hydrolase, family 31 N840_3951 ENOG4107WI4 Aldose-1-epimerase N840_3952 ENOG4107QKS N-acylglucosamine 2-epimerase N840_3953 ENOG4105D2M Aldolase N840_3954 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase N840_3955 ENOG4108MGF sugar kinase N840_3956 ENOG4105E98 transcriptional regulator DeoR family N840_3957 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 N840_3960 ENOG4105SUU thioesterase domain N840_3961 ENOG4106UEE Transcriptional regulator N840_3962 ENOG41068KX affects formate dehydrogenase-N N840_3964 ENOG4108MG3 formate dehydrogenase N840_3965 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein N840_3968 ENOG4108V87 frv operon regulatory protein N840_3969 ENOG4106C3V frv operon regulatory protein N840_3970 ENOG4105CN9 Peptidase m42 family protein N840_3971 ENOG4105DM4 PTS System N840_3972 ENOG41064BA PTS system, fructose-specific, IIA component N840_3980 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) N840_3982 ENOG4108RPX mosc domain containing protein N840_3983 ENOG4105E0F Histidine kinase N840_3984 ENOG4105E3W Two component transcriptional regulator (Winged helix family N840_3985 ENOG4105FMW periplasmic N840_3988 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein N840_3991 ENOG4105EBK exported protein N840_3992 ENOG4108VTS Membrane N840_3993 ENOG41065TG regulatoR N840_3995 ENOG4105DP0 ferredoxin-NADP reductase N840_3996 ENOG4105CBT Fructose-1,6-bisphosphatase N840_3998 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) N840_4001 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase N840_4002 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) N840_4004 ENOG41063M6 Cell Division Protein N840_4005 ENOG4105ETE Transcriptional regulator (LacI family N840_4006 ENOG4105C25 Primosomal protein n' N840_4008 ENOG4107S01 Repressor protein MetJ N840_4010 ENOG4105C28 cystathionine N840_4011 ENOG4105CFH Aspartokinase N840_4012 ENOG4105SYT Methylenetetrahydrofolate reductase N840_4013 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) N840_4014 ENOG4108Q5Y Membrane N840_4015 ENOG4108XC3 NADH ubiquinone oxidoreductase N840_4016 ENOG4105DCT glycerol dehydrogenase N840_4017 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) N840_4018 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) N840_4019 ENOG4105DM4 PTS System N840_4020 ENOG4108YRF PTS System N840_4021 ENOG4105C6N Formate acetyltransferase N840_4022 ENOG4108AHH pyruvate formate lyase II activase N840_4023 ENOG4108XCZ PTS System N840_4024 ENOG4106R3P AraC family transcriptional regulator N840_4025 ENOG4105DIJ Phosphoethanolamine transferase N840_4028 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase N840_4029 ENOG4105CAS nag kinase N840_4032 ENOG4105C5Q Transcriptional regulator N840_4035 ENOG4108Y73 Membrane N840_4037 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) N840_4043 ENOG4105D4A Cell wall formation (By similarity) N840_4044 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase N840_4051 ENOG4105PM1 preprotein translocase subunit SecE N840_4052 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) N840_4059 ENOG410645W Thiamin biosynthesis protein ThiH N840_4061 ENOG4105D41 biosynthesis protein thiH N840_4063 ENOG4105WHD thiamine biosynthesis protein ThiS N840_4064 ENOG4105D06 uba thif-type nad fad binding protein N840_4071 ENOG4105R2J Conserved Protein N840_4072 ENOG4105K70 DNA-binding protein N840_4073 ENOG4108T8B Protein of unknown function (DUF1481) N840_4074 ENOG4105JBU Binds zinc. Could be an important component of the zinc- balancing mechanism N840_4075 ENOG4105BZU Histidine kinase N840_4076 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family N840_4077 ENOG4105C12 Phosphoribosylglycinamide synthetase N840_4083 ENOG41062WK cellular response to acidity N840_4084 ENOG4105K5X acetyltransferase N840_4086 ENOG4107QP3 malate synthase g N840_4087 ENOG4108I9X Isocitrate lyase N840_4090 ENOG41069M3 Transcriptional regulator N840_4091 ENOG4105C3R Methionine synthase N840_4092 ENOG4105EAM Na Pi-cotransporter N840_4094 ENOG4105FE9 pseudouridine synthase N840_4095 ENOG4108ZR5 Conserved Protein N840_4096 ENOG4105CFH Aspartokinase N840_4099 ENOG4108MDC (LipO)protein N840_4100 ENOG4108Q9C Periplasmic Protein N840_4101 ENOG4105E3R (LipO)protein N840_4104 ENOG4107QNK )-transporter N840_4105 ENOG4105EG2 ABC transporter, permease N840_4106 ENOG4105D56 permease protein N840_4107 ENOG4107FKK extracellular solute-binding protein family 1 N840_4108 ENOG4108IJ9 (ABC) transporter N840_4110 ENOG4107W52 maltose operon periplasmic protein N840_4115 ENOG41080IJ Diacylglycerol kinase N840_4117 ENOG4107R73 Mate efflux family protein N840_4118 ENOG4105VDW Csbd family N840_4119 ENOG4105MYN Zinc uptake regulation protein N840_4122 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) N840_4123 ENOG4105P4Z Phage shock protein G N840_4124 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein N840_4125 ENOG4105CDU Replicative dna helicase N840_4126 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) N840_4127 ENOG4105CGF Aromatic amino acid aminotransferase N840_4129 ENOG4105F0S class B acid phosphatase N840_4130 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme N840_4131 ENOG4105MSB protein, conserved in bacteria N840_4132 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) N840_4133 ENOG4108UUM single-stranded DNA-binding protein N840_4134 ENOG4105PMV Membrane N840_4135 ENOG4108M8H domain protein N840_4136 ENOG4108W3Q Transcriptional regulator N840_4137 ENOG4108Z4X TRANSCRIPTIONal N840_4139 ENOG4105C7N Xanthine uracil vitamin C permease N840_4140 ENOG4105EEQ Na H antiporter N840_4143 ENOG41062QD Membrane N840_4144 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) N840_4146 ENOG4105JJ8 Cytochrome c nitrite reductase, pentaheme subunit N840_4147 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein N840_4148 ENOG4105DVI reductase, NrfD N840_4149 ENOG4108QKW cytochrome c-type biogenesis protein N840_4151 ENOG4108W0S formate-dependent nitrite reductase complex N840_4152 ENOG4105CK2 sodium dicarboxylate symporter N840_4153 ENOG41082ND Uncharacterized protein yjcO N840_4155 ENOG4105ETP RND efflux system, outer membrane lipoprotein N840_4156 ENOG4108MI0 Resistance protein N840_4157 ENOG4105J12 Multidrug resistance protein mdtN N840_4158 ENOG4106833 N840_4159 ENOG4105EUZ Beta-lactamase domain protein N840_4160 ENOG4107TFG D-allose kinase N840_4161 ENOG4105UP7 3-epimerase N840_4162 ENOG4105CNN ABC, transporter N840_4163 ENOG4105C2J ABC transporter N840_4164 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator N840_4165 ENOG4105NYY transcriptional regulator, RpiR N840_4166 ENOG4108YZG isomerase N840_4167 ENOG4106ZVZ Escherichia coli IMT2125 genomic chromosome, IMT2125 N840_4168 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein N840_4169 ENOG410849A acetyltransferase, (GNAT) family N840_4170 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) N840_4171 ENOG4105FD8 phosphonate metabolism protein PhnM N840_4172 ENOG4105HRV phosphonate c-p lyase system protein phnl N840_4173 ENOG4105ENV phosphonate C-P lyase system protein PhnK N840_4174 ENOG4105FT8 Phosphonate metabolism N840_4175 ENOG4105EKV Phosphonate metabolism protein N840_4176 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH N840_4177 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG N840_4178 ENOG4107RJJ Transcriptional regulator N840_4180 ENOG4105EHI Phosphonate ABC transporter, periplasmic N840_4181 ENOG4105D5T phosphonate abc transporter N840_4182 ENOG4108SQ4 Glyoxalase Bleomycin resistance protein (Dioxygenase N840_4183 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA N840_4184 ENOG4108F5E vimentin N840_4185 ENOG4108YIV N840_4186 ENOG4105CSH Transporter N840_4188 ENOG4105ECM Sensor protein basS pmrB N840_4189 ENOG4105XJC Two component transcriptional regulator (Winged helix family N840_4190 ENOG4105DIJ Phosphoethanolamine transferase N840_4191 ENOG4105D5Q Arginine ornithine antiporter N840_4192 ENOG4106ZGR Transcriptional regulator N840_4193 ENOG4105CXN decarboxylase N840_4194 ENOG4108K2B transcriptional regulator N840_4195 ENOG4105F8D glycoside hydrolase family 4 N840_4196 ENOG4105CT4 transporter N840_4197 ENOG4108R5S membrane N840_4198 ENOG4107GFK fumarate N840_4199 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter N840_4200 ENOG4108MRH transcriptional regulatory protein N840_4201 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism N840_4202 ENOG4105VR1 Pfam:DUF1271 N840_4203 ENOG410830R acetyltransferase N840_4206 ENOG4105CRK lysyL-tRNA synthetase N840_4207 ENOG4105DUX Transporter N840_4208 ENOG4105CXN decarboxylase N840_4209 ENOG4105D5Q Arginine ornithine antiporter N840_4210 ENOG4108M3R transcriptional activator CadC N840_4213 ENOG4108SIC Transcriptional regulator N840_4214 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) N840_4216 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter N840_4217 ENOG4108IJ0 Aspartate ammonia-lyase N840_4218 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 N840_4219 ENOG4105DVH amino acid N840_4222 ENOG4108ZVF (LipO)protein N840_4223 ENOG4105MTB Uncharacterized protein YjeJ N840_4224 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein N840_4226 ENOG4106HKS Entericidin EcnA/B family N840_4227 ENOG4106BSU Entericidin B N840_4228 ENOG4105KPY Small multidrug resistance protein N840_4229 ENOG4105QNF Outer membrane lipoprotein N840_4230 ENOG41066YJ Beta-lactamase N840_4233 ENOG4105E33 succinate dehydrogenase N840_4234 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) N840_4236 ENOG4107SC7 Inner membrane transporter yjeM N840_4237 ENOG4106V5W N840_4238 ENOG4106CG8 Inner membrane protein YjeO N840_4239 ENOG4105EGS Mechanosensitive ion channel N840_4247 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) N840_4248 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) N840_4249 ENOG4105K8N protein family UPF0079, ATPase N840_4250 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase N840_4253 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) N840_4254 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) N840_4255 ENOG4107QJR hflk protein N840_4256 ENOG4105EPW hflc protein N840_4260 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) N840_4261 ENOG4105C2N RNA methyltransferase TrmH family group 3 N840_4262 ENOG4105FUX Conserved Protein N840_4263 ENOG4108P9J Phage shock protein A N840_4264 ENOG4107VNS Protein of unknown function (DUF2491) N840_4265 ENOG4105Z6B inner membrane protein yjfl N840_4266 ENOG4108KXT Conserved Protein N840_4267 ENOG4106032 Glutathionylspermidine synthase N840_4268 ENOG4105CSU acyl-Coa dehydrogenase N840_4269 ENOG4105S17 UPF0379 protein yjfN N840_4270 ENOG4105WSB biofilm stress and motility protein A N840_4271 ENOG4108MXZ Esterase N840_4274 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC N840_4275 ENOG410907W The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in ascorbate transport N840_4276 ENOG4106ETB IIa component N840_4283 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) N840_4287 ENOG4105FHY Opacity-associated protein A N840_4288 ENOG4108V1T peptidylprolyl cis-trans isomerase N840_4289 ENOG4105C85 amino acid N840_4291 ENOG4105DXC membrane N840_4292 ENOG4105ECR NmrA family N840_4293 ENOG4105KVH Transcriptional regulator N840_4294 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic N840_4295 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase N840_4297 ENOG4108UUE Transcriptional regulator N840_4298 ENOG41061GZ Protein of unknown function (DUF1107) N840_4299 ENOG4105C37 (CBS) domain N840_4301 ENOG4105CFU surface antigen N840_4303 ENOG4108ZHD aig2 family N840_4304 ENOG41087RY SpoVT_AbrB N840_4305 ENOG4105MZG transcriptional modulator of maze toxin, mazf N840_4306 ENOG4105F0N pyrophosphate phospho-hydrolase N840_4307 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator N840_4308 ENOG4105C2J ABC transporter N840_4309 ENOG4107R9N ABC transporter N840_4310 ENOG41062B0 ABC transporter, permease N840_4312 ENOG4105DFU Cell wall formation (By similarity) N840_4314 ENOG4105CMS peptidase U62, modulator of DNA gyrase N840_4316 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) N840_4317 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase N840_4318 ENOG4105CG3 alpha amylase, catalytic region N840_4319 ENOG4105C5Y PTS System N840_4320 ENOG4105D4X repressor N840_4322 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic N840_4323 ENOG4105KME endoribonuclease L-psp N840_4326 ENOG41077AM PyrBI operon attenuator N840_4327 ENOG4108UQ8 endoribonuclease L-psp N840_4328 ENOG4105F6U Short-chain dehydrogenase reductase Sdr N840_4330 ENOG4105XEP YhcH YjgK YiaL family protein N840_4332 ENOG4105DBV ornithine carbamoyltransferase N840_4333 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) N840_4334 ENOG4108MJ3 acetyltransferase N840_4335 ENOG4108M3P Membrane N840_4336 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) N840_4337 ENOG4105MYG DNA polymerase iii, chi subunit N840_4339 ENOG4108M8S permease YjgP YjgQ family protein N840_4340 ENOG4108K5H permease YjgP YjgQ family protein N840_4341 ENOG4105D7A ATP-binding protein N840_4342 ENOG4105K2J Transcriptional regulator N840_4343 ENOG4105C6Z Gluconate N840_4344 ENOG4105CHR reductase N840_4345 ENOG4105CPQ Dehydrogenase N840_4346 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family N840_4347 ENOG4105DQ4 alcohol dehydrogenase N840_4350 ENOG4108ZQS transposase N840_4351 ENOG4108MVM Transposase N840_4354 ENOG4105VNT transposase (IS4 family) protein N840_4355 ENOG4105JHE Major Facilitator Superfamily N840_4356 ENOG4107RJ5 oxidoreductase N840_4361 ENOG4105F9F transposase N840_4365 ENOG4108IHU transport system permease protein N840_4366 ENOG4105DQ5 transport system permease protein N840_4367 ENOG4108HUF Transporter N840_4368 ENOG4105GAV receptor N840_4369 ENOG4108S3W Anti-feci sigma factor, fecr N840_4370 ENOG4108SF5 RNA Polymerase N840_4373 ENOG4105DKT Transcriptional regulator N840_4374 ENOG4105C6Z Gluconate N840_4375 ENOG4105C01 Dihydroxy-acid dehydratase N840_4376 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) N840_4377 ENOG4106P37 HTH-type transcriptional regulator YjhI N840_4378 ENOG4108PQ7 sgc region transcriptional regulator N840_4379 ENOG4108RK0 3-epimerase N840_4380 ENOG4108XBJ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) N840_4382 ENOG4106P19 photosystem i assembly btpa N840_4383 ENOG4105DT3 PTS system, galactitol-specific IIc component N840_4384 ENOG4105K18 The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity) N840_4385 ENOG4105CN9 Peptidase m42 family protein N840_4387 ENOG4105DTA methyltransferase N840_4388 ENOG41080VW acetyltransferase N840_4393 ENOG4108MX5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity) N840_4394 ENOG41069FU Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria N840_4395 ENOG4108W9T type 1 fimbriae regulatory protein N840_4396 ENOG4105E71 FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off N840_4397 ENOG4108RQP Major type 1 subunit fimbrin N840_4398 ENOG4108S54 Fimbrial protein N840_4399 ENOG4108NAE Fimbrial chaperone protein N840_4400 ENOG4105CW0 outer membrane usher protein N840_4401 ENOG4108SQA Fimbrial N840_4402 ENOG4108T65 Fimbrial N840_4403 ENOG410643X FIMH SUBUNIT MANNOSE-sensitive type 1 fimbrial adhesin N840_4404 ENOG4107EFN gluconate transport system permease 3 N840_4406 ENOG4105DEI Mannitol dehydrogenase N840_4407 ENOG4105C6F GntR Family Transcriptional Regulator N840_4410 ENOG4107YNJ LysR family Transcriptional regulator N840_4411 ENOG4105DYB Isoaspartyl dipeptidase N840_4412 ENOG4108P2H Inner membrane protein YjiG N840_4413 ENOG41074DU domain protein N840_4415 ENOG4105CBP Major Facilitator N840_4416 ENOG4108ZK4 sdia-regulated domain-containing protein N840_4417 ENOG4105CIZ coA-substrate-specific enzyme activase N840_4418 ENOG4105DCU 2-hydroxyglutaryl-CoA dehydratase N840_4419 ENOG4106BRA Membrane N840_4420 ENOG41083G8 Multidrug resistance protein MdtM N840_4422 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family N840_4423 ENOG4106DIZ Domain of unknown function (DUF1127) N840_4426 ENOG4107SQC 5-methylcytosine-specific restriction enzyme subunit McrC N840_4427 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 N840_4430 ENOG4107XZC Restriction modification system DNA (Specificity N840_4431 ENOG4105CVR type I restriction-modification system N840_4432 ENOG4107SCJ type I restriction enzyme EcoKI subunit R N840_4433 ENOG4106H3A restriction N840_4434 ENOG4105CKI cobalamin synthesis protein N840_4435 ENOG4105VCD cytoplasmic protein N840_4436 ENOG4105D22 carbon starvation protein N840_4437 ENOG4105C8Q Methyl-accepting chemotaxis N840_4438 ENOG4108I5G Major Facilitator superfamily N840_4439 ENOG410617M Transcriptional regulator N840_4440 ENOG4105CPQ Dehydrogenase N840_4442 ENOG4105RI1 glycoprotein receptor N840_4443 ENOG4106CVF DNA replication protein N840_4446 ENOG4105DWK Membrane N840_4447 ENOG4108N8T regulatoR N840_4448 ENOG4108T94 DNA-binding transcriptional activator BglJ N840_4449 ENOG4108819 ferric iron reductase N840_4450 ENOG4105YBH Protein of unknown function (DUF1435) N840_4455 ENOG4108WPU DNA polymerase III subunit psi N840_4456 ENOG4105KEG ribosomal-protein-alanine acetyltransferase N840_4457 ENOG4105PAD Hydrolase N840_4459 ENOG4105K3G Periplasmic Protein N840_4461 ENOG4108NRW Phospholipase, patatin family N840_4462 ENOG4105EYA deoxyribonuclease N840_4463 ENOG41076CZ activating enzyme N840_4464 ENOG4105G0K glycine radical enzyme YjjI family N840_4469 ENOG4105EUP HipA domain protein N840_4471 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) N840_4472 ENOG4105EAC phosphoserine phosphatase N840_4473 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) N840_4474 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase N840_4475 ENOG4105C5H ABC transporter N840_4476 ENOG4107SC1 transglycosylase N840_4480 ENOG4105UEI Transcriptional Regulator AraC Family N840_4481 ENOG4108RH0 Crea protein N840_4482 ENOG4105E3W Two component transcriptional regulator (Winged helix family N840_4483 ENOG4105EB3 Histidine kinase N840_4484 ENOG4105CT7 inner membrane cred family protein N840_4485 ENOG41065U4 response regulator N840_4486 ENOG410759A N840_4487 ENOG4106FVC RNA methyltransferase N840_4488 ENOG4108I1J Integrase