locus-tag	class	description
ACETAC_00015	COG2501	S4 domain
ACETAC_00040	COG0187	DNA topoisomerase II activity
ACETAC_00045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACETAC_00050	COG0440	acetolactate synthase activity
ACETAC_00055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACETAC_00060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACETAC_00070	COG0066	3-isopropylmalate dehydratase activity
ACETAC_00075	COG0473	3-isopropylmalate dehydrogenase activity
ACETAC_00080	COG0129	dihydroxy-acid dehydratase activity
ACETAC_00085	COG0028	Belongs to the TPP enzyme family
ACETAC_00095	COG0307	riboflavin synthase, alpha
ACETAC_00105	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACETAC_00110	COG0628	permease
ACETAC_00135	COG1316	TRANSCRIPTIONal
ACETAC_00220	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ACETAC_00220	COG2199	diguanylate cyclase activity
ACETAC_00225	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACETAC_00230	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACETAC_00235	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACETAC_00280	COG1028	Short-chain dehydrogenase reductase Sdr
ACETAC_00285	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACETAC_00295	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ACETAC_00305	COG0460	homoserine dehydrogenase
ACETAC_00310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACETAC_00315	COG0083	homoserine kinase activity
ACETAC_00320	COG1982	Orn Lys Arg decarboxylase major
ACETAC_00330	COG3870	Protein conserved in bacteria
ACETAC_00345	COG1774	PSP1 C-terminal conserved region
ACETAC_00355	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ACETAC_00360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ACETAC_00365	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACETAC_00370	COG2002	toxin-antitoxin pair type II binding
ACETAC_00375	COG2715	membrane protein required for spore maturation
ACETAC_00380	COG0700	Nucleoside recognition
ACETAC_00385	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ACETAC_00385	COG0617	tRNA 3'-terminal CCA addition
ACETAC_00385	COG0517	IMP dehydrogenase activity
ACETAC_00390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACETAC_00390	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACETAC_00395	COG0084	hydrolase, TatD family'
ACETAC_00400	COG3584	3D domain protein
ACETAC_00400	COG3583	domain protein
ACETAC_00405	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACETAC_00415	COG0489	protein tyrosine kinase activity
ACETAC_00435	COG1131	(ABC) transporter
ACETAC_00510	COG1131	(ABC) transporter
ACETAC_00525	COG0534	Mate efflux family protein
ACETAC_00530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACETAC_00535	COG0708	Exodeoxyribonuclease III
ACETAC_00560	COG0425	Belongs to the sulfur carrier protein TusA family
ACETAC_00565	COG3383	formate dehydrogenase (NAD+) activity
ACETAC_00570	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
ACETAC_00585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACETAC_00590	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACETAC_00600	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACETAC_00605	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACETAC_00610	COG0745	RESPONSE REGULATOR receiver
ACETAC_00615	COG3850	Histidine kinase
ACETAC_00615	COG5002	protein histidine kinase activity
ACETAC_00620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACETAC_00630	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACETAC_00635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACETAC_00640	COG2002	toxin-antitoxin pair type II binding
ACETAC_00650	COG4466	Protein conserved in bacteria
ACETAC_00660	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACETAC_00675	COG0697	spore germination
ACETAC_00680	COG0814	amino acid
ACETAC_00695	COG1982	Orn Lys Arg decarboxylase major
ACETAC_00705	COG2959	enzyme of heme biosynthesis
ACETAC_00715	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ACETAC_00725	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ACETAC_00730	COG1793	dna ligase
ACETAC_00760	COG1518	maintenance of DNA repeat elements
ACETAC_00765	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ACETAC_00785	COG0018	arginyl-trna synthetase
ACETAC_00790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACETAC_00795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACETAC_00800	COG0352	thiamine-phosphate diphosphorylase activity
ACETAC_00805	COG0640	Transcriptional regulator
ACETAC_00810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ACETAC_00815	COG0628	permease
ACETAC_00845	COG0791	NLP P60 protein
ACETAC_00845	COG3883	PFAM NLP P60 protein
ACETAC_00855	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ACETAC_00855	COG1796	DNA polymerase
ACETAC_00860	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACETAC_00870	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACETAC_00875	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACETAC_00880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACETAC_00885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACETAC_00900	COG0586	Pfam SNARE associated Golgi protein
ACETAC_00905	COG2205	protein histidine kinase activity
ACETAC_00910	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ACETAC_00915	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACETAC_00920	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACETAC_00930	COG5002	protein histidine kinase activity
ACETAC_00935	COG0745	RESPONSE REGULATOR receiver
ACETAC_00940	COG1523	belongs to the glycosyl hydrolase 13 family
ACETAC_00990	COG3693	PFAM glycoside hydrolase, family 10
ACETAC_00995	COG3693	PFAM glycoside hydrolase, family 10
ACETAC_01080	COG3693	PFAM glycoside hydrolase, family 10
ACETAC_01085	COG3693	PFAM glycoside hydrolase, family 10
ACETAC_01090	COG3693	PFAM glycoside hydrolase, family 10
ACETAC_01100	COG1518	maintenance of DNA repeat elements
ACETAC_01105	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ACETAC_01115	COG1027	Aspartate ammonia-lyase
ACETAC_01120	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACETAC_01130	COG3956	TIGRFAM MazG family protein
ACETAC_01140	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ACETAC_01145	COG2385	sporulation resulting in formation of a cellular spore
ACETAC_01155	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
ACETAC_01180	COG1098	S1 RNA binding domain
ACETAC_01255	COG0577	efflux transmembrane transporter activity
ACETAC_01255	COG1136	(ABC) transporter
ACETAC_01300	COG3266	domain, Protein
ACETAC_01300	COG2911	Protein conserved in bacteria
ACETAC_01300	COG1361	Conserved repeat domain
ACETAC_01305	COG1714	RDD family
ACETAC_01445	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ACETAC_01445	COG2199	diguanylate cyclase activity
ACETAC_01460	COG1714	RDD family
ACETAC_01570	COG3693	PFAM glycoside hydrolase, family 10
ACETAC_01585	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ACETAC_01590	COG1451	nucleotide metabolic process
ACETAC_01595	COG0318	PFAM AMP-dependent synthetase and ligase
ACETAC_01600	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACETAC_01600	COG2247	cell wall binding repeat
ACETAC_01610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACETAC_01625	COG3830	Belongs to the UPF0237 family
ACETAC_01645	COG1131	(ABC) transporter
ACETAC_01650	COG1846	Transcriptional regulator
ACETAC_01655	COG1785	Belongs to the alkaline phosphatase family
ACETAC_01665	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ACETAC_01675	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACETAC_01675	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACETAC_01685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACETAC_01695	COG2337	Toxic component of a toxin-antitoxin (TA) module
ACETAC_01715	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ACETAC_01720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACETAC_01730	COG0004	ammonium transporteR
ACETAC_01740	COG0004	ammonium transporteR
ACETAC_01745	COG0347	Belongs to the P(II) protein family
ACETAC_01750	COG0205	6-phosphofructokinase activity
ACETAC_01900	COG0009	L-threonylcarbamoyladenylate synthase
ACETAC_01905	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACETAC_01910	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ACETAC_01920	COG2873	o-acetylhomoserine
ACETAC_01925	COG3459	Glycosyltransferase 36 associated
ACETAC_01930	COG0840	transmembrane signaling receptor activity
ACETAC_01955	COG2385	sporulation resulting in formation of a cellular spore
ACETAC_01960	COG0739	heme binding
ACETAC_01965	COG1609	Transcriptional regulator
ACETAC_01970	COG1077	Cell shape determining protein MreB Mrl
ACETAC_01975	COG4786	Flagellar basal body rod
ACETAC_01990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACETAC_02005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACETAC_02010	COG1993	acr, cog1993
ACETAC_02020	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ACETAC_02025	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACETAC_02035	COG0297	glycogen (starch) synthase activity
ACETAC_02045	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ACETAC_02050	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ACETAC_02055	COG0297	glycogen (starch) synthase activity
ACETAC_02060	COG0058	SHG alpha-glucan phosphorylase activity
ACETAC_02105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACETAC_02110	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACETAC_02120	COG0586	Pfam SNARE associated Golgi protein
ACETAC_02130	COG3879	Bacterial protein of unknown function (DUF881)
ACETAC_02145	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACETAC_02155	COG0436	Aminotransferase
ACETAC_02165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACETAC_02175	COG0495	leucyl-tRNA aminoacylation
ACETAC_02180	COG4086	secreted protein
ACETAC_02185	COG0574	Belongs to the PEP-utilizing enzyme family
ACETAC_02185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACETAC_02190	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ACETAC_02195	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACETAC_02200	COG4632	Exopolysaccharide biosynthesis protein
ACETAC_02200	COG5434	Belongs to the glycosyl hydrolase 28 family
ACETAC_02215	COG0646	methionine synthase
ACETAC_02215	COG1410	methionine synthase
ACETAC_02220	COG1980	fructose-bisphosphate aldolase activity
ACETAC_02235	COG1342	Belongs to the UPF0251 family
ACETAC_02250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACETAC_02250	COG0731	radical SAM domain protein
ACETAC_02270	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACETAC_02275	COG2255	four-way junction helicase activity
ACETAC_02280	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACETAC_02290	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACETAC_02290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACETAC_02295	COG0511	ligase activity, forming carbon-carbon bonds
ACETAC_02295	COG5016	pyruvate
ACETAC_02300	COG0439	Biotin carboxylase
ACETAC_02305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACETAC_02310	COG1116	anion transmembrane transporter activity
ACETAC_02315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACETAC_02340	COG0789	Transcriptional regulator
ACETAC_02400	COG0463	Glycosyl transferase, family 2
ACETAC_02420	COG1091	dTDP-4-dehydrorhamnose reductase activity
ACETAC_02495	COG3012	SEC-C Motif Domain Protein
ACETAC_02505	COG4115	mRNA cleavage
ACETAC_02550	COG1309	transcriptional regulator
ACETAC_02555	COG1511	domain protein
ACETAC_02560	COG0622	Phosphoesterase
ACETAC_02580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACETAC_02590	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACETAC_02595	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACETAC_02600	COG2720	vancomycin resistance protein
ACETAC_02605	COG0735	belongs to the Fur family
ACETAC_02610	COG0561	phosphatase activity
ACETAC_02620	COG0126	phosphoglycerate kinase activity
ACETAC_02630	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACETAC_02635	COG0148	phosphopyruvate hydratase activity
ACETAC_02645	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACETAC_02650	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ACETAC_02655	COG0358	DNA primase activity
ACETAC_02660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACETAC_02670	COG2384	SAM-dependent methyltransferase
ACETAC_02675	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACETAC_02685	COG0482	sulfurtransferase activity
ACETAC_02695	COG1482	cell wall glycoprotein biosynthetic process
ACETAC_02730	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACETAC_02735	COG1268	BioY protein
ACETAC_02740	COG0525	valine-tRNA ligase activity
ACETAC_02760	COG0351	phosphomethylpyrimidine kinase
ACETAC_02760	COG0352	thiamine-phosphate diphosphorylase activity
ACETAC_02785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACETAC_02790	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ACETAC_02795	COG1151	hydroxylamine reductase activity
ACETAC_02800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACETAC_02815	COG2171	N-acyltransferase activity
ACETAC_02820	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACETAC_02830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACETAC_02840	COG0174	glutamine synthetase
ACETAC_02850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACETAC_02860	COG0457	Tetratricopeptide repeat
ACETAC_02860	COG0463	Glycosyl transferase, family 2
ACETAC_02865	COG0438	transferase activity, transferring glycosyl groups
ACETAC_02880	COG0739	heme binding
ACETAC_02900	COG0616	signal peptide processing
ACETAC_02905	COG4475	Protein of unknown function (DUF436)
ACETAC_02920	COG1983	PspC domain protein
ACETAC_02935	COG1113	amino acid transport
ACETAC_02950	COG0237	dephospho-CoA kinase activity
ACETAC_02955	COG0741	lytic transglycosylase activity
ACETAC_02960	COG0352	thiamine-phosphate diphosphorylase activity
ACETAC_02975	COG0791	NLP P60 protein
ACETAC_02980	COG1217	gtp-binding protein TYPA
ACETAC_02985	COG0741	lytic transglycosylase activity
ACETAC_03005	COG2003	Belongs to the UPF0758 family
ACETAC_03010	COG1077	Cell shape determining protein MreB Mrl
ACETAC_03035	COG2894	cell division
ACETAC_03045	COG2205	protein histidine kinase activity
ACETAC_03045	COG3292	Two component regulator propeller
ACETAC_03045	COG0745	RESPONSE REGULATOR receiver
ACETAC_03060	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACETAC_03065	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACETAC_03070	COG1846	Transcriptional regulator
ACETAC_03080	COG1132	(ABC) transporter
ACETAC_03085	COG0426	domain, Protein
ACETAC_03090	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ACETAC_03105	COG0438	transferase activity, transferring glycosyl groups
ACETAC_03110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACETAC_03115	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ACETAC_03120	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACETAC_03125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACETAC_03130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACETAC_03135	COG0072	phenylalanine-tRNA ligase activity
ACETAC_03135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACETAC_03145	COG1193	negative regulation of DNA recombination
ACETAC_03150	COG1683	Conserved Protein
ACETAC_03155	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACETAC_03185	COG1362	aminopeptidase activity
ACETAC_03200	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ACETAC_03200	COG2199	diguanylate cyclase activity
ACETAC_03205	COG0840	transmembrane signaling receptor activity
ACETAC_03205	COG3290	protein histidine kinase activity
ACETAC_03225	COG0438	transferase activity, transferring glycosyl groups
ACETAC_03250	COG0012	GTP binding
ACETAC_03260	COG0612	Peptidase, M16
ACETAC_03265	COG0612	Peptidase, M16
ACETAC_03285	COG0768	penicillin binding
ACETAC_03290	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACETAC_03295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACETAC_03310	COG0772	Belongs to the SEDS family
ACETAC_03320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACETAC_03325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACETAC_03330	COG3879	Bacterial protein of unknown function (DUF881)
ACETAC_03335	COG3856	small basic protein
ACETAC_03345	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACETAC_03355	COG1191	sigma factor activity
ACETAC_03360	COG1191	sigma factor activity
ACETAC_03365	COG0789	Transcriptional regulator
ACETAC_03375	COG1873	PFAM PRC-barrel domain
ACETAC_03380	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACETAC_03385	COG0745	RESPONSE REGULATOR receiver
ACETAC_03390	COG5002	protein histidine kinase activity
ACETAC_03395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACETAC_03400	COG0573	inorganic phosphate transmembrane transporter activity
ACETAC_03405	COG0581	inorganic phosphate transmembrane transporter activity
ACETAC_03410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACETAC_03415	COG0704	Plays a role in the regulation of phosphate uptake
ACETAC_03450	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ACETAC_03460	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ACETAC_03525	COG1592	Rubrerythrin
ACETAC_03530	COG0450	alkyl hydroperoxide reductase
ACETAC_03535	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACETAC_03565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACETAC_03570	COG1040	competence protein
ACETAC_03590	COG4786	Flagellar basal body rod
ACETAC_03590	COG1256	bacterial-type flagellum assembly
ACETAC_03595	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACETAC_03605	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ACETAC_03610	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ACETAC_03615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACETAC_03620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACETAC_03635	COG0463	Glycosyl transferase, family 2
ACETAC_03635	COG0457	Tetratricopeptide repeat
ACETAC_03645	COG3069	C4-dicarboxylate transmembrane transporter activity
ACETAC_03650	COG5434	Belongs to the glycosyl hydrolase 28 family
ACETAC_03650	COG4632	Exopolysaccharide biosynthesis protein
ACETAC_03665	COG1164	Oligoendopeptidase f
ACETAC_03675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACETAC_03680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACETAC_03685	COG1120	ATPase activity
ACETAC_03715	COG3842	ATPase activity
ACETAC_03720	COG1605	Chorismate mutase
ACETAC_03720	COG0077	Prephenate dehydratase
ACETAC_03725	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ACETAC_03730	COG0287	Prephenate dehydrogenase
ACETAC_03740	COG0745	RESPONSE REGULATOR receiver
ACETAC_03745	COG5002	protein histidine kinase activity
ACETAC_03750	COG3773	Cell wall hydrolase
ACETAC_03755	COG2119	membrane
ACETAC_03760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACETAC_03765	COG1704	LemA family
ACETAC_03770	COG0501	Belongs to the peptidase M48B family
ACETAC_03785	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ACETAC_03790	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ACETAC_03805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACETAC_03810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACETAC_03815	COG3949	Membrane
ACETAC_03825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACETAC_03845	COG0671	phosphoesterase, PA-phosphatase related
ACETAC_03850	COG1105	Belongs to the carbohydrate kinase PfkB family
ACETAC_03860	COG1704	LemA family
ACETAC_03870	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ACETAC_03875	COG1278	Cold shock
ACETAC_03950	COG2814	Major facilitator Superfamily
ACETAC_03960	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACETAC_03965	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACETAC_03970	COG0564	pseudouridine synthase activity
ACETAC_03995	COG1459	type II secretion system
ACETAC_04000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACETAC_04035	COG0741	lytic transglycosylase activity
ACETAC_04055	COG1528	Iron-storage protein
ACETAC_04060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACETAC_04070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACETAC_04075	COG1121	(ABC) transporter
ACETAC_04080	COG0803	Belongs to the bacterial solute-binding protein 9 family
ACETAC_04085	COG0735	belongs to the Fur family
ACETAC_04090	COG2314	TM2 domain
ACETAC_04130	COG0789	Transcriptional regulator
ACETAC_04185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACETAC_04195	COG3266	domain, Protein
ACETAC_04195	COG2911	Protein conserved in bacteria
ACETAC_04195	COG1361	Conserved repeat domain
ACETAC_04215	COG0419	ATPase involved in DNA repair
ACETAC_04225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACETAC_04250	COG0436	Aminotransferase
ACETAC_04255	COG1522	sequence-specific DNA binding
ACETAC_04260	COG1797	cobyrinic acid a,c-diamide synthase activity
ACETAC_04285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACETAC_04290	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ACETAC_04340	COG2099	Precorrin-6x reductase
ACETAC_04345	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACETAC_04350	COG0181	hydroxymethylbilane synthase activity
ACETAC_04370	COG3546	catalase activity
ACETAC_04395	COG0166	Belongs to the GPI family
ACETAC_04400	COG0058	SHG alpha-glucan phosphorylase activity
ACETAC_04405	COG1012	belongs to the aldehyde dehydrogenase family
ACETAC_04425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACETAC_04430	COG0437	4 iron, 4 sulfur cluster binding
ACETAC_04440	COG0067	glutamate synthase
ACETAC_04445	COG2884	Cell division ATP-binding protein ftsE
ACETAC_04450	COG2177	Part of the ABC transporter FtsEX involved in
ACETAC_04455	COG4942	peptidase
ACETAC_04460	COG0793	Belongs to the peptidase S41A family
ACETAC_04460	COG3409	Peptidoglycan-binding domain 1 protein
ACETAC_04465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACETAC_04470	COG0556	nucleotide-excision repair
ACETAC_04500	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ACETAC_04500	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ACETAC_04505	COG0803	Belongs to the bacterial solute-binding protein 9 family
ACETAC_04510	COG1121	(ABC) transporter
ACETAC_04520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACETAC_04545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACETAC_04580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACETAC_04590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACETAC_04605	COG0768	penicillin binding
ACETAC_04610	COG0671	phosphoesterase, PA-phosphatase related
ACETAC_04635	COG1426	Protein conserved in bacteria
ACETAC_04650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACETAC_04685	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACETAC_04705	COG1773	rubredoxin
ACETAC_04705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACETAC_04710	COG1773	rubredoxin
ACETAC_04710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACETAC_04715	COG2217	Heavy metal translocating P-type atpase
ACETAC_04720	COG1122	ATPase activity
ACETAC_04745	COG0481	GTPase activity
ACETAC_04750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACETAC_04760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACETAC_04765	COG0443	Heat shock 70 kDa protein
ACETAC_04770	COG0484	heat shock protein binding
ACETAC_04775	COG2264	protein methyltransferase activity
ACETAC_04780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACETAC_04785	COG0789	Transcriptional regulator
ACETAC_04795	COG0537	adenosine 5'-monophosphoramidase activity
ACETAC_04825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACETAC_04835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACETAC_04840	COG1120	ATPase activity
ACETAC_04850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACETAC_04870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACETAC_04880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACETAC_04885	COG1120	ATPase activity
ACETAC_04895	COG0500	methyltransferase
ACETAC_04930	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ACETAC_04935	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ACETAC_04935	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ACETAC_04945	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACETAC_04960	COG3599	regulation of cell shape
ACETAC_04975	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACETAC_05020	COG1404	Belongs to the peptidase S8 family
ACETAC_05045	COG0512	Glutamine amidotransferase of anthranilate synthase
ACETAC_05045	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACETAC_05055	COG0134	indole-3-glycerol-phosphate synthase activity
ACETAC_05060	COG0135	phosphoribosylanthranilate isomerase activity
ACETAC_05065	COG0133	tryptophan synthase activity
ACETAC_05090	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ACETAC_05100	COG3447	MASE1 domain protein
ACETAC_05100	COG5001	Diguanylate cyclase
ACETAC_05100	COG5002	protein histidine kinase activity
ACETAC_05115	COG1966	Carbon starvation protein
ACETAC_05120	COG3279	Response regulator of the LytR AlgR family
ACETAC_05125	COG3275	phosphorelay sensor kinase activity
ACETAC_05130	COG0602	queuosine metabolic process
ACETAC_05135	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACETAC_05140	COG0840	transmembrane signaling receptor activity
ACETAC_05155	COG1595	DNA-templated transcription, initiation
ACETAC_05165	COG1131	(ABC) transporter
ACETAC_05195	COG0528	UMP kinase activity
ACETAC_05200	COG0233	cytoplasmic translational termination
ACETAC_05210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACETAC_05215	COG4589	Belongs to the CDS family
ACETAC_05225	COG0750	zinc metalloprotease
ACETAC_05230	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ACETAC_05235	COG0463	Glycosyl transferase, family 2
ACETAC_05240	COG2176	DNA-directed DNA polymerase activity
ACETAC_05250	COG0195	Participates in both transcription termination and antitermination
ACETAC_05255	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ACETAC_05265	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACETAC_05270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACETAC_05275	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ACETAC_05280	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACETAC_05285	COG0196	riboflavin kinase activity
ACETAC_05290	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACETAC_05295	COG1185	polyribonucleotide nucleotidyltransferase activity
ACETAC_05305	COG0756	dUTP diphosphatase activity
ACETAC_05315	COG0527	aspartate kinase activity
ACETAC_05320	COG0740	serine-type endopeptidase activity
ACETAC_05330	COG1674	ftsk spoiiie
ACETAC_05335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACETAC_05340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACETAC_05350	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACETAC_05360	COG0789	Transcriptional regulator
ACETAC_05385	COG0420	3'-5' exonuclease activity
ACETAC_05390	COG0419	ATPase involved in DNA repair
ACETAC_05400	COG1692	metallophosphoesterase
ACETAC_05405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACETAC_05410	COG0586	Pfam SNARE associated Golgi protein
ACETAC_05420	COG2359	stage V sporulation protein S
ACETAC_05425	COG0613	PHP domain protein
ACETAC_05430	COG0436	Aminotransferase
ACETAC_05440	COG0464	growth
ACETAC_05445	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ACETAC_05465	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACETAC_05475	COG0454	-acetyltransferase
ACETAC_05485	COG1187	pseudouridine synthase activity
ACETAC_05505	COG3942	CHAP domain
ACETAC_05505	COG1388	LysM domain
ACETAC_05520	COG1737	Transcriptional regulator
ACETAC_05525	COG0406	alpha-ribazole phosphatase activity
ACETAC_05530	COG2081	HI0933 family
ACETAC_05545	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACETAC_05550	COG0204	Acyl-transferase
ACETAC_05565	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACETAC_05575	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ACETAC_05580	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACETAC_05595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACETAC_05600	COG0328	RNA-DNA hybrid ribonuclease activity
ACETAC_05620	COG4974	Belongs to the 'phage' integrase family
ACETAC_05625	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACETAC_05630	COG0577	efflux transmembrane transporter activity
ACETAC_05645	COG1136	(ABC) transporter
ACETAC_05650	COG1132	(ABC) transporter
ACETAC_05660	COG1131	(ABC) transporter
ACETAC_05675	COG0535	radical SAM domain protein
ACETAC_05685	COG2197	response regulator
ACETAC_05730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACETAC_05955	COG1266	CAAX protease self-immunity
ACETAC_05985	COG0445	tRNA wobble uridine modification
ACETAC_05995	COG1686	Belongs to the peptidase S11 family
ACETAC_06000	COG3874	Sporulation protein YtfJ
ACETAC_06010	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACETAC_06020	COG1994	Peptidase M50
ACETAC_06025	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ACETAC_06025	COG0617	tRNA 3'-terminal CCA addition
ACETAC_06025	COG0517	IMP dehydrogenase activity
ACETAC_06050	COG0789	Transcriptional regulator
ACETAC_06055	COG3360	Dodecin
ACETAC_06060	COG1191	sigma factor activity
ACETAC_06070	COG1366	Belongs to the anti-sigma-factor antagonist family
ACETAC_06075	COG1686	Belongs to the peptidase S11 family
ACETAC_06080	COG4399	Belongs to the UPF0754 family
ACETAC_06090	COG1379	DNA repair
ACETAC_06095	COG0494	nUDIX hydrolase
ACETAC_06110	COG0463	Glycosyl transferase, family 2
ACETAC_06135	COG0750	zinc metalloprotease
ACETAC_06140	COG0497	DNA recombination
ACETAC_06145	COG1438	arginine binding
ACETAC_06155	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ACETAC_06160	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACETAC_06180	COG1570	exodeoxyribonuclease VII activity
ACETAC_06200	COG1302	Protein conserved in bacteria
ACETAC_06240	COG3854	ATPases associated with a variety of cellular activities
ACETAC_06255	COG0006	proline dipeptidase activity
ACETAC_06265	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACETAC_06320	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ACETAC_06330	COG1459	type II secretion system
ACETAC_06340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACETAC_06345	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACETAC_06350	COG0546	phosphoglycolate phosphatase activity
ACETAC_06360	COG0768	penicillin binding
ACETAC_06365	COG0826	peptidase U32
ACETAC_06375	COG4122	O-methyltransferase activity
ACETAC_06380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACETAC_06390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ACETAC_06395	COG0735	belongs to the Fur family
ACETAC_06400	COG3906	Belongs to the UPF0473 family
ACETAC_06410	COG4472	Bacterial protein of unknown function (DUF965)
ACETAC_06420	COG0628	permease
ACETAC_06440	COG1959	2 iron, 2 sulfur cluster binding
ACETAC_06490	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACETAC_06500	COG0577	efflux transmembrane transporter activity
ACETAC_06500	COG1136	(ABC) transporter
ACETAC_06565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACETAC_06570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACETAC_06580	COG1937	Protein conserved in bacteria
ACETAC_06590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACETAC_06625	COG1191	sigma factor activity
ACETAC_06630	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ACETAC_06635	COG1776	CheC inhibitor of MCP methylation
ACETAC_06640	COG0835	chemotaxis
ACETAC_06645	COG2198	Histidine kinase
ACETAC_06645	COG0643	Histidine kinase
ACETAC_06655	COG0455	bacterial-type flagellum organization
ACETAC_06660	COG1419	protein localization to endoplasmic reticulum
ACETAC_06665	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACETAC_06670	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACETAC_06675	COG1684	flagellar biosynthetic protein fliR
ACETAC_06680	COG1987	bacterial-type flagellum assembly
ACETAC_06685	COG1338	Plays a role in the flagellum-specific transport system
ACETAC_06695	COG2201	protein-glutamate methylesterase activity
ACETAC_06700	COG1776	CheC inhibitor of MCP methylation
ACETAC_06700	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACETAC_06705	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACETAC_06715	COG1582	Flagellar protein (FlbD)
ACETAC_06730	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ACETAC_06750	COG1157	protein secretion by the type III secretion system
ACETAC_06760	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACETAC_06770	COG1677	Flagellar hook-basal body complex protein FliE
ACETAC_06780	COG1815	bacterial-type flagellum-dependent cell motility
ACETAC_06790	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ACETAC_06800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACETAC_06805	COG0758	DNA mediated transformation
ACETAC_06810	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACETAC_06815	COG0792	nuclease activity
ACETAC_06850	COG0180	Tryptophanyl-tRNA synthetase
ACETAC_06855	COG0606	chelatase, subunit chli
ACETAC_06860	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ACETAC_06870	COG0336	Belongs to the RNA methyltransferase TrmD family
ACETAC_06880	COG1837	Belongs to the UPF0109 family
ACETAC_06890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACETAC_06895	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ACETAC_06900	COG0552	protein localization to endoplasmic reticulum
ACETAC_06905	COG1196	nuclear chromosome segregation
ACETAC_06910	COG2359	stage V sporulation protein S
ACETAC_06920	COG0571	ribonuclease III activity
ACETAC_06925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACETAC_06935	COG1028	Short-chain dehydrogenase reductase Sdr
ACETAC_06940	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACETAC_06945	COG2070	2-Nitropropane dioxygenase
ACETAC_06950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACETAC_06955	COG0416	fatty acid biosynthetic process
ACETAC_06960	COG2030	dehydratase
ACETAC_06965	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACETAC_06975	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACETAC_06980	COG0280	phosphate acetyltransferase
ACETAC_06985	COG1323	Belongs to the UPF0348 family
ACETAC_06990	COG3314	Sporulation integral membrane protein YlbJ
ACETAC_07000	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACETAC_07005	COG0742	ribosomal rna small subunit methyltransferase
ACETAC_07020	COG1307	EDD domain protein, DegV family
ACETAC_07025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACETAC_07030	COG1461	Dihydroxyacetone kinase
ACETAC_07035	COG1302	Protein conserved in bacteria
ACETAC_07065	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACETAC_07070	COG1162	GTPase activity
ACETAC_07075	COG0515	serine threonine protein kinase
ACETAC_07075	COG2815	serine threonine protein kinase
ACETAC_07080	COG0631	protein serine/threonine phosphatase activity
ACETAC_07090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACETAC_07090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACETAC_07095	COG2738	Putative neutral zinc metallopeptidase
ACETAC_07105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACETAC_07115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACETAC_07120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACETAC_07125	COG1758	RNA polymerase activity
ACETAC_07130	COG0194	GDP metabolic process
ACETAC_07135	COG2052	Domain of unknown function (DUF370)
ACETAC_07140	COG1561	YicC-like family, N-terminal region
ACETAC_07145	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ACETAC_07160	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ACETAC_07205	COG3547	Transposase (IS116 IS110 IS902 family)
ACETAC_07235	COG0543	2 iron, 2 sulfur cluster binding
ACETAC_07240	COG0284	orotidine-5'-phosphate decarboxylase activity
ACETAC_07250	COG0540	Belongs to the ATCase OTCase family
ACETAC_07265	COG0367	asparagine synthase
ACETAC_07270	COG0745	RESPONSE REGULATOR receiver
ACETAC_07275	COG5002	protein histidine kinase activity
ACETAC_07280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACETAC_07290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACETAC_07295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACETAC_07305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACETAC_07425	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ACETAC_07425	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACETAC_07435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACETAC_07440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACETAC_07475	COG2385	sporulation resulting in formation of a cellular spore
ACETAC_07475	COG2247	cell wall binding repeat
ACETAC_07495	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ACETAC_07505	COG0835	chemotaxis
ACETAC_07510	COG0217	transcriptional regulatory protein
ACETAC_07515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACETAC_07520	COG0730	response to heat
ACETAC_07530	COG1739	Uncharacterized protein family UPF0029
ACETAC_07535	COG0494	nUDIX hydrolase
ACETAC_07545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACETAC_07585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACETAC_07595	COG4555	ABC transporter
ACETAC_07605	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ACETAC_07615	COG0268	Binds directly to 16S ribosomal RNA
ACETAC_07625	COG0658	competence protein
ACETAC_07625	COG2333	competence protein COMEC
ACETAC_07645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACETAC_07670	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACETAC_07690	COG2078	PFAM AMMECR1 domain protein
ACETAC_07690	COG3885	ferrous iron binding
ACETAC_07695	COG3118	belongs to the thioredoxin family
ACETAC_07700	COG1982	Orn Lys Arg decarboxylase major
ACETAC_07705	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACETAC_07710	COG0477	Major facilitator Superfamily
ACETAC_07715	COG0789	Transcriptional regulator
ACETAC_07730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACETAC_07735	COG2226	methyltransferase
ACETAC_07740	COG2226	methyltransferase
ACETAC_07745	COG4608	Belongs to the ABC transporter superfamily
ACETAC_07750	COG0444	Belongs to the ABC transporter superfamily
ACETAC_07755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACETAC_07760	COG0601	transmembrane transport
ACETAC_07775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACETAC_07780	COG0747	negative chemotaxis
ACETAC_07790	COG4608	Belongs to the ABC transporter superfamily
ACETAC_07795	COG0444	Belongs to the ABC transporter superfamily
ACETAC_07800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACETAC_07805	COG0601	transmembrane transport
ACETAC_07810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACETAC_07815	COG0747	negative chemotaxis
ACETAC_07840	COG0531	amino acid
ACETAC_07850	COG0432	Pfam Uncharacterised protein family UPF0047
ACETAC_07855	COG0116	Belongs to the methyltransferase superfamily
ACETAC_07870	COG1924	4 iron, 4 sulfur cluster binding
ACETAC_07910	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACETAC_07920	COG1968	undecaprenyl-diphosphatase activity
ACETAC_07930	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACETAC_07935	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACETAC_07975	COG0557	exoribonuclease II activity
ACETAC_07980	COG0423	glycine-tRNA ligase activity
ACETAC_07990	COG1381	Involved in DNA repair and RecF pathway recombination
ACETAC_08005	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACETAC_08015	COG1702	phosphate starvation-inducible protein PhoH
ACETAC_08040	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACETAC_08055	COG1131	(ABC) transporter
ACETAC_08060	COG1120	ATPase activity
ACETAC_08070	COG4822	anaerobic cobalamin biosynthetic process
ACETAC_08090	COG0789	Transcriptional regulator
ACETAC_08105	COG1921	L-seryl-tRNASec selenium transferase activity
ACETAC_08115	COG1596	polysaccharide export
ACETAC_08115	COG1555	photosystem II stabilization
ACETAC_08120	COG1686	Belongs to the peptidase S11 family
ACETAC_08130	COG0799	negative regulation of ribosome biogenesis
ACETAC_08135	COG1713	HD superfamily hydrolase involved in NAD metabolism
ACETAC_08145	COG0675	Transposase, IS605 OrfB family
ACETAC_08195	COG0517	IMP dehydrogenase activity
ACETAC_08195	COG1994	Peptidase M50
ACETAC_08210	COG0730	response to heat
ACETAC_08225	COG0772	Belongs to the SEDS family
ACETAC_08245	COG0772	Belongs to the SEDS family
ACETAC_08260	COG1968	undecaprenyl-diphosphatase activity
ACETAC_08265	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ACETAC_08275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACETAC_08280	COG0352	thiamine-phosphate diphosphorylase activity
ACETAC_08290	COG2022	thiamine diphosphate biosynthetic process
ACETAC_08295	COG2104	thiamine diphosphate biosynthetic process
ACETAC_08295	COG2022	thiamine diphosphate biosynthetic process
ACETAC_08315	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACETAC_08320	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACETAC_08325	COG4149	molybdate abc transporter
ACETAC_08335	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACETAC_08340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACETAC_08345	COG1120	ATPase activity
ACETAC_08355	COG2226	methyltransferase
ACETAC_08370	COG3383	formate dehydrogenase (NAD+) activity
ACETAC_08390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACETAC_08400	COG0561	phosphatase activity
ACETAC_08405	COG2323	membrane
ACETAC_08425	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACETAC_08435	COG0726	polysaccharide deacetylase
ACETAC_08440	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACETAC_08445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACETAC_08455	COG0295	cytidine deaminase activity
ACETAC_08465	COG0538	isocitrate dehydrogenase activity
ACETAC_08470	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACETAC_08470	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACETAC_08470	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACETAC_08470	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACETAC_08475	COG0113	porphobilinogen synthase activity
ACETAC_08480	COG1648	precorrin-2 dehydrogenase activity
ACETAC_08480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACETAC_08485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACETAC_08495	COG1215	transferase activity, transferring glycosyl groups
ACETAC_08515	COG0728	peptidoglycan biosynthetic process
ACETAC_08520	COG1074	ATP-dependent DNA helicase activity
ACETAC_08525	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ACETAC_08540	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACETAC_08595	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACETAC_08600	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACETAC_08605	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACETAC_08610	COG4608	Belongs to the ABC transporter superfamily
ACETAC_08615	COG0444	Belongs to the ABC transporter superfamily
ACETAC_08620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACETAC_08625	COG0601	transmembrane transport
ACETAC_08630	COG4166	transmembrane transport
ACETAC_08635	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACETAC_08640	COG0154	amidase activity
ACETAC_08650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACETAC_08655	COG0210	DNA helicase
ACETAC_08660	COG4496	protein, YerC YecD
ACETAC_08665	COG2244	polysaccharide biosynthetic process
ACETAC_08670	COG1854	S-ribosylhomocysteine lyase activity
ACETAC_08675	COG1473	amidohydrolase
ACETAC_08695	COG0151	Belongs to the GarS family
ACETAC_08700	COG0138	bifunctional purine biosynthesis protein purh
ACETAC_08705	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACETAC_08710	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACETAC_08715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACETAC_08720	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ACETAC_08725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACETAC_08730	COG2252	PERMEase
ACETAC_08735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACETAC_08735	COG0519	Catalyzes the synthesis of GMP from XMP
ACETAC_08740	COG0516	GMP reductase activity
ACETAC_08740	COG0517	IMP dehydrogenase activity
ACETAC_08770	COG1404	Belongs to the peptidase S8 family
ACETAC_08780	COG4120	Belongs to the binding-protein-dependent transport system permease family
ACETAC_08825	COG1811	Na channel or pump
ACETAC_08840	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ACETAC_08850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACETAC_08855	COG0488	(ABC) transporter
ACETAC_08875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACETAC_08895	COG1328	CTP reductase activity
ACETAC_08895	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACETAC_08900	COG0735	belongs to the Fur family
ACETAC_08920	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ACETAC_08920	COG1918	ferrous iron import across plasma membrane
ACETAC_08940	COG1234	tRNA 3'-trailer cleavage
ACETAC_08975	COG0864	Transcriptional regulator
ACETAC_08980	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ACETAC_08980	COG1918	ferrous iron import across plasma membrane
ACETAC_08990	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACETAC_08995	COG0456	acetyltransferase
ACETAC_09000	COG1214	PFAM Peptidase M22, glycoprotease
ACETAC_09005	COG0802	atpase or kinase
ACETAC_09020	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACETAC_09030	COG0398	Pfam SNARE associated Golgi protein
ACETAC_09035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACETAC_09045	COG0653	protein targeting
ACETAC_09080	COG1516	flagellar protein fliS
ACETAC_09085	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ACETAC_09110	COG0367	asparagine synthase
ACETAC_09130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACETAC_09135	COG0140	phosphoribosyl-ATP diphosphatase activity
ACETAC_09135	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACETAC_09150	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACETAC_09155	COG0131	Imidazoleglycerol-phosphate dehydratase
ACETAC_09165	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACETAC_09175	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ACETAC_09185	COG1361	Conserved repeat domain
ACETAC_09190	COG3266	domain, Protein
ACETAC_09190	COG2911	Protein conserved in bacteria
ACETAC_09190	COG1361	Conserved repeat domain
ACETAC_09195	COG0542	response to heat
ACETAC_09200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACETAC_09210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACETAC_09215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACETAC_09220	COG0590	tRNA wobble adenosine to inosine editing
ACETAC_09235	COG0009	L-threonylcarbamoyladenylate synthase
ACETAC_09250	COG2890	protein-(glutamine-N5) methyltransferase activity
ACETAC_09255	COG3872	metal-dependent enzyme
ACETAC_09260	COG0254	rRNA binding
ACETAC_09265	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACETAC_09290	COG2246	polysaccharide biosynthetic process
ACETAC_09295	COG0463	Glycosyl transferase, family 2
ACETAC_09335	COG0504	CTP synthase activity
ACETAC_09340	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ACETAC_09345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACETAC_09350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACETAC_09355	COG3409	Peptidoglycan-binding domain 1 protein
ACETAC_09355	COG0793	Belongs to the peptidase S41A family
ACETAC_09370	COG1573	uracil-dna glycosylase
ACETAC_09385	COG0513	Belongs to the DEAD box helicase family
ACETAC_09395	COG1073	alpha beta
ACETAC_09395	COG2226	methyltransferase
ACETAC_09400	COG0156	8-amino-7-oxononanoate synthase activity
ACETAC_09410	COG1396	sequence-specific DNA binding
ACETAC_09415	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACETAC_09425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACETAC_09430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACETAC_09450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACETAC_09455	COG2226	methyltransferase
ACETAC_09460	COG2226	methyltransferase
ACETAC_09465	COG4608	Belongs to the ABC transporter superfamily
ACETAC_09470	COG0444	Belongs to the ABC transporter superfamily
ACETAC_09475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACETAC_09480	COG0601	transmembrane transport
ACETAC_09495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACETAC_09500	COG5002	protein histidine kinase activity
ACETAC_09520	COG1484	DNA-dependent DNA replication
ACETAC_09535	COG2059	Chromate
ACETAC_09545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACETAC_09565	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACETAC_09570	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACETAC_09580	COG0658	competence protein
ACETAC_09580	COG2333	competence protein COMEC
ACETAC_09595	COG0737	Belongs to the 5'-nucleotidase family
ACETAC_09600	COG0584	glycerophosphoryl diester phosphodiesterase
ACETAC_09605	COG3842	ATPase activity
ACETAC_09615	COG1175	transmembrane transport
ACETAC_09645	COG2188	Transcriptional regulator
ACETAC_09700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACETAC_09770	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACETAC_09775	COG3547	Transposase (IS116 IS110 IS902 family)
ACETAC_09780	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACETAC_09805	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ACETAC_09810	COG1122	ATPase activity
ACETAC_09815	COG1122	ATPase activity
ACETAC_09835	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACETAC_09845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACETAC_09850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACETAC_09870	COG0201	protein transport
ACETAC_09875	COG0200	Binds to the 23S rRNA
ACETAC_09880	COG1841	ribosomal large subunit assembly
ACETAC_09905	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACETAC_09910	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACETAC_09935	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACETAC_09940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACETAC_09945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACETAC_09960	COG0089	rRNA binding
ACETAC_09970	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACETAC_09980	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACETAC_09995	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACETAC_10000	COG1358	cellular component organization or biogenesis
ACETAC_10010	COG0085	RNA polymerase activity
ACETAC_10015	COG0222	ribosome binding
ACETAC_10035	COG0250	Participates in transcription elongation, termination and antitermination
ACETAC_10040	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACETAC_10045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACETAC_10050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACETAC_10060	COG1595	DNA-templated transcription, initiation
ACETAC_10065	COG3688	RNA-binding protein containing a PIN domain
ACETAC_10070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACETAC_10085	COG1045	serine acetyltransferase
ACETAC_10105	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACETAC_10115	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACETAC_10120	COG4956	integral membrane protein (PIN domain superfamily)
ACETAC_10130	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACETAC_10135	COG0542	response to heat
ACETAC_10140	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ACETAC_10145	COG3880	PFAM UvrB UvrC protein
ACETAC_10160	COG0281	malic enzyme
ACETAC_10165	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACETAC_10215	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACETAC_10225	COG4224	UPF0291 protein
ACETAC_10260	COG0720	synthase
ACETAC_10265	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACETAC_10270	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACETAC_10280	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACETAC_10295	COG5322	oxidoreductase activity
ACETAC_10295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACETAC_10315	COG0697	spore germination
ACETAC_10325	COG4684	Psort location CytoplasmicMembrane, score
ACETAC_10330	COG4770	biotin carboxylase activity
ACETAC_10340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACETAC_10345	COG3852	Histidine kinase
ACETAC_10360	COG0037	tRNA processing
ACETAC_10365	COG2208	phosphoserine phosphatase activity
ACETAC_10375	COG1120	ATPase activity
ACETAC_10380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACETAC_10400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACETAC_10410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACETAC_10415	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACETAC_10450	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ACETAC_10490	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ACETAC_10510	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ACETAC_10530	COG0543	2 iron, 2 sulfur cluster binding
ACETAC_10530	COG0633	Ferredoxin
ACETAC_10555	COG1192	Involved in chromosome partitioning
ACETAC_10560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACETAC_10565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACETAC_10565	COG0646	methionine synthase
ACETAC_10575	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACETAC_10580	COG3404	Formiminotransferase-cyclodeaminase
ACETAC_10585	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ACETAC_10590	COG0746	molybdenum cofactor guanylyltransferase activity
ACETAC_10595	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACETAC_10610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACETAC_10615	COG1910	domain protein
ACETAC_10625	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACETAC_10630	COG0095	Lipoate-protein ligase
ACETAC_10635	COG0509	glycine decarboxylation via glycine cleavage system
ACETAC_10640	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACETAC_10650	COG1151	hydroxylamine reductase activity
ACETAC_10660	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ACETAC_10665	COG0375	protein maturation
ACETAC_10670	COG0409	Hydrogenase expression formation protein
ACETAC_10675	COG0298	carbon dioxide binding
ACETAC_10700	COG0437	4 iron, 4 sulfur cluster binding
ACETAC_10705	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACETAC_10710	COG3260	NADH ubiquinone oxidoreductase 20
ACETAC_10715	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACETAC_10720	COG0651	ATP synthesis coupled electron transport
ACETAC_10725	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ACETAC_10735	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ACETAC_10740	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACETAC_10745	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACETAC_10750	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACETAC_10755	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACETAC_10760	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACETAC_10765	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACETAC_10770	COG0356	it plays a direct role in the translocation of protons across the membrane
ACETAC_10780	COG0303	'Molybdopterin
ACETAC_10790	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACETAC_10825	COG1122	ATPase activity
ACETAC_10830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ACETAC_10835	COG0310	cobalt ion transport
ACETAC_10840	COG0310	cobalt ion transport
ACETAC_10845	COG2033	superoxide reductase activity
ACETAC_10895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACETAC_10895	COG0730	response to heat
ACETAC_10905	COG0671	phosphoesterase, PA-phosphatase related
ACETAC_10915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACETAC_10925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACETAC_10930	COG1122	ATPase activity
ACETAC_10945	COG0310	cobalt ion transport
ACETAC_10980	COG1122	ATPase activity
ACETAC_11015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACETAC_11020	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ACETAC_11030	COG2239	Acts as a magnesium transporter
ACETAC_11035	COG0305	Participates in initiation and elongation during chromosome replication
ACETAC_11045	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ACETAC_11065	COG0629	single-stranded DNA binding
ACETAC_11075	COG4481	Protein conserved in bacteria
ACETAC_11080	COG0668	transmembrane transport
ACETAC_11085	COG0425	Belongs to the sulfur carrier protein TusA family
ACETAC_11100	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACETAC_11100	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACETAC_11115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACETAC_11120	COG1475	DNA binding
ACETAC_11125	COG1192	Involved in chromosome partitioning
ACETAC_11130	COG1475	DNA binding
ACETAC_11145	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACETAC_11150	COG1847	R3H domain protein
ACETAC_11155	COG0706	membrane insertase activity